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(S)-4-Carboxyphenylglycine - ≥99%(HPLC), high purity , CAS No.134052-73-6, Antagonist of mGlu 1 receptor;Antagonist of mGlu 5 receptor
Competitive group I mGlu antagonist; also weak group II agonist
Basic Description
Specifications & Purity | Moligand™, ≥99%(HPLC) |
Biochemical and Physiological Mechanisms | Competitive group I metabotropic glutamate receptor antagonist, with selectivity for mGlu1a/1aover mGlu5a/5b.RacemateandR-enantiomeralso available. |
Storage Temp | Room temperature |
Shipped In | Normal |
Grade | Moligand™ |
Action Type | ANTAGONIST |
Mechanism of action | Antagonist of mGlu 1 receptor;Antagonist of mGlu 5 receptor |
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Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
IUPAC Name | 4-[(S)-amino(carboxy)methyl]benzoic acid |
INCHI | InChI=1S/C9H9NO4/c10-7(9(13)14)5-1-3-6(4-2-5)8(11)12/h1-4,7H,10H2,(H,11,12)(H,13,14)/t7-/m0/s1 |
InChi Key | VTMJKPGFERYGJF-ZETCQYMHSA-N |
Canonical SMILES | C1=CC(=CC=C1C(C(=O)O)N)C(=O)O |
Isomeric SMILES | C1=CC(=CC=C1[C@@H](C(=O)O)N)C(=O)O |
PubChem CID | 5311459 |
Molecular Weight | 195.17 |
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Chemical and Physical Properties
Solubility | Solvent:1eq. NaOH, Max Conc. mg/mL: 19.52, Max Conc. mM: 100 with gentle warming |
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