SAFit1 - 10mM in DMSO, high purity , CAS No.1643125-32-9(DMSO)

  • 10mM in DMSO
Item Number
S655396
Grouped product items
SKUSizeAvailabilityPrice Qty
S655396-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$740.90

Basic Description

Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsSAFit1 is a FK506 binding protein 51 ( FKBP51 )-specific inhibitor with a K i of 4±0.3 nM.
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

SAFit1 is a FK506 binding protein 51 ( FKBP51 )-specific inhibitor with a K i of 4±0.3 nM

In Vitro

SAFit1 (1-1000 nM) potently stimulates neurite outgrowth in two neuronal cell lines (N2a and SH-SY5Y) as well as in primary hippocampal neurons. SAFit1 is active over a wide concentration range. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:Ki: 4±0.3 nM (FKBP51), >50000 nM (FKBP52)

Associated Targets(Human)

FKBP1A Tclin Peptidyl-prolyl cis-trans isomerase FKBP1A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FKBP5 Tchem Peptidyl-prolyl cis-trans isomerase FKBP5 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Canonical SMILES COC1=C(C=C(C=C1)CCC(C2=CC(=CC=C2)OCC(=O)O)OC(=O)C3CCCCN3C(=O)C(C4CCCCC4)C5=CC(=C(C(=C5)OC)OC)OC)OC
Molecular Weight 747.87

Certificates

Certificate of Analysis(COA)

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Related Documents

Solution Calculators