Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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S126053-5mg | 5mg | In stock | $90.90 | |
S126053-25mg | 25mg | In stock | $409.90 | |
S126053-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,474.90 |
Synonyms | salinomycin | Procoxacin | 53003-10-4 | Coxistac | Bio-cox | Salinomicina | Salinomycine | Salinomycinum | UNII-62UXS86T64 | HSDB 7032 | 62UXS86T64 | K 364 | AHR 3096 | EINECS 258-290-1 | Salinomycine [INN-French] | Salinomycinum [INN-Latin] | Salinomicina [INN-Spanish] | DTXSID4048486 | CH |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Salinomycin is a polyether potassium ionophore antibiotic, which promotes cation movement across biological membranes via exchange-diffusion. As a result of this cation exchange, the transmembrane gradients are altered, which leads to changes in cellular |
Storage Temp | Protected from light,Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Product Description | Salinomycin is an antibacterial and coccidiostat ionophore therapeutic drug. |
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IUPAC Name | (2R)-2-[(2R,5S,6R)-6-[(2S,3S,4S,6R)-6-[(3S,5S,7R,9S,10S,12R,15R)-3-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoic acid |
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INCHI | InChI=1S/C42H70O11/c1-11-29(38(46)47)31-15-14-23(4)36(50-31)27(8)34(44)26(7)35(45)30(12-2)37-24(5)22-25(6)41(51-37)19-16-32(43)42(53-41)21-20-39(10,52-42)33-17-18-40(48,13-3)28(9)49-33/h16,19,23-34,36-37,43-44,48H,11-15,17-18,20-22H2,1-10H3,(H,46,47)/t23-,24-,25+,26-,27-,28-,29+,30-,31+,32+,33+,34+,36+,37-,39-,40+,41-,42-/m0/s1 |
InChi Key | KQXDHUJYNAXLNZ-XQSDOZFQSA-N |
Canonical SMILES | CCC(C1CCC(C(O1)C(C)C(C(C)C(=O)C(CC)C2C(CC(C3(O2)C=CC(C4(O3)CCC(O4)(C)C5CCC(C(O5)C)(CC)O)O)C)C)O)C)C(=O)O |
Isomeric SMILES | CC[C@H]([C@H]1CC[C@@H]([C@@H](O1)[C@@H](C)[C@@H]([C@H](C)C(=O)[C@H](CC)[C@@H]2[C@H](C[C@H]([C@]3(O2)C=C[C@H]([C@@]4(O3)CC[C@@](O4)(C)[C@H]5CC[C@@]([C@@H](O5)C)(CC)O)O)C)C)O)C)C(=O)O |
WGK Germany | 3 |
RTECS | VO8620000 |
PubChem CID | 3085092 |
Molecular Weight | 751 |
PubChem CID | 3085092 |
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CAS Registry No. | 53003-10-4 |
ChEMBL Ligand | CHEMBL1208572 |
DrugBank Ligand | DB11544 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
B2224069 | Certificate of Analysis | Dec 20, 2023 | S126053 |
B2224073 | Certificate of Analysis | Dec 20, 2023 | S126053 |
B2224076 | Certificate of Analysis | Dec 20, 2023 | S126053 |
Sensitivity | Light sensitive |
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Pictogram(s) | GHS06 |
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Signal | Danger |
Hazard Statements | H300:Fatal if swallowed |
Precautionary Statements | P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. |
WGK Germany | 3 |
RTECS | VO8620000 |
1. Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, Weinberg RA, Lander ES. (2009) Identification of selective inhibitors of cancer stem cells by high-throughput screening.. Cell, 138 (4): (645-659). [PMID:19682730] |
2. Huczynski A. (2012) Salinomycin: a new cancer drug candidate.. Chem Biol Drug Des, 79 (3): (235-8). [PMID:22145602] |
3. Antoszczak M, Maj E, Napiórkowska A, Stefańska J, Augustynowicz-Kopeć E, Wietrzyk J, Janczak J, Brzezinski B, Huczyński A. (2014) Synthesis, anticancer and antibacterial activity of salinomycin N-benzyl amides.. Molecules, 19 (12): (19435-59). [PMID:25429565] |
4. Antoszczak M, Huczyński A. (2015) Anticancer Activity of Polyether Ionophore-Salinomycin.. Anticancer Agents Med Chem, 15 (5): (575-91). [PMID:25553435] |
5. Ianevski A, Yao R, Fenstad MH, Biza S, Zusinaite E, Reisberg T, Lysvand H, Løseth K, Landsem VM, Malmring JF et al.. (2020) Potential Antiviral Options against SARS-CoV-2 Infection.. Viruses, 12 (6): (589-97). [PMID:32545799] |