The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
(S)-(-)-5-Iodowillardiine - ≥98%(HPLC), high purity , CAS No.140187-25-3, Agonist of GluK1
Highly potent and subtype-selective kainate agonist
Basic Description Synonyms IODO-WILLARDIINE|140187-25-3|(S)-(-)-5-IODOWILLARDIINE|S-5-Iodowillardiine|(s)-5-iodowillardiine|5-(S)-Iodowillardiine|CHEMBL121915|(2S)-2-amino-3-(5-iodo-2,4-dioxopyrimidin-1-yl)propanoic acid|2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PR Specifications & Purity Moligand™, ≥98%(HPLC) Biochemical and Physiological Mechanisms Demonstrates high affinity for the kainate receptor subtype hGluK1 (formerly hGluR5) (Ki = 0.24 nM) and 600-4000-fold selectivity over both the AMPA receptor subtypes and the homomeric kainate receptor hGluK2 (formerly hGluR6).
Storage Temp Room temperature Shipped In Normal Grade Moligand™ Action Type AGONIST Mechanism of action Agonist of GluK1
Names and Identifiers Pubchem Sid 488189851 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488189851 IUPAC Name (2S)-2-amino-3-(5-iodo-2,4-dioxopyrimidin-1-yl)propanoic acid INCHI InChI=1S/C7H8IN3O4/c8-3-1-11(2-4(9)6(13)14)7(15)10-5(3)12/h1,4H,2,9H2,(H,13,14)(H,10,12,15)/t4-/m0/s1 InChi Key AXXYLTBQIQBTES-BYPYZUCNSA-N Canonical SMILES C1=C(C(=O)NC(=O)N1CC(C(=O)O)N)I Isomeric SMILES C1=C(C(=O)NC(=O)N1C[C@@H](C(=O)O)N)I Alternate CAS 140187-25-3 PubChem CID 447196 MeSH Entry Terms 5-iodowillardiine Molecular Weight 325.06
Chemical and Physical Properties Solubility Solvent:1.1eq. NaOH, Max Conc. mg/mL: 8.12, Max Conc. mM: 25
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
D2326174