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(S)-(-)-1-Boc-2-pyrrolidinecarbonitrile - 97%, high purity , CAS No.228244-04-0

≥97%

CAS#: 228244-04-0
Formula: C₁₀H₁₆N₂O₂
Molecular Weight: 196.25
MDL number: MFCD01861224
PubChem CID: 6951263

Item Number

B119264

Grouped product items
SKU	Size	Availability	Price
B119264-500mg	500mg	In stock	$14.90
B119264-1g	1g	In stock	$21.90
B119264-5g	5g	In stock	$65.90
B119264-25g	25g	In stock	$294.90
B119264-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,061.90

View related series

Five-Membered Heterocyclic Compounds Pyrrolidines

Basic Description

Synonyms	228244-04-0\|(S)-1-Boc-2-cyanopyrrolidine\|tert-butyl (2S)-2-cyanopyrrolidine-1-carboxylate\|(S)-tert-butyl 2-cyanopyrrolidine-1-carboxylate\|(s)-1-n-boc-2-cyanopyrrolidine\|(S)-1-N-BOC-2-CYANO-PYRROLIDINE\|(S)-1-Boc-2-pyrrolidinecarbonitrile\|(S)-(-)-1-BOC-2-CY
Specifications & Purity	≥97%
Storage Temp	Protected from light,Argon charged
Shipped In	Normal
Product Description	Used in synthesis of prolyl oligopeptidase inhibitors.

Associated Targets

DPP4 Tclin Dipeptidyl peptidase 4 0 Activities

Discover Target: DPP4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PREP Tchem Prolyl endopeptidase 0 Activities

Discover Target: PREP

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	tert-butyl (2S)-2-cyanopyrrolidine-1-carboxylate
INCHI	InChI=1S/C10H16N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(12)7-11/h8H,4-6H2,1-3H3/t8-/m0/s1
InChi Key	MDMSZBHMBCNYNO-QMMMGPOBSA-N
Canonical SMILES	CC(C)(C)OC(=O)N1CCCC1C#N
Isomeric SMILES	CC(C)(C)OC(=O)N1CCC[C@H]1C#N
WGK Germany	3
PubChem CID	6951263
Molecular Weight	196.25
Reaxy-Rn	8256883

Certificates

Certificate of Analysis(COA)

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3 results found

Lot Number	Certificate Type	Date	Item
B2222232	Certificate of Analysis	Dec 27, 2021	B119264
B2222241	Certificate of Analysis	Dec 27, 2021	B119264
B2222319	Certificate of Analysis	Dec 27, 2021	B119264

Solubility

Slightly soluble in water.

Sensitivity

Moisture sensitive；Light sensitive

Specific Rotation[α]

-105.5°

Flash Point(°F)

230 °F

Flash Point(°C)

110 °C

Melt Point(°C)

33-36°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled H302+H312+H332:Harmful if swallowed, in contact with skin or if inhaled
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
Reaxy-Rn	8256883

References

1. Janice Lawandi, Sylvestre Toumieux, Valentine Seyer, Philip Campbell, Sabine Thielges, Lucienne Juillerat-Jeanneret, Nicolas Moitessier,. (2009-11-06) Constrained peptidomimetics reveal detailed geometric requirements of covalent prolyl oligopeptidase inhibitors.. Journal of medicinal chemistry, 52 ((21)): ( 6672-6684 ). [PMID:19888757]

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