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(S)-α-methylhistamine , CAS No.S611166, Agonist of H 3 receptor;Agonist of H 4 receptor

Item Number
S611166
Grouped product items
SKUSizeAvailabilityPrice Qty
S611166-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$700.90
S611166-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90

Basic Description

SynonymsAKOS006339244 | NCGC00024659-02 | CHEBI:125525 | (2S)-1-(1H-Imidazol-4-yl)-2-propanamine | BDBM22905 | (S)-alpha-MeHA | Tocris-0572 | (S)-2-(1H-Imidazol-4-yl)-1-methyl-ethylamine | alpha-methylhistamine-dihydrobromide-(S)-(+) | SCHEMBL4008535 | BDBM504725
Specifications & PurityMoligand™
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of H 3 receptor;Agonist of H 4 receptor

Associated Targets(Human)

HRH4 Tchem Histamine H4 receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HRH3 Tclin Histamine H3 receptor (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NFKB1 Tclin Nuclear factor NF-kappa-B p105 subunit (1459 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THPO Tbio Thrombopoietin (834 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hrh4 Histamine H4 receptor (388 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences
Histamine H2 receptor antagonistANTAGONISTALA1941Histamine H2 receptorSINGLE PROTEINHomo sapiens

DailyMed: [1]


Histamine H2 receptor antagonistANTAGONISTALA1941Histamine H2 receptorSINGLE PROTEINHomo sapiens

ISBN: [1]


Histamine H2 receptor agonistAGONISTALA1941Histamine H2 receptorSINGLE PROTEINHomo sapiens

ISBN: [1]


PubMed: [1]


Histamine H2 receptor antagonistANTAGONISTALA1941Histamine H2 receptorSINGLE PROTEINHomo sapiens

DailyMed: [1]


Histamine H2 receptor antagonistANTAGONISTALA1941Histamine H2 receptorSINGLE PROTEINHomo sapiens

FDA: [1]


Histamine H2 receptor antagonistANTAGONISTALA1941Histamine H2 receptorSINGLE PROTEINHomo sapiens

ISBN: [1]


Histamine H2 receptor antagonistANTAGONISTALA1941Histamine H2 receptorSINGLE PROTEINHomo sapiens

FDA: [1]


Histamine H2 receptor antagonistANTAGONISTALA1941Histamine H2 receptorSINGLE PROTEINHomo sapiens

PubMed: [1]


Histamine H2 receptor agonistAGONISTALA1941Histamine H2 receptorSINGLE PROTEINHomo sapiens

DailyMed: [1]


ISBN: [1]


PubMed: [1] , [2]


Histamine H2 receptor antagonistANTAGONISTALA1941Histamine H2 receptorSINGLE PROTEINHomo sapiens

PubMed: [1] , [2] , [3] , [4]


Names and Identifiers

IUPAC Name (2S)-1-(3H-imidazol-4-yl)propan-2-amine
INCHI InChI=1S/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9)/t5-/m0/s1
InChi Key XNQIOISZPFVUFG-YFKPBYRVSA-N
Canonical SMILES C[C@@H](Cc1cnc[nH]1)N
Isomeric SMILES C[C@@H](CC1=CN=CN1)N
PubChem CID 6603865

Certificates

C of A & Other Certificates

Related Documents

Solution Calculators