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(S)-UH 301 , CAS No.S613749, Antagonist of 5-HT 1A receptor
Basic Description
| Synonyms | 5-Fhdpat | 127126-21-0 | UH 301 | UH-301 | 5-Fluoro-8-hydroxy-2-(dipropylamino)tetralin | CHEMBL22778 | 1G916IMD7L | (S)-UH-301 | 1-Naphthalenol, 7-(dipropylamino)-4-fluoro-5,6,7,8-tetrahydro-, (S)- | 1-NAPHTHALENOL, 7-(DIPROPYLAMINO)-4-FLUORO-5,6,7,8-TETRAHYDRO-, (7S)- | (s |
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| Specifications & Purity | Moligand™ |
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| Grade | Moligand™ |
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| Action Type | ANTAGONIST |
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| Mechanism of action | Antagonist of 5-HT 1A receptor |
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Associated Targets(Human)
Associated Targets(non-human)
Names and Identifiers
| IUPAC Name | 7-(dipropylamino)-4-fluoro-5,6,7,8-tetrahydronaphthalen-1-ol |
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| INCHI | InChI=1S/C16H24FNO/c1-3-9-18(10-4-2)12-5-6-13-14(11-12)16(19)8-7-15(13)17/h7-8,12,19H,3-6,9-11H2,1-2H3/t12-/m0/s1 |
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| InChi Key | FNKBVTBXFLSTPB-LBPRGKRZSA-N |
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| Canonical SMILES | CCCN([C@H]1CCc2c(C1)c(O)ccc2F)CCC |
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| Isomeric SMILES | CCCN(CCC)[C@H]1CCC2=C(C=CC(=C2C1)O)F |
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| PubChem CID | 122187 |
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References
| 1. Newman-Tancredi A, Gavaudan S, Conte C, Chaput C, Touzard M, Verrièle L, Audinot V, Millan MJ. (1998) Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.. Eur J Pharmacol, 355 (2-3): (245-56). [PMID:9760039] |
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