Selective group I metabotropic glutamate receptor agonist which activates both mGlu1and mGlu5. Also reported to be an antagonist at metabotropic glutamate receptors linked to phospholipase D.S-enantiomeralso available.
Storage Temp
Store at -20°C,Argon charged,Desiccated
Shipped In
Ice chest + Ice pads
Grade
Moligand™
Action Type
AGONIST
Mechanism of action
Agonist of mGlu 1 receptor;Agonist of mGlu 5 receptor
Product Description
Product Describtion:
DHPG ((RS)-3,5-DHPG) is an amino acid, which acts as a selective and potent agonist of group I mGluR (mGluR 1 and mGluR 5), shows no effect on Group II or Group III mGluRs[1]. DHPG ((RS)-3,5-DHPG) is also an effective antagonist of mGluRs linked to phospholipase D.