SANT-2 - ≥95%, high purity , CAS No.329196-48-7, Antagonist of SMO

Item Number

S275667

• Synonyms: SANT-2 | 329196-48-7 | N-[3-(1H-benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide | SANT 2 | CHEMBL514344 | N-(3-(1H-benzo[d]imidazol-2-yl)-4-chlorophenyl)-3,4,5-triethoxybenzamide | N-(3-(1H-Benzimidazol-2-yl)-4-chlorophenyl)-3,4,5-triethoxybenzamide | Oprea
• Specifications & Purity: Moligand™, ≥95%
• Biochemical and Physiological Mechanisms: Potent smoothened receptor antagonist. Allosteric modulation similar to SANT-1. Able to displace smo- [ 3 H]SAG-1.3 and [ 3 H]Cyclopamine binding (K i values are 7.8 and 8.4 nM respectively).
• Storage Temp: Protected from light,Store at -20°C,Argon charged,Desiccated
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: ANTAGONIST
• Mechanism of action: Antagonist of SMO
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.