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Rotigotine - ≥98%, high purity , D2-like dopamine receptor agonist, CAS No.99755-59-6, D2-like dopamine receptor agonist
Basic Description
| Synonyms | Rotigotine|99755-59-6|Neupro|Leganto|SPM 962|Rotigotine CDS Patch|(S)-6-(propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol|SPM-962|UNII-87T4T8BO2E|87T4T8BO2E|DTXSID5046772|(6S)-6-(Propyl(2-(2-thienyl)ethyl)amino)-5,6,7,8-tetrahydro-1- |
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| Specifications & Purity | Moligand™, ≥98% |
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| Storage Temp | Store at -20°C |
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| Shipped In | Ice chest + Ice pads |
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| Grade | Moligand™ |
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| Action Type | AGONIST |
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| Mechanism of action | D2-like dopamine receptor agonist |
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| Note | 卖完停产，不再备货 |
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| Product Description | Rotigotine is a dopamine receptor agonist, used in the treatment of Parkinson's disease and restless legs syndrome. |
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Names and Identifiers
| IUPAC Name | (6S)-6-[propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol |
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| INCHI | InChI=1S/C19H25NOS/c1-2-11-20(12-10-17-6-4-13-22-17)16-8-9-18-15(14-16)5-3-7-19(18)21/h3-7,13,16,21H,2,8-12,14H2,1H3/t16-/m0/s1 |
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| InChi Key | KFQYTPMOWPVWEJ-INIZCTEOSA-N |
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| Canonical SMILES | CCCN(CCC1=CC=CS1)C2CCC3=C(C2)C=CC=C3O |
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| Isomeric SMILES | CCCN(CCC1=CC=CS1)[C@H]2CCC3=C(C2)C=CC=C3O |
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| WGK Germany | 2 |
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| PubChem CID | 59227 |
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| Molecular Weight | 315.47 |
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Chemical and Physical Properties
| Solubility | DMSO 63 mg/mL; Water <1 mg/mL; Ethanol 63 mg/mL |
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| Sensitivity | Heat Sensitive |
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| Specific Rotation[α] | -42.7° (C=1,MeOH) |
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| Melt Point(°C) | 78 °C |
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Safety and Hazards(GHS)
| Pictogram(s) | GHS08, GHS07 |
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| Signal | Warning |
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| Hazard Statements | H413:May cause long lasting harmful effects to aquatic life H302:Harmful if swallowed H336:May cause drowsiness or dizziness H361:Suspected of damaging fertility or the unborn child H362:May cause harm to breast-fed children |
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| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P330:Rinse mouth. P263:Avoid contact during pregnancy/while nursing. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P319:Get medical help if you feel unwell. |
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| WGK Germany | 2 |
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