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Safinamide Mesylate - ≥98% (HPLC), high purity , Monoamine oxidase B inhibitor, CAS No.202825-46-5, Monoamine oxidase B inhibitor
Basic Description Synonyms AS-75602 | NW-1015 | PNU 151774E | 202825-46-5 (mesylate) | J-013174 | Safinamide (mesylate) | Safinamide mesilate | D10191 | HMS3884O17 | PNU-151774E,FCE28073 | Fce 28073 | Fce-26743 | Safinamide mesilate (JAN) | Equfina (TN) | SW219452-1 | Safinamide me Specifications & Purity ≥98%(HPLC) Biochemical and Physiological Mechanisms Safinamide is a dopamine reuptake inhibitor by being a highly selective inhibitor of MAO-B (IC50 = 98 nM. Additionally, this compound has a high affinity for Na+ channels (IC50 = 8 μM. Storage Temp Store at 2-8°C Shipped In Wet ice Action Type INHIBITOR Mechanism of action Monoamine oxidase B inhibitor Note 卖完停产，不再备货 Product Description Safinamide Mesylate is mesylate salt of Safinamide, selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A.
Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers Pubchem Sid 488194228 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488194228 IUPAC Name (2S)-2-[[4-[(3-fluorophenyl)methoxy]phenyl]methylamino]propanamide;methanesulfonic acid INCHI InChI=1S/C17H19FN2O2.CH4O3S/c1-12(17(19)21)20-10-13-5-7-16(8-6-13)22-11-14-3-2-4-15(18)9-14;1-5(2,3)4/h2-9,12,20H,10-11H2,1H3,(H2,19,21);1H3,(H,2,3,4)/t12-;/m0./s1 InChi Key YKOCHIUQOBQIAC-YDALLXLXSA-N Canonical SMILES CC(C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F.CS(=O)(=O)O Isomeric SMILES C[C@@H](C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F.CS(=O)(=O)O WGK Germany 3 PubChem CID 3038502 Molecular Weight 398.45
Chemical and Physical Properties Solubility DMSO 80 mg/mL Water 80 mg/mL Ethanol 13 mg/mL
Safety and Hazards(GHS) Pictogram(s) GHS06 , GHS09 , GHS05 Signal Danger Hazard Statements H301: Toxic if swallowed
H318: Causes serious eye damage
H400: Very toxic to aquatic life
Precautionary Statements P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310: IF SWALLOWED: Immediately call a POISON CENTER/doctor/...
WGK Germany 3
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E1529109