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(S,S)-(+)-Tetrandrine - analytical standard,≥98%(HPLC),for drug analysis, high purity , CAS No.518-34-3

11 Citations

analytical standard

Moligand™

≥98%(HPLC)
for food analysis

CAS#: 518-34-3
Formula: C₃₈H₄₂N₂O₆
Molecular Weight: 622.75
Beilstein Registry Number: 877811
MDL number: MFCD08689909
PubChem CID: 73078

Item Number

T107322

Grouped product items
SKU	Size	Availability	Price
T107322-20mg	20mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$9.90
T107322-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$27.90
T107322-200mg	200mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$43.90
T107322-500mg	500mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$104.90
T107322-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$166.90

Calcium channel blocker. Anti-inflammatory and antitumor agent.

View related series

Pyridines Six-Membered Heterocyclic Compounds

Basic Description

Synonyms	CCG-38342 \| CHEBI:49 \| NSC91771 \| NSC-91771 \| TETRANDRINE [WHO-DD] \| BBL029400 \| CA-260 \| HMS1791J21 \| HMS3402J21 \| KBio2_000795 \| NSC 77037 \| S,S-(+)-Tetrandrine \| DL-Tetrandine \| d-Tetrandr \| (1S,14S)-9,20,21,25-tetramethoxy-15,30-dimethyl-7,23-dioxa-15
Specifications & Purity	Moligand™, analytical standard, ≥98%(HPLC), for food analysis
Biochemical and Physiological Mechanisms	Calcium channel blocker. (IC 50 values are 8 and 20 µM for L -type and T-type calcium channels respectively). Various pharmacological effects. Shows anti-inflammatory and antitumor activity. Inhibits osteoclast differentiation in vivo.
Shipped In	Normal
Grade	analytical standard, Moligand™
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets(Human)

GMNN Tbio Geminin (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RORC Tchem Nuclear receptor ROR-gamma (0 Activities)

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ABCB1 Tchem Multidrug resistance protein 1 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KMT2A Tchem Histone-lysine N-methyltransferase 2A (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 (0 Activities)

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FEN1 Tchem Flap endonuclease 1 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TXNRD1 Tclin Thioredoxin reductase 1, cytoplasmic (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SMN1 Tchem Survival motor neuron protein (0 Activities)

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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SMAD3 Tchem Mothers against decapentaplegic homolog 3 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

POLI Tchem DNA polymerase iota (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALOX15B Tchem Arachidonate 15-lipoxygenase B (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CACNA1C Tclin Voltage-dependent L-type calcium channel subunit alpha-1C (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ATXN2 Tbio Ataxin-2 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM5 Tclin Muscarinic acetylcholine receptor M5 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

APOBEC3G Tchem DNA dC->dU-editing enzyme APOBEC-3G (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ACHE Tclin Acetylcholinesterase (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA1B Tclin Alpha-1B adrenergic receptor (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLA Tclin Alpha-galactosidase A (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ATAD5 Tbio ATPase family AAA domain-containing protein 5 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

BCHE Tclin Cholinesterase (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLP1R Tclin Glucagon-like peptide 1 receptor (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TP53 Tchem Cellular tumor antigen p53 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KDM4A Tchem Lysine-specific demethylase 4A (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NPC1 Tchem NPC intracellular cholesterol transporter 1 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ACHE Tclin Acetylcholinesterase (18204 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLA Tclin Alpha-galactosidase A (5444 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TP53 Tchem Cellular tumor antigen p53 (48468 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A498 (42825 Activities)

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A673 (619 Activities)

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ACHN (49357 Activities)

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CAKI-1 (44928 Activities)

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CCRF-CEM (65223 Activities)

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COLO 205 (50209 Activities)

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DLD-1 (17511 Activities)

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DMS-273 (14108 Activities)

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DU-145 (51482 Activities)

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HL-60 (67320 Activities)

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HT-29 (80576 Activities)

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K562 (73714 Activities)

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KM12 (47707 Activities)

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M14 (47487 Activities)

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MCF7 (126967 Activities)

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MDA-MB-453 (1139 Activities)

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MOLT-4 (49676 Activities)

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Panel NCI-60 (60 carcinoma cell lines) (1088 Activities)

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OVCAR-3 (48710 Activities)

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OVCAR-4 (44535 Activities)

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OVCAR-5 (45555 Activities)

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OVCAR-8 (47708 Activities)

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PC-3 (62116 Activities)

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RPMI-8226 (44974 Activities)

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RXF 393 (41971 Activities)

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SF-295 (48000 Activities)

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SK-MEL-2 (46422 Activities)

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SK-MEL-28 (48833 Activities)

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SK-MEL-5 (47095 Activities)

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SK-OV-3 (52876 Activities)

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SN12C (47755 Activities)

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SNB-19 (46794 Activities)

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SNB-78 (14240 Activities)

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TK-10 (45540 Activities)

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U-251 (51189 Activities)

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U-937 (7138 Activities)

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UACC-257 (46019 Activities)

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UACC-62 (47335 Activities)

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UO-31 (46270 Activities)

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XF498 (12972 Activities)

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786-0 (47912 Activities)

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A549 (127892 Activities)

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NCI/ADR-RES (33767 Activities)

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T47D (39041 Activities)

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ECa-109 cell line (1254 Activities)

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Associated Targets(non-human)

Abcb1b P-glycoprotein 1 (174 Activities)

Discover Target: Abcb1b

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hdac6 Histone deacetylase 6 (222 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Staphylococcus aureus (210822 Activities)

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Mycobacterium tuberculosis (203094 Activities)

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Entamoeba histolytica (2676 Activities)

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Plasmodium falciparum (966862 Activities)

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Candida albicans (78123 Activities)

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P388 (20296 Activities)

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P388/ADR (1216 Activities)

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Vero (26788 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BCHE Cholinesterase (8742 Activities)

Discover Target: BCHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Aorta (2975 Activities)

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Rorc Nuclear receptor ROR-gamma (89407 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Chrm1 Muscarinic acetylcholine receptor (3770 Activities)

Discover Target: Chrm1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Adra1b Adrenergic receptor alpha-1 (5652 Activities)

Discover Target: Adra1b

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cacna1c Voltage-gated L-type calcium channel (1164 Activities)

Discover Target: Cacna1c

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

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Vero C1008 (1716 Activities)

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Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(1S,14S)-9,20,21,25-tetramethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaene
INCHI	InChI=1S/C38H42N2O6/c1-39-15-13-25-20-32(42-4)34-22-28(25)29(39)17-23-7-10-27(11-8-23)45-33-19-24(9-12-31(33)41-3)18-30-36-26(14-16-40(30)2)21-35(43-5)37(44-6)38(36)46-34/h7-12,19-22,29-30H,13-18H2,1-6H3/t29-,30-/m0/s1
InChi Key	WVTKBKWTSCPRNU-KYJUHHDHSA-N
Canonical SMILES	CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC
Isomeric SMILES	CN1CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)C[C@H]6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC
WGK Germany	3
RTECS	XE9350000
PubChem CID	73078
Molecular Weight	622.75
Beilstein	877811
Reaxy-Rn	79006

Database links

PubChem CID	73078
CAS Registry No.	518-34-3

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot Number	Certificate Type	Date	Item
K2110174	Certificate of Analysis	Aug 02, 2023	T107322
K2110175	Certificate of Analysis	Aug 02, 2023	T107322
K2110212	Certificate of Analysis	Aug 02, 2023	T107322
B2303942	Certificate of Analysis	Feb 10, 2023	T107322
D1816152	Certificate of Analysis	Jan 26, 2022	T107322

Chemical and Physical Properties

Melt Point(°C)	219-222°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS07
Signal	Danger
Hazard Statements	H302:Harmful if swallowed H300:Fatal if swallowed
Precautionary Statements	P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P301+P317:IF SWALLOWED: Get medical help.
WGK Germany	3
RTECS	XE9350000
Reaxy-Rn	79006

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Wenqian Shang, Jing Zhang, Haibo Song, Shunfei Zhu, Aimin Zhang, Yushuang Hua, Shujun Han, Yan Fu. (2021) Mechanism of Tetrandrine Against Endometrial Cancer Based on Network Pharmacology. Drug Design Development and Therapy, 15 ( 2907–2919). [PMID:34262258] [10.2147/DDDT.S307670]
2. Zhou Yufeng, Duan Liguang, Huang Yixin, Liu Yaqi, Wang Lijuan, Qiao Xiaoqiang. (2021) Ionic Liquid 1-Vinyl-3-dodecylimidazole Bromide Embedded Hybrid Monolithic Column and Its Versatile Post-modification with Amino Acids. Journal of Analysis and Testing, 5 (4): (387-395). [PMID:] [10.1007/s41664-021-00171-2]
3. Liu Mingyang, Du Xuejun, Xu Ke, Yan Binwei, Fan Zaibi, Gao Zideng, Ren Xueqin. (2021) A cationic quantum dot-based ratiometric fluorescent probe to visually detect berberine hydrochloride in human blood serums. Journal of Analytical Science and Technology, 12 (1): (1-9). [PMID:] [10.1186/s40543-021-00261-x]
4. Qing Wang, Ling Tong, Lin Yao, Peng Zhang, Li Xu. (2016) Fingerprinting of traditional Chinese medicines on the C18-Diol mixed-mode column in online or offline two-dimensional liquid chromatography on the single column modes. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 125 (205). [PMID:27031576] [10.1016/j.jpba.2016.03.033]
5. Qing Wang, Yao Long, Lin Yao, Li Xu, Zhi-Guo Shi, Lanying Xu. (2016) Preparation, characterization and application of a reversed phase liquid chromatography/hydrophilic interaction chromatography mixed-mode C18-DTT stationary phase. TALANTA, 146 (442). [PMID:26695288] [10.1016/j.talanta.2015.09.009]
6. Qing Wang, Zhi-Yuan Luo, Mao Ye, Yu-Zhuo Wang, Li Xu, Zhi-guo Shi, Lanying Xu. (2015) Preparation, chromatographic evaluation and application of adenosine 5′-monophosphate modified ZrO2/SiO2 stationary phase in hydrophilic interaction chromatography. JOURNAL OF CHROMATOGRAPHY A, 1383 (58). [PMID:25627970] [10.1016/j.chroma.2015.01.017]
7. Zhisheng Xie, Xinjun Xu, Chunyan Xie, Zhikun Liang, Mei Yang, Jieyun Huang, Depo Yang. (2014) PREPARATIVE ISOLATION OF TETRANDRINE AND FANGCHINOLINE FROM RADIX STEPHANIA TETRANDRA USING REVERSED-PHASE FLASH CHROMATOGRAPHY. JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, [PMID:] [10.1080/10826076.2012.745139]
8. Ruan Lin, Huang Huan-Sen, Jin Wen-Xiang, Chen Hai-Ming, Li Xiong-Juan, Gong Qing-Juan. (2013) Tetrandrine Attenuated Cerebral Ischemia/Reperfusion Injury and Induced Differential Proteomic Changes in a MCAO Mice Model Using 2-D DIGE. NEUROCHEMICAL RESEARCH, 38 (9): (1871-1879). [PMID:23780673] [10.1007/s11064-013-1093-1]
9. Lihong Liu, Shenglan Li, Zilin Chen. (2012) Simultaneous determination of tetrandrine and fangchinoline in herbal medicine Stephania tetrandra S. Moore by liquid chromatography with electrochemical detection. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 61 (252). [PMID:22196802] [10.1016/j.jpba.2011.11.027]
10. Qing Wang,Jie Chen,Kun Huang,Xin Zhang,Li Xu,Zhi-guo Shi. (2014-12-07) Preparation, characterization and application of N-methylene phosphonic acid chitosan grafted magnesia-zirconia stationary phase.. Analytica chimica acta, 854 (191-201). [PMID:25479884]
11. Liyun Ma,Si-Min Liu,Lin Yao,Li Xu. (2014-12-22) Preparation and chromatographic performance evaluation of cucurbit[7]uril immobilized silica.. Journal of chromatography. A, 1376 (64-73). [PMID:25528071]

References

1. King VF, Garcia ML, Himmel D, Reuben JP, Lam YK, Pan JX, Han GQ, Kaczorowski GJ. (1988) Interaction of tetrandrine with slowly inactivating calcium channels. Characterization of calcium channel modulation by an alkaloid of Chinese medicinal herb origin.. J Biol Chem, 263 (5): (2238-44). [PMID:2448307] [10.1021/op500134e]
2. Sakurai Y, Kolokoltsov AA, Chen CC, Tidwell MW, Bauta WE, Klugbauer N, Grimm C, Wahl-Schott C, Biel M, Davey RA. (2015) Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment.. Science, 347 (6225): (995-8). [PMID:25722412] [10.1021/op500134e]
3. Heister PM, Poston RN. (2020) Pharmacological hypothesis: TPC2 antagonist tetrandrine as a potential therapeutic agent for COVID-19.. Pharmacol Res Perspect, 8 (5): (e00653). [PMID:32930523] [10.1021/op500134e]
4. Sun J, Song P, Wang Y, Chen Y. (2019) Clinical efficacy of acetylcysteine combined with tetrandrine tablets in the treatment of silicosis and the effect on serum IL-6 and TNF-α.. Exp Ther Med, 18 (5): (3383-3388). [PMID:31602212] [10.1021/op500134e]
5. Freeman SA et al.. (2020) Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance.. Science, 367 (6475): (301-305). [PMID:31806695]
6. Hoffmann M et al.. (2016) The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent.. PLoS One, 11 (2): (e0149651). [PMID:26901159]
7. Wenqian Shang, Jing Zhang, Haibo Song, Shunfei Zhu, Aimin Zhang, Yushuang Hua, Shujun Han, Yan Fu. (2021) Mechanism of Tetrandrine Against Endometrial Cancer Based on Network Pharmacology. Drug Design Development and Therapy, 15 ( 2907–2919). [PMID:34262258] [10.2147/DDDT.S307670]
8. Zhou Yufeng, Duan Liguang, Huang Yixin, Liu Yaqi, Wang Lijuan, Qiao Xiaoqiang. (2021) Ionic Liquid 1-Vinyl-3-dodecylimidazole Bromide Embedded Hybrid Monolithic Column and Its Versatile Post-modification with Amino Acids. Journal of Analysis and Testing, 5 (4): (387-395). [PMID:] [10.1007/s41664-021-00171-2]
9. Liu Mingyang, Du Xuejun, Xu Ke, Yan Binwei, Fan Zaibi, Gao Zideng, Ren Xueqin. (2021) A cationic quantum dot-based ratiometric fluorescent probe to visually detect berberine hydrochloride in human blood serums. Journal of Analytical Science and Technology, 12 (1): (1-9). [PMID:] [10.1186/s40543-021-00261-x]
10. Qing Wang, Ling Tong, Lin Yao, Peng Zhang, Li Xu. (2016) Fingerprinting of traditional Chinese medicines on the C18-Diol mixed-mode column in online or offline two-dimensional liquid chromatography on the single column modes. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 125 (205). [PMID:27031576] [10.1016/j.jpba.2016.03.033]
11. Qing Wang, Yao Long, Lin Yao, Li Xu, Zhi-Guo Shi, Lanying Xu. (2016) Preparation, characterization and application of a reversed phase liquid chromatography/hydrophilic interaction chromatography mixed-mode C18-DTT stationary phase. TALANTA, 146 (442). [PMID:26695288] [10.1016/j.talanta.2015.09.009]
12. Qing Wang, Zhi-Yuan Luo, Mao Ye, Yu-Zhuo Wang, Li Xu, Zhi-guo Shi, Lanying Xu. (2015) Preparation, chromatographic evaluation and application of adenosine 5′-monophosphate modified ZrO2/SiO2 stationary phase in hydrophilic interaction chromatography. JOURNAL OF CHROMATOGRAPHY A, 1383 (58). [PMID:25627970] [10.1016/j.chroma.2015.01.017]
13. Zhisheng Xie, Xinjun Xu, Chunyan Xie, Zhikun Liang, Mei Yang, Jieyun Huang, Depo Yang. (2014) PREPARATIVE ISOLATION OF TETRANDRINE AND FANGCHINOLINE FROM RADIX STEPHANIA TETRANDRA USING REVERSED-PHASE FLASH CHROMATOGRAPHY. JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, [PMID:] [10.1080/10826076.2012.745139]
14. Ruan Lin, Huang Huan-Sen, Jin Wen-Xiang, Chen Hai-Ming, Li Xiong-Juan, Gong Qing-Juan. (2013) Tetrandrine Attenuated Cerebral Ischemia/Reperfusion Injury and Induced Differential Proteomic Changes in a MCAO Mice Model Using 2-D DIGE. NEUROCHEMICAL RESEARCH, 38 (9): (1871-1879). [PMID:23780673] [10.1007/s11064-013-1093-1]
15. Lihong Liu, Shenglan Li, Zilin Chen. (2012) Simultaneous determination of tetrandrine and fangchinoline in herbal medicine Stephania tetrandra S. Moore by liquid chromatography with electrochemical detection. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 61 (252). [PMID:22196802] [10.1016/j.jpba.2011.11.027]
16. Qing Wang,Jie Chen,Kun Huang,Xin Zhang,Li Xu,Zhi-guo Shi. (2014-12-07) Preparation, characterization and application of N-methylene phosphonic acid chitosan grafted magnesia-zirconia stationary phase.. Analytica chimica acta, 854 (191-201). [PMID:25479884]
17. Liyun Ma,Si-Min Liu,Lin Yao,Li Xu. (2014-12-22) Preparation and chromatographic performance evaluation of cucurbit[7]uril immobilized silica.. Journal of chromatography. A, 1376 (64-73). [PMID:25528071]

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(S,S)-(+)-Tetrandrine - analytical standard,≥98%(HPLC),for drug analysis, high purity , CAS No.518-34-3

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