(S)-Naproxen Acyl-β-D-glucuronide , CAS No.41945-43-1

Item Number
N337212
Grouped product items
SKUSizeAvailabilityPrice Qty
N337212-1mg
1mg
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$1,220.90
N337212-5mg
5mg
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$5,491.90
N337212-10mg
10mg
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$9,413.90
N337212-2g
2g
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$14,999.90

a metabolite of Naproxen

Basic Description

Synonyms41945-43-1 | Naproxen Glucuronide | (S)-Naproxen-beta-D-glucuronide | CHEMBL3526991 | (S)-Naproxen Acyl-beta-D-glucuronide | (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(2S)-2-(6-methoxynaphthalen-2-yl)propanoyl]oxyoxane-2-carboxylic acid | (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy
Storage TempStore at -20°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

CES1 Tchem Liver carboxylesterase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CES2 Tchem Cocaine esterase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
UGT1A3 Tbio UDP-glucuronosyltransferase 1-3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CES2 Tchem Carboxylesterase 2 (583 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CES1 Tchem Acyl coenzyme A:cholesterol acyltransferase (1029 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A3 Tbio UDP-glucuronosyltransferase 1-3 (217 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(2S)-2-(6-methoxynaphthalen-2-yl)propanoyl]oxyoxane-2-carboxylic acid
INCHI InChI=1S/C20H22O9/c1-9(10-3-4-12-8-13(27-2)6-5-11(12)7-10)19(26)29-20-16(23)14(21)15(22)17(28-20)18(24)25/h3-9,14-17,20-23H,1-2H3,(H,24,25)/t9-,14-,15-,16+,17-,20-/m0/s1
InChi Key XRHIELLXTVJOKM-ODXKUVGNSA-N
Canonical SMILES CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)OC3C(C(C(C(O3)C(=O)O)O)O)O
Isomeric SMILES C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C(=O)O)O)O)O
PubChem CID 181715
Molecular Weight 406.38

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Melt Point(°C)80-82°C (lit.)

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

Precautionary Statements

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

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Solution Calculators