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(S)-(-)-HA-966 - ≥98%(HPLC), high purity , CAS No.111821-58-0

  • ≥98%(HPLC)
Item Number
S287240
Grouped product items
SKUSizeAvailabilityPrice Qty
S287240-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
S287240-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$255.90

NMDA antagonist/partial agonist

Basic Description

Synonyms111821-58-0|(S)-(-)-HA-966|(S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one|(3S)-3-amino-1-hydroxypyrrolidin-2-one|(S)-(-)-HA 966|HA-966, (S)-|(-)-HA 966|2-Pyrrolidinone, 3-amino-1-hydroxy-, (S)-|(S)-ha-966|3C1G86U80C|UNII-3C1G86U80C|(S)-HA 966|Tocris-0282|(-)-H
Specifications & Purity≥98%(HPLC)
Biochemical and Physiological MechanismsPossesses potent sedative and ataxic action, probably through disruption of striatal dopaminergic mechanisms.R-enantiomeralso available.
Storage TempRoom temperature
Shipped InNormal

Associated Targets

CYP1A2 Tchem Cytochrome P450 1A2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2D6 Tclin Cytochrome P450 2D6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2C19 Tchem Cytochrome P450 2C19 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2C9 Tchem Cytochrome P450 2C9 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (3S)-3-amino-1-hydroxypyrrolidin-2-one
INCHI InChI=1S/C4H8N2O2/c5-3-1-2-6(8)4(3)7/h3,8H,1-2,5H2/t3-/m0/s1
InChi Key HCKUBNLZMKAEIN-VKHMYHEASA-N
Canonical SMILES C1CN(C(=O)C1N)O
Isomeric SMILES C1CN(C(=O)[C@H]1N)O
PubChem CID 183351
Molecular Weight 116.12

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySolvent:water, Max Conc. mg/mL: None, Max Conc. mM: 100

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

Related Documents

Solution Calculators