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S-(+)-CBPG , CAS No.180465-02-5, Antagonist of mGlu 1 receptor;Agonist of mGlu 5 receptor
a structurally new group I mGluR antagonist
Basic Description Synonyms S-(+)-2-(3'-Carboxybicyclo[1.1.1]pentyl)glycine; UPF 596 Specifications & Purity Moligand™ Storage Temp Store at 2-8°C Shipped In Wet ice Grade Moligand™ Action Type AGONIST, ANTAGONIST Mechanism of action Antagonist of mGlu 1 receptor;Agonist of mGlu 5 receptor Product Description S-(+)-CBPG is a potent and selective, structurally new group I metabotropic glutamate receptor (mGluR) antagonist.
Names and Identifiers IUPAC Name 3-[(S)-amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-carboxylic acid INCHI InChI=1S/C8H11NO4/c9-4(5(10)11)7-1-8(2-7,3-7)6(12)13/h4H,1-3,9H2,(H,10,11)(H,12,13)/t4-,7?,8?/m1/s1 InChi Key KNSHLWJBSDBBRH-XOJFDHPMSA-N Canonical SMILES C1C2(CC1(C2)C(=O)O)C(C(=O)O)N Isomeric SMILES C1C2(CC1(C2)C(=O)O)[C@@H](C(=O)O)N PubChem CID 5311040 MeSH Entry Terms 2-(3'-carboxybicyclo(1.1.1)pentyl)glycine;CBPG compound;UPF 596;UPF-596;UPF596 Molecular Weight 185.18
Chemical and Physical Properties Solubility Soluble in water or DMSO.
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