Basic Description

Synonyms	S-allyl-L-cysteine \| 21593-77-1 \| S-Allylcysteine \| (R)-3-(Allylthio)-2-aminopropanoic acid \| L-DEOXYALLIIN \| S-Allyl cysteine \| L-Cysteine, S-2-propenyl- \| allyl-cysteine \| DEOXYALLIIN \| S-prop-2-en-1-yl-L-cysteine \| S-2-propenyl-L-cysteine \| CHEBI:74077 \| S-allyl-laevo-cystein
Specifications & Purity	10mM in Water
Biochemical and Physiological Mechanisms	Antioxidant agent. Inhibits reperfusion-induced HIF-1α, VEGF, and MMP-9 upregulation. Shows selective neuroprotective effects against amyloid β-protein-induced cell death. Shows anti-ischemic effects in vivo. Orally active.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	L-Deoxyalliin is a water-soluble organosulfur obtained from garlic. L-Deoxyalliin is a proven candidate for chemoprevention in a clinical trial. A water-soluble organosulfur

Associated Targets(Human)

TLR2 Tchem Toll-like receptor 2 (975 Activities)

Discover Target: TLR2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(2R)-2-amino-3-prop-2-enylsulfanylpropanoic acid
INCHI	InChI=1S/C6H11NO2S/c1-2-3-10-4-5(7)6(8)9/h2,5H,1,3-4,7H2,(H,8,9)/t5-/m0/s1
InChi Key	ZFAHNWWNDFHPOH-YFKPBYRVSA-N
Canonical SMILES	C=CCSCC(C(=O)O)N
Isomeric SMILES	C=CCSC[C@@H](C(=O)O)N
WGK Germany	3
RTECS	HA2466200
PubChem CID	9793905
Molecular Weight	161.22
Reaxy-Rn	1722895

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Sensitivity	Air sensitive
Specific Rotation[α]	-15° (C=1,H2O)

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H317:May cause an allergic skin reaction
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse.
WGK Germany	3
RTECS	HA2466200
Reaxy-Rn	1722895

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Miaomiao Liu, Siqi Jing, Tiantian Xie, Haiyan Liu, Ligai Bai. (2024) Fabrication of a bio-based polymer adsorbent and its application for extraction and determination of glycosides from Huangqi Liuyi decoction. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 240 (115947). [PMID:38181557] [10.1016/j.jpba.2023.115947]
2. Jing Nie, Rui Weng, Chunlin Li, Xiuhua Liu, Fang Wang, Karyne M. Rogers, Yongzhong Qian, Yongzhi Zhang, Yuwei Yuan. (2022) Chemometric origin classification of Chinese garlic using sulfur-containing compounds, assisted by stable isotopes and bioelements. FOOD CHEMISTRY, 394 (133557). [PMID:35759834] [10.1016/j.foodchem.2022.133557]
3. Rong Xu, Siyan Qiu, Jie Zhang, Xiaoli Liu, Ling Zhang, Haizhu Xing, Min You, Man Wang, Yuting Lu, Peng Zhang, Jing Zhu. (2022) Silibinin Schiff Base Derivatives Counteract CCl4-Induced Acute Liver Injury by Enhancing Anti-Inflammatory and Antiapoptotic Bioactivities. Drug Design Development and Therapy, 16 (1441-1456). [PMID:35601675] [10.2147/DDDT.S356847]
4. Qiang Chen, Chunjing Guo, Xiudi Zhou, Yanguo Su, Huimin Guo, Min Cao, Jing Li, Yue Zhang, Weiyi Zhao, Xin Gao, Shuqi Mi, Daquan Chen. (2022) N-acetylneuraminic acid and chondroitin sulfate modified nanomicelles with ROS-sensitive H2S donor via targeting E-selectin receptor and CD44 receptor for the efficient therapy of atherosclerosis. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 211 (259). [PMID:35513096] [10.1016/j.ijbiomac.2022.04.180]
5. Xiaoying Zhang, Cuifeng Wang, Jiamin Wu, Yajun Liu, Zeping Yang, Ye Zhang, Xiaofeng Sui, Min Li, Min Feng. (2017) An acid-seeking carrier-free drug achieves high antitumor activity via a “solution-particle” transition. JOURNAL OF CONTROLLED RELEASE, 262 (305). [PMID:28797579] [10.1016/j.jconrel.2017.08.008]

References

1. Miaomiao Liu, Siqi Jing, Tiantian Xie, Haiyan Liu, Ligai Bai. (2024) Fabrication of a bio-based polymer adsorbent and its application for extraction and determination of glycosides from Huangqi Liuyi decoction. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 240 (115947). [PMID:38181557] [10.1016/j.jpba.2023.115947]
2. Jing Nie, Rui Weng, Chunlin Li, Xiuhua Liu, Fang Wang, Karyne M. Rogers, Yongzhong Qian, Yongzhi Zhang, Yuwei Yuan. (2022) Chemometric origin classification of Chinese garlic using sulfur-containing compounds, assisted by stable isotopes and bioelements. FOOD CHEMISTRY, 394 (133557). [PMID:35759834] [10.1016/j.foodchem.2022.133557]
3. Rong Xu, Siyan Qiu, Jie Zhang, Xiaoli Liu, Ling Zhang, Haizhu Xing, Min You, Man Wang, Yuting Lu, Peng Zhang, Jing Zhu. (2022) Silibinin Schiff Base Derivatives Counteract CCl4-Induced Acute Liver Injury by Enhancing Anti-Inflammatory and Antiapoptotic Bioactivities. Drug Design Development and Therapy, 16 (1441-1456). [PMID:35601675] [10.2147/DDDT.S356847]
4. Qiang Chen, Chunjing Guo, Xiudi Zhou, Yanguo Su, Huimin Guo, Min Cao, Jing Li, Yue Zhang, Weiyi Zhao, Xin Gao, Shuqi Mi, Daquan Chen. (2022) N-acetylneuraminic acid and chondroitin sulfate modified nanomicelles with ROS-sensitive H2S donor via targeting E-selectin receptor and CD44 receptor for the efficient therapy of atherosclerosis. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 211 (259). [PMID:35513096] [10.1016/j.ijbiomac.2022.04.180]
5. Xiaoying Zhang, Cuifeng Wang, Jiamin Wu, Yajun Liu, Zeping Yang, Ye Zhang, Xiaofeng Sui, Min Li, Min Feng. (2017) An acid-seeking carrier-free drug achieves high antitumor activity via a “solution-particle” transition. JOURNAL OF CONTROLLED RELEASE, 262 (305). [PMID:28797579] [10.1016/j.jconrel.2017.08.008]

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S-Allyl-L-cysteine - 10mM in Water, high purity , CAS No.21593-77-1