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S- (+)-Rolipram - ≥99%, high purity , CAS No.85416-73-5

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S- (+)-Rolipram - ≥99%, high purity , CAS No.85416-73-5

≥99%

CAS#: 85416-73-5
Formula: C₁₆H₂₁NO₃
Molecular Weight: 275.34
MDL number: MFCD03093861
PubChem CID: 158758

Item Number

S129683

Grouped product items
SKU	Size	Availability	Price
S129683-5mg	5mg	In stock	$70.90
S129683-10mg	10mg	In stock	$117.90
S129683-25mg	25mg	In stock	$265.90
S129683-50mg	50mg	In stock	$459.90
S129683-100mg	100mg	In stock	$810.90

Discover S- (+)-Rolipram by Aladdin Scientific in ≥99% for only $70.90. Available - in Ligands at Aladdin Scientific. PDE4 inhibitor; less active enantiomer Tags: Pharmaceutical ingredients.

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Pharmaceutical ingredients

Basic Description

Synonyms	(S)-(+)-rolipram\|85416-73-5\|S-(+)-Rolipram\|(S)-ROLIPRAM\|S- (+)-Rolipram\|(+)-rolipram\|(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE\|(S)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one\|Rolipram, (+)-\|(4S)-4-(3-cyclopentyloxy-4-methoxyph
Specifications & Purity	≥99%
Storage Temp	Store at -20°C
Shipped In	Dry ice

Associated Targets

PDE4D Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4D 1 Activities

Discover Target: PDE4D

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(4S)-4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one
INCHI	InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18)/t12-/m1/s1
InChi Key	HJORMJIFDVBMOB-GFCCVEGCSA-N
Canonical SMILES	COC1=C(C=C(C=C1)C2CC(=O)NC2)OC3CCCC3
Isomeric SMILES	COC1=C(C=C(C=C1)[C@@H]2CC(=O)NC2)OC3CCCC3
PubChem CID	158758
Molecular Weight	275.34
Reaxy-Rn	6687797

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5 results found

Lot Number	Certificate Type	Date	Item
I2227591	Certificate of Analysis	Jul 10, 2024	S129683
I2227593	Certificate of Analysis	Jul 10, 2024	S129683
I2227597	Certificate of Analysis	Jul 10, 2024	S129683
I2227628	Certificate of Analysis	Jul 10, 2024	S129683
I2227627	Certificate of Analysis	Jul 09, 2024	S129683

Chemical and Physical Properties

Solubility	DMSO 55 mg/mL Water <1 mg/mL Ethanol 55 mg/mL
Sensitivity	Heat Sensitive
Specific Rotation[α]	32° (C=0.5,MeOH)
Melt Point(°C)	134 °C

Safety and Hazards(GHS)

Reaxy-Rn	6687797

References

1. Blazon M et al.. (2021) N-type calcium channels control GABAergic transmission in brain areas related to fear and anxiety.. OBM Neurobiol, 5 [PMID:33521586]

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