(S)-3-Methyl-4-(7-((R)-3-methylmorpholino)-2-(1H-pyrazol-3-yl)thiazolo[5,4-d]pyrimidin-5-yl)morpholine , CAS No.S609431, Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta
(S)-3-Methyl-4-(7-((R)-3-methylmorpholino)-2-(1H-pyrazol-3-yl)thiazolo[5,4-d]pyrimidin-5-yl)morpholine , CAS No.S609431, Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta
Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta
1.Lim JS, Kim WI, Kang HC, Kim SH, Park AH, Park EK, Cho YW, Kim S, Kim HM, Kim JA et al.. (2015) Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy.. Nat Med, 21 (4):(395-400). [PMID:25799227][10.1021/op500134e]
2.Koh HY, Lee JH. (2018) Brain Somatic Mutations in Epileptic Disorders.. Mol Cells, 41 (10):(881-888). [PMID:30352490][10.1021/op500134e]
3.Iffland 2nd PH, Crino PB. (2019) The role of somatic mutational events in the pathogenesis of epilepsy.. Curr Opin Neurol, 32 (2):(191-197). [PMID:30762606][10.1021/op500134e]
4.Bonazzi S, Goold CP, Gray A, Thomsen NM, Nunez J, Karki RG, Gorde A, Biag JD, Malik HA, Sun Y et al.. (2020) Discovery of a Brain-Penetrant ATP-Competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS Disorders.. J Med Chem, 63 (3):(1068-1083). [PMID:31955578][10.1021/op500134e]
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