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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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R408046-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $173.90 |
PDE4 Selective Inhibitors
Specifications & Purity | Moligand™, 10mM in DMSO |
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Biochemical and Physiological Mechanisms | The PDE4 selective inhibitor, Rolipram (ZK-62711, SB 95952), inhibited immunopurified PDE4B and PDE4D activities similarly, with IC50 values of approx. 130 nM and 240 nM respectively; an anti-inflammatory agent. |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Product Description | Information ThePDE4selective inhibitor, Rolipram (ZK-62711, SB 95952), inhibited immunopurifiedPDE4BandPDE4Dactivities similarly, with IC50 values of approx. 130 nM and 240 nM respectively; an anti-inflammatory agent. In vivo
cell lines: Concentrations: Incubation Time: Powder Purity:≥98% |
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Canonical SMILES | COC1=C(OC2CCCC2)C=C(C=C1)C3CNC(=O)C3 |
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Molecular Weight | 275.34 |
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Solubility | Solubility (25°C) In vitro DMSO: 74 mg/mL (199.79 mM); Ethanol: 3 mg/mL (8.09 mM); Water: Insoluble; |
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