The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
RS 102895 hydrochloride - 10mM in DMSO, high purity , CAS No.1173022-16-6
Selective CCR2 receptor antagonist
Basic Description Synonyms RS 102895 hydrochloride | 1173022-16-6 | 300815-41-2 | RS-102895 Hydrochloride | RS102895 hydrochloride | RS102895 (hydrochloride) | MFCD08703093 | 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]spiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-one;hydrochloride | Spiro[4H-3,1-benzoxa Specifications & Purity 10mM in DMSO Biochemical and Physiological Mechanisms Selective CCR2 receptor antagonist (IC 50 values are 360 nM and 17.8 μM at CCR2 and CCR1 receptors, respectively). Inhibits MCP-1 and MCP-3 stimulated calcium influx (IC 50 values are 32 and 130 nM, respectively). Active in vivo . Storage Temp Store at -80°C Shipped In Ice chest + Ice pads
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]spiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-one;hydrochloride INCHI InChI=1S/C21H21F3N2O2.ClH/c22-21(23,24)16-7-5-15(6-8-16)9-12-26-13-10-20(11-14-26)17-3-1-2-4-18(17)25-19(27)28-20;/h1-8H,9-14H2,(H,25,27);1H InChi Key KRRISOFSWVKYBF-UHFFFAOYSA-N Canonical SMILES C1CN(CCC12C3=CC=CC=C3NC(=O)O2)CCC4=CC=C(C=C4)C(F)(F)F.Cl Isomeric SMILES C1CN(CCC12C3=CC=CC=C3NC(=O)O2)CCC4=CC=C(C=C4)C(F)(F)F.Cl PubChem CID 16759153 Molecular Weight 426.9
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
