Basic Description

Synonyms	RSV604 \| 676128-63-5 \| RSV-604 \| RSV 604 \| A-60444 \| 6NF9HI6D98 \| (S)-1-(2-fluorophenyl)-3-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)urea \| UNII-6NF9HI6D98 \| 1-(2-fluorophenyl)-3-[(3S)-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepin-3-yl]urea \| (S)-N-(2-Fluoro
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	RSV604 (A-60444), a novel benzodiazepine, is an inhibitor of respiratory syncytial virus (RSV) with EC50 of 0.86 μM. RSV604 has significant potential for the effective treatment of RSV disease. Phase 2.
Storage Temp	Protected from light,Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	Information RSV604 RSV604 (A-60444), a novel benzodiazepine, is an inhibitor of respiratory syncytial virus (RSV) with EC50 of 0.86 μM. RSV604 has significant potential for the effective treatment of RSV disease. Phase 2. Targets RSV (Cell-free assay) 0.86 μM(EC50)

Product Properties

ALogP	3.3

Associated Targets(Human)

CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)

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CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)

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CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)

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CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)

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CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

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Liver microsomes (16955 Activities)

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Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

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Human respirovirus 3 (1674 Activities)

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Rattus norvegicus (775804 Activities)

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Respiratory syncytial virus (3434 Activities)

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Human respirovirus 1 (22 Activities)

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MDCK (10148 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

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Bovine orthopneumovirus (1 Activities)

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Metapneumovirus (1 Activities)

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Pneumonia virus of mice 15 (1 Activities)

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Serum (58 Activities)

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SARS-CoV-2 (38078 Activities)

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Names and Identifiers

IUPAC Name	1-(2-fluorophenyl)-3-[(3S)-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepin-3-yl]urea
INCHI	InChI=1S/C22H17FN4O2/c23-16-11-5-7-13-18(16)25-22(29)27-20-21(28)24-17-12-6-4-10-15(17)19(26-20)14-8-2-1-3-9-14/h1-13,20H,(H,24,28)(H2,25,27,29)/t20-/m1/s1
InChi Key	MTPVBMVUENFFLL-HXUWFJFHSA-N
Canonical SMILES	C1=CC=C(C=C1)C2=NC(C(=O)NC3=CC=CC=C32)NC(=O)NC4=CC=CC=C4F
Isomeric SMILES	C1=CC=C(C=C1)C2=N[C@@H](C(=O)NC3=CC=CC=C32)NC(=O)NC4=CC=CC=C4F
PubChem CID	5279172
Molecular Weight	388.39

Certificates

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Chemical and Physical Properties

Sensitivity	Light sensitive

Safety and Hazards(GHS)

RIDADR	NONHforallmodesoftransport

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RSV604 - 10mM in DMSO, high purity , CAS No.676128-63-5

Basic Description

Product Properties

Associated Targets(Human)

Associated Targets(non-human)

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Solution Calculators

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Dilution Calculator

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