(S)-(+)-Camptothecin - 97%, high purity , CAS No.7689-03-4

Item Number

C111282

• Synonyms: camptothecin | 7689-03-4 | Camptothecine | (S)-(+)-Camptothecin | Campathecin | (+)-Camptothecine | d-Camptothecin | (+)-Camptothecin | 20(S)-Camptothecine | 21,22-Secocamptothecin-21-oic acid lactone | NSC94600 | Camptothecine (S,+) | CHEMBL65 | (S)-4-ethyl-4-hydroxy-1H-Pyrano[3'
• Specifications & Purity: ≥97%
• Biochemical and Physiological Mechanisms: (S)-(+)-Camptothecin binds irreversibly to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. The enzyme complex is ubiquinated and destroyed by the 2
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

(S)-(+)-Camptothecin binds irreversibly to the DNA-topoisomerase I complex，Blocks the cell cycle in S-phase