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(S)-(-)-HA-966 - ≥98%(HPLC), high purity , CAS No.111821-58-0
NMDA antagonist/partial agonist
Basic Description
| Synonyms | D05746 | 3C1G86U80C | HY-100822A | AKOS024457304 | J-002639 | SR-01000597726 | (3S)-3-amino-1-hydroxypyrrolidin-2-one | Cerebyx (TN) | (-)-HA-966 | HA-966, (S)- | HMS3266E17 | Q27257016 | SCHEMBL667643 | Tocris-0282 | (S)-(-)-3-Amino-1-hydroxypyrrolidin-2 |
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| Specifications & Purity | ≥98%(HPLC) |
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| Biochemical and Physiological Mechanisms | Possesses potent sedative and ataxic action, probably through disruption of striatal dopaminergic mechanisms.R-enantiomeralso available. |
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| Storage Temp | Room temperature |
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| Shipped In | Normal |
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Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | (3S)-3-amino-1-hydroxypyrrolidin-2-one |
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| INCHI | InChI=1S/C4H8N2O2/c5-3-1-2-6(8)4(3)7/h3,8H,1-2,5H2/t3-/m0/s1 |
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| InChi Key | HCKUBNLZMKAEIN-VKHMYHEASA-N |
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| Canonical SMILES | C1CN(C(=O)C1N)O |
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| Isomeric SMILES | C1CN(C(=O)[C@H]1N)O |
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| PubChem CID | 183351 |
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| Molecular Weight | 116.12 |
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Chemical and Physical Properties
| Solubility | Solvent:water, Max Conc. mg/mL: None, Max Conc. mM: 100 |
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Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
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| Signal | Warning |
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| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
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| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
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