Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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S298558-25g | 25g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $29.90 | |
S298558-100g | 100g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $34.90 | |
S298558-500g | 500g | In stock | $120.90 |
Synonyms | AI3-38107 | 1,1-Dioxide-1,2-benzisothiazolin-3-one | HSDB 669 | 1,2-Dihydro-2-ketobenzisosulphonazole | Benzosulfinide | 3-Hydroxybenzisothiazole-S,S-dioxide | Anhydro-o-sulfaminebenzoic acid | o-Benzoic sulfimide | Benzo-sulphinide | Kristallose | SACCHA |
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Specifications & Purity | Moligand™, ≥97% |
Storage Temp | Argon charged |
Shipped In | Normal |
Grade | Moligand™ |
Product Description | Usually used in high performance liquid chromatographic method for the simultaneous separation and determination of acesulfame potassium, saccharine and aspartame;and also used in sweet preference test of rats. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 1,1-dioxo-1,2-benzothiazol-3-one |
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INCHI | InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9) |
InChi Key | CVHZOJJKTDOEJC-UHFFFAOYSA-N |
Canonical SMILES | C1=CC=C2C(=C1)C(=O)NS2(=O)=O |
Isomeric SMILES | C1=CC=C2C(=C1)C(=O)NS2(=O)=O |
WGK Germany | 2 |
RTECS | DE4200000 |
Alternate CAS | 128-44-9,6381-61-9,81-07-2 |
PubChem CID | 5143 |
NSC Number | 5349 |
MeSH Entry Terms | Calcium, Saccharin;Saccharin;Saccharin Calcium;Saccharin Sodium |
Molecular Weight | 183.18 |
Beilstein | 6888 |
Reaxy-Rn | 6888 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
D2422111 | Certificate of Analysis | Apr 28, 2024 | S298558 |
D2415435 | Certificate of Analysis | Apr 15, 2024 | S298558 |
L2206082 | Certificate of Analysis | Dec 10, 2022 | S298558 |
G1804042 | Certificate of Analysis | May 09, 2022 | S298558 |
K2310239 | Certificate of Analysis | May 09, 2022 | S298558 |
Sensitivity | Moisture sensitive |
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Melt Point(°C) | 229°C |
WGK Germany | 2 |
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RTECS | DE4200000 |
Reaxy-Rn | 6888 |
Merck Index | 8311 |
1. Qian Gao, Jiansong Li, Ruina Ma, Yongzhe Fan, An Du, Mingxu Yang, Xue Zhao, Yi Bian. (2023) Facile electrodeposition of corrosion-resistant superhydrophobic Ni-plated stainless-steel mesh for oil–water separation. Materials Today Communications, 37 (8): (107032). [PMID:18495667] [10.1016/j.mtcomm.2023.107032] |
2. Chen Zhirong, Yao Yang, Yuan Shenfeng, Yin Hong. (2023) Measurement of Critical Temperatures, Critical Pressures and Densities of Acetone–Water Solutions for Simulation. JOURNAL OF SOLUTION CHEMISTRY, 52 (12): (1331-1351). [PMID:] [10.1007/s10953-023-01320-0] |
3. Jiabei Zhang, Yucheng Wu, Zhaoyang Zhang, Shicheng Sun, Shaojing Gu, Shuai Yang, Hao Zhu. (2023) Picosecond laser remelting of electrodeposited NiP coating: Parameters optimization and electrochemical corrosion behavior. SURFACE & COATINGS TECHNOLOGY, 471 (129877). [PMID:] [10.1016/j.surfcoat.2023.129877] |
4. Xiao Jia, Yingying Wang, Junlei Tang, Kaikai Song, Hailong Zhang, Bing Lin, Hongpeng Zheng. (2023) FeNi-LDH@Ni film modified stainless-steel as self-supported electrodes for efficient and stable overall water splitting in alkaline environments. SURFACE & COATINGS TECHNOLOGY, 464 (129502). [PMID:] [10.1016/j.surfcoat.2023.129502] |
5. Yuehua Deng, Wei Luo, Zhiyong Zheng, Guixuan Wei, Shiyuan Liu, Yanbin Jiang, Huaiyu Yang. (2023) Prediction of co-amorphous formation using non-bonded interaction energy: Molecular dynamic simulation and experimental validation. CHEMICAL ENGINEERING SCIENCE, 272 (118618). [PMID:] [10.1016/j.ces.2023.118618] |
6. Yang Xintong, Chen Yang, Qiao Ning. (2023) Effects of polyvinylpyrrolidone and poly (ethylene glycol) on preparation of ibuprofen pharmaceutical cocrystal. Brazilian Journal of Pharmaceutical Sciences, 58 (e18768). [PMID:] [10.1590/s2175-97902022e18768] |
7. Liu Cansen, Zhen Haowen, Huang Qishan, Chen Wanlin, Mai Yongjin, Zhang Liuyan, Jie Xiaohua. (2023) Improvement in Tribological and Anticorrosion Performances of Co-MoS2 Composite Coatings. JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE, 32 (5): (2237-2248). [PMID:] [10.1007/s11665-022-07260-y] |
8. Xiuhu Li, Rongrong Deng, Qibo Zhang. (2022) Cobalt-phosphorous coatings with tunable composition fabricated by additive-controlled electrodeposition from choline chloride-ethylene glycol deep eutectic solvent for anti-corrosion application. SURFACE & COATINGS TECHNOLOGY, 443 (128610). [PMID:] [10.1016/j.surfcoat.2022.128610] |
9. Shuhan Dong, Yang Yang, Ruina Ma, An Du, Mingxu Yang, Yongzhe Fan, Xue Zhao, Xiaoming Cao. (2022) Investigation of the anti-corrosion performance of a Cu/Ni–B4C superhydrophobic coating with self-cleaning and abrasion resistance properties. SURFACE & COATINGS TECHNOLOGY, 441 (128568). [PMID:] [10.1016/j.surfcoat.2022.128568] |
10. Qifei Chen, Huaming Hou, Dan Zheng, Xueming Xu, Xingjun Xi, Yisheng Chen. (2022) HPTLC screening of saccharin in beverages by densitometry quantification and SERS confirmation. RSC Advances, 12 (14): (8317-8322). [PMID:35424832] [10.1039/D1RA09416E] |
11. Yuehua Deng, Wenhao Deng, Wenquan Huang, Zhiyong Zheng, Rui Zhang, Shiyuan Liu, Yanbin Jiang. (2022) Norfloxacin co-amorphous salt systems: Effects of molecular descriptors on the formation and physical stability of co-amorphous systems. CHEMICAL ENGINEERING SCIENCE, 253 (117549). [PMID:] [10.1016/j.ces.2022.117549] |
12. Jiahui Chen, Minshan Guo, Runhui Fan, Yayun Peng, Ting Cai. (2022) Impact of bile salt on solution-mediated phase transformation of pharmaceutical cocrystals: The importance of coformer release kinetics. CHEMICAL ENGINEERING JOURNAL, 435 (134928). [PMID:] [10.1016/j.cej.2022.134928] |
13. Hui Jin, Renjie Ji, Tiancong Dong, Shuo Liu, Fan Zhang, Lilong Zhao, Chi Ma, Baoping Cai, Yonghong Liu. (2022) Efficient fabrication and characterization of Ni-Fe-WC composite coatings with high corrosion resistance. Journal of Materials Research and Technology-JMR&T, 16 (152). [PMID:] [10.1016/j.jmrt.2021.11.145] |
14. Shuhan Dong, Yang Yang, Tingting Liang, Ruina Ma, An Du, Mingxu Yang, Yongzhe Fan, Xue Zhao, Xiaoming Cao. (2021) Construction and corrosion resistance of Ni-B4C superhydrophobic composite coatings on Q235 steel. SURFACE & COATINGS TECHNOLOGY, 422 (127551). [PMID:] [10.1016/j.surfcoat.2021.127551] |
15. Long Yingtao, Liang Jianjun, Xue Yinghao. (2021) Ultrasound-assisted electrodeposition synthesis of nZVI-Pd/AC toward reductive degradation of methylene blue. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 28 (47): (67098-67107). [PMID:34244938] [10.1007/s11356-021-15316-0] |
16. Ferry Saputra, Yu-Heng Lai, Rey Arturo T. Fernandez, Allan Patrick G. Macabeo, Hong-Thih Lai, Jong-Chin Huang, Chung-Der Hsiao. (2021) Acute and Sub-Chronic Exposure to Artificial Sweeteners at the Highest Environmentally Relevant Concentration Induce Less Cardiovascular Physiology Alterations in Zebrafish Larvae. Biology-Basel, 10 (6): (548). [PMID:34207293] [10.3390/biology10060548] |
17. Xinyuan Wang, Lei Wang, Changlin Yao, Guanying Xie, Shuhong Song, Huimin Li, Yaqian Qu, Xutang Tao. (2021) Novel Formulations of the Antiviral Drug Favipiravir: Improving Permeability and Tabletability. CRYSTAL GROWTH & DESIGN, 21 (7): (3807–3817). [PMID:] [10.1021/acs.cgd.1c00150] |
18. Yang Chen, Yao Zhengjun, Zhang Fan, Oleksandr Moliar. (2021) Repairing the specified track on the copper coating surface via area-selective electrodeposition. JOURNAL OF MATERIALS RESEARCH, 36 (4): (812-821). [PMID:] [10.1557/s43578-020-00036-x] |
19. Haijian Liu, Miao Wang, Zhenxiang Li, Chengjie Xin, Guofu Huang. (2020) A fluorescence sensing method for brilliant blue with gold nanoclusters based on the inner filter effect. Analytical Methods, 12 (37): (4551-4555). [PMID:32870183] [10.1039/D0AY01355B] |
20. Yao Tong, Hongsheng Li, Shangru Zhai, Kai Wang, Qingda An. (2020) Thermodynamic analysis and molecular dynamic simulation of the solubility of saccharin in three binary solvent mixtures. JOURNAL OF CHEMICAL THERMODYNAMICS, 141 (105952). [PMID:] [10.1016/j.jct.2019.105952] |
21. Baosong Li, Shengsong Du, Tianyong Mei. (2019) Pulse electrodepsoited Ni-Cu/TiN-ZrO2 nanocomposite coating: microstructural and electrochemical properties. Materials Research Express, 6 (9): (96433). [PMID:] [10.1088/2053-1591/ab31e9] |
22. Yao Tong, Shangru Zhai, Kai Wang, Hongsheng Li, Qingda An. (2019) Determination and correlation of solubility and solution thermodynamics of saccharin in different pure solvents. JOURNAL OF CHEMICAL THERMODYNAMICS, 133 (70). [PMID:] [10.1016/j.jct.2019.02.005] |
23. Xiong Pan, Saige Wang, Nan Shi, Hua Fang, Yunlong Yu. (2018) Biodegradation and detoxification of chlorimuron-ethyl by Enterobacter ludwigii sp. CE-1. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 150 (34). [PMID:29268112] [10.1016/j.ecoenv.2017.12.023] |
24. Hao Zhang, Ying Zhu, Ning Qiao, Yang Chen, Linghuan Gao. (2017) Preparation and Characterization of Carbamazepine Cocrystal in Polymer Solution. Pharmaceutics, 9 (4): (54). [PMID:29194387] [10.3390/pharmaceutics9040054] |
25. Yongqi Hua, Tingting Jiang, Kun Wang, Mingmei Wu, Shuqin Song, Yi Wang, Panagiotis Tsiakaras. (2016) Efficient Pt-free electrocatalyst for oxygen reduction reaction: Highly ordered mesoporous N and S co-doped carbon with saccharin as single-source molecular precursor. APPLIED CATALYSIS B-ENVIRONMENTAL, 194 (202). [PMID:] [10.1016/j.apcatb.2016.04.056] |
1. Qian Gao, Jiansong Li, Ruina Ma, Yongzhe Fan, An Du, Mingxu Yang, Xue Zhao, Yi Bian. (2023) Facile electrodeposition of corrosion-resistant superhydrophobic Ni-plated stainless-steel mesh for oil–water separation. Materials Today Communications, 37 (8): (107032). [PMID:18495667] [10.1016/j.mtcomm.2023.107032] |
2. Chen Zhirong, Yao Yang, Yuan Shenfeng, Yin Hong. (2023) Measurement of Critical Temperatures, Critical Pressures and Densities of Acetone–Water Solutions for Simulation. JOURNAL OF SOLUTION CHEMISTRY, 52 (12): (1331-1351). [PMID:] [10.1007/s10953-023-01320-0] |
3. Jiabei Zhang, Yucheng Wu, Zhaoyang Zhang, Shicheng Sun, Shaojing Gu, Shuai Yang, Hao Zhu. (2023) Picosecond laser remelting of electrodeposited NiP coating: Parameters optimization and electrochemical corrosion behavior. SURFACE & COATINGS TECHNOLOGY, 471 (129877). [PMID:] [10.1016/j.surfcoat.2023.129877] |
4. Xiao Jia, Yingying Wang, Junlei Tang, Kaikai Song, Hailong Zhang, Bing Lin, Hongpeng Zheng. (2023) FeNi-LDH@Ni film modified stainless-steel as self-supported electrodes for efficient and stable overall water splitting in alkaline environments. SURFACE & COATINGS TECHNOLOGY, 464 (129502). [PMID:] [10.1016/j.surfcoat.2023.129502] |
5. Yuehua Deng, Wei Luo, Zhiyong Zheng, Guixuan Wei, Shiyuan Liu, Yanbin Jiang, Huaiyu Yang. (2023) Prediction of co-amorphous formation using non-bonded interaction energy: Molecular dynamic simulation and experimental validation. CHEMICAL ENGINEERING SCIENCE, 272 (118618). [PMID:] [10.1016/j.ces.2023.118618] |
6. Yang Xintong, Chen Yang, Qiao Ning. (2023) Effects of polyvinylpyrrolidone and poly (ethylene glycol) on preparation of ibuprofen pharmaceutical cocrystal. Brazilian Journal of Pharmaceutical Sciences, 58 (e18768). [PMID:] [10.1590/s2175-97902022e18768] |
7. Liu Cansen, Zhen Haowen, Huang Qishan, Chen Wanlin, Mai Yongjin, Zhang Liuyan, Jie Xiaohua. (2023) Improvement in Tribological and Anticorrosion Performances of Co-MoS2 Composite Coatings. JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE, 32 (5): (2237-2248). [PMID:] [10.1007/s11665-022-07260-y] |
8. Xiuhu Li, Rongrong Deng, Qibo Zhang. (2022) Cobalt-phosphorous coatings with tunable composition fabricated by additive-controlled electrodeposition from choline chloride-ethylene glycol deep eutectic solvent for anti-corrosion application. SURFACE & COATINGS TECHNOLOGY, 443 (128610). [PMID:] [10.1016/j.surfcoat.2022.128610] |
9. Shuhan Dong, Yang Yang, Ruina Ma, An Du, Mingxu Yang, Yongzhe Fan, Xue Zhao, Xiaoming Cao. (2022) Investigation of the anti-corrosion performance of a Cu/Ni–B4C superhydrophobic coating with self-cleaning and abrasion resistance properties. SURFACE & COATINGS TECHNOLOGY, 441 (128568). [PMID:] [10.1016/j.surfcoat.2022.128568] |
10. Qifei Chen, Huaming Hou, Dan Zheng, Xueming Xu, Xingjun Xi, Yisheng Chen. (2022) HPTLC screening of saccharin in beverages by densitometry quantification and SERS confirmation. RSC Advances, 12 (14): (8317-8322). [PMID:35424832] [10.1039/D1RA09416E] |
11. Yuehua Deng, Wenhao Deng, Wenquan Huang, Zhiyong Zheng, Rui Zhang, Shiyuan Liu, Yanbin Jiang. (2022) Norfloxacin co-amorphous salt systems: Effects of molecular descriptors on the formation and physical stability of co-amorphous systems. CHEMICAL ENGINEERING SCIENCE, 253 (117549). [PMID:] [10.1016/j.ces.2022.117549] |
12. Jiahui Chen, Minshan Guo, Runhui Fan, Yayun Peng, Ting Cai. (2022) Impact of bile salt on solution-mediated phase transformation of pharmaceutical cocrystals: The importance of coformer release kinetics. CHEMICAL ENGINEERING JOURNAL, 435 (134928). [PMID:] [10.1016/j.cej.2022.134928] |
13. Hui Jin, Renjie Ji, Tiancong Dong, Shuo Liu, Fan Zhang, Lilong Zhao, Chi Ma, Baoping Cai, Yonghong Liu. (2022) Efficient fabrication and characterization of Ni-Fe-WC composite coatings with high corrosion resistance. Journal of Materials Research and Technology-JMR&T, 16 (152). [PMID:] [10.1016/j.jmrt.2021.11.145] |
14. Shuhan Dong, Yang Yang, Tingting Liang, Ruina Ma, An Du, Mingxu Yang, Yongzhe Fan, Xue Zhao, Xiaoming Cao. (2021) Construction and corrosion resistance of Ni-B4C superhydrophobic composite coatings on Q235 steel. SURFACE & COATINGS TECHNOLOGY, 422 (127551). [PMID:] [10.1016/j.surfcoat.2021.127551] |
15. Long Yingtao, Liang Jianjun, Xue Yinghao. (2021) Ultrasound-assisted electrodeposition synthesis of nZVI-Pd/AC toward reductive degradation of methylene blue. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 28 (47): (67098-67107). [PMID:34244938] [10.1007/s11356-021-15316-0] |
16. Ferry Saputra, Yu-Heng Lai, Rey Arturo T. Fernandez, Allan Patrick G. Macabeo, Hong-Thih Lai, Jong-Chin Huang, Chung-Der Hsiao. (2021) Acute and Sub-Chronic Exposure to Artificial Sweeteners at the Highest Environmentally Relevant Concentration Induce Less Cardiovascular Physiology Alterations in Zebrafish Larvae. Biology-Basel, 10 (6): (548). [PMID:34207293] [10.3390/biology10060548] |
17. Xinyuan Wang, Lei Wang, Changlin Yao, Guanying Xie, Shuhong Song, Huimin Li, Yaqian Qu, Xutang Tao. (2021) Novel Formulations of the Antiviral Drug Favipiravir: Improving Permeability and Tabletability. CRYSTAL GROWTH & DESIGN, 21 (7): (3807–3817). [PMID:] [10.1021/acs.cgd.1c00150] |
18. Yang Chen, Yao Zhengjun, Zhang Fan, Oleksandr Moliar. (2021) Repairing the specified track on the copper coating surface via area-selective electrodeposition. JOURNAL OF MATERIALS RESEARCH, 36 (4): (812-821). [PMID:] [10.1557/s43578-020-00036-x] |
19. Haijian Liu, Miao Wang, Zhenxiang Li, Chengjie Xin, Guofu Huang. (2020) A fluorescence sensing method for brilliant blue with gold nanoclusters based on the inner filter effect. Analytical Methods, 12 (37): (4551-4555). [PMID:32870183] [10.1039/D0AY01355B] |
20. Yao Tong, Hongsheng Li, Shangru Zhai, Kai Wang, Qingda An. (2020) Thermodynamic analysis and molecular dynamic simulation of the solubility of saccharin in three binary solvent mixtures. JOURNAL OF CHEMICAL THERMODYNAMICS, 141 (105952). [PMID:] [10.1016/j.jct.2019.105952] |
21. Baosong Li, Shengsong Du, Tianyong Mei. (2019) Pulse electrodepsoited Ni-Cu/TiN-ZrO2 nanocomposite coating: microstructural and electrochemical properties. Materials Research Express, 6 (9): (96433). [PMID:] [10.1088/2053-1591/ab31e9] |
22. Yao Tong, Shangru Zhai, Kai Wang, Hongsheng Li, Qingda An. (2019) Determination and correlation of solubility and solution thermodynamics of saccharin in different pure solvents. JOURNAL OF CHEMICAL THERMODYNAMICS, 133 (70). [PMID:] [10.1016/j.jct.2019.02.005] |
23. Xiong Pan, Saige Wang, Nan Shi, Hua Fang, Yunlong Yu. (2018) Biodegradation and detoxification of chlorimuron-ethyl by Enterobacter ludwigii sp. CE-1. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 150 (34). [PMID:29268112] [10.1016/j.ecoenv.2017.12.023] |
24. Hao Zhang, Ying Zhu, Ning Qiao, Yang Chen, Linghuan Gao. (2017) Preparation and Characterization of Carbamazepine Cocrystal in Polymer Solution. Pharmaceutics, 9 (4): (54). [PMID:29194387] [10.3390/pharmaceutics9040054] |
25. Yongqi Hua, Tingting Jiang, Kun Wang, Mingmei Wu, Shuqin Song, Yi Wang, Panagiotis Tsiakaras. (2016) Efficient Pt-free electrocatalyst for oxygen reduction reaction: Highly ordered mesoporous N and S co-doped carbon with saccharin as single-source molecular precursor. APPLIED CATALYSIS B-ENVIRONMENTAL, 194 (202). [PMID:] [10.1016/j.apcatb.2016.04.056] |