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S-(+)-CBPG , CAS No.180465-02-5, Antagonist of mGlu 1 receptor;Agonist of mGlu 5 receptor

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S-(+)-CBPG , CAS No.180465-02-5, Antagonist of mGlu 1 receptor;Agonist of mGlu 5 receptor

Moligand™

CAS#: 180465-02-5
Formula: C₈H₁₁NO₄
Molecular Weight: 185.18
PubChem CID: 5311040

Item Number

S386556

Grouped product items
SKU	Size	Availability	Price	Qty
S386556-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$33.90
S386556-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$126.90

a structurally new group I mGluR antagonist

View related series

mGlu1 receptor Antagonist mGlu5 receptor Agonist

Basic Description

Specifications & Purity	Moligand™
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Moligand™
Action Type	AGONIST, ANTAGONIST
Mechanism of action	Antagonist of mGlu 1 receptor;Agonist of mGlu 5 receptor
Product Description	S-(+)-CBPG is a potent and selective, structurally new group I metabotropic glutamate receptor (mGluR) antagonist. S-(+)-CBPGis a structurally new group I mGluR antagonist

Associated Targets(Human)

GRM1 Tchem Metabotropic glutamate receptor 1 (1 Activities)

Discover Target: GRM1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRM5 Tchem Metabotropic glutamate receptor 5 (1 Activities)

Discover Target: GRM5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRM4 Tchem Metabotropic glutamate receptor 4 (2320 Activities)

Discover Target: GRM4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GRM1 Tchem Metabotropic glutamate receptor 1 (2309 Activities)

Discover Target: GRM1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Grm2 Metabotropic glutamate receptor 2 (1326 Activities)

Discover Target: Grm2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	3-[(S)-amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-carboxylic acid
INCHI	InChI=1S/C8H11NO4/c9-4(5(10)11)7-1-8(2-7,3-7)6(12)13/h4H,1-3,9H2,(H,10,11)(H,12,13)/t4-,7?,8?/m1/s1
InChi Key	KNSHLWJBSDBBRH-XOJFDHPMSA-N
Canonical SMILES	C1C2(CC1(C2)C(=O)O)C(C(=O)O)N
Isomeric SMILES	C1C2(CC1(C2)C(=O)O)[C@@H](C(=O)O)N
PubChem CID	5311040
MeSH Entry Terms	2-(3'-carboxybicyclo(1.1.1)pentyl)glycine;CBPG compound;UPF 596;UPF-596;UPF596
Molecular Weight	185.18

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Solubility	Soluble in water or DMSO.

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