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SKU | Size | Availability | Price | Qty |
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S126514-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $37.90 | |
S126514-20mg | 20mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $112.90 | |
S126514-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $117.90 | |
S126514-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $391.90 |
Synonyms | SAQUINAVIR [JAN] | (2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-decahydroisoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]-2-[(quinolin-2-yl)formamido]butanediamide | (S)-N-((alphaS)-alpha-((1R)-2-((3S,4AS,8AS)-3-(TERT-BUTYLCARBAMOYL)OCTAHYDRO-2( |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Saquinavir inhibits both HIV-1 and HIV-2 proteases,It is an HIV Protease Inhibitor used in antiretroviral therapy.a possible anti-cancer agent. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Human immunodeficiency virus type 1 protease inhibitor |
Product Description | Used in cell signaling and immunology studies. |
ALogP | 4.2 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Phosphodiesterase 5A inhibitor | INHIBITOR | ALA1827 | Phosphodiesterase 5A | SINGLE PROTEIN | Homo sapiens | DailyMed: [1] | |
Phosphodiesterase 5A inhibitor | INHIBITOR | ALA1827 | Phosphodiesterase 5A | SINGLE PROTEIN | Homo sapiens | DailyMed: [1] | |
Phosphodiesterase 5A inhibitor | INHIBITOR | ALA1827 | Phosphodiesterase 5A | SINGLE PROTEIN | Homo sapiens | DailyMed: [1] | |
Phosphodiesterase 5A inhibitor | INHIBITOR | ALA1827 | Phosphodiesterase 5A | SINGLE PROTEIN | Homo sapiens | FDA: [1] | |
Phosphodiesterase 5A inhibitor | INHIBITOR | ALA1827 | Phosphodiesterase 5A | SINGLE PROTEIN | Homo sapiens | PubMed: [1] | |
Phosphodiesterase 5A inhibitor | INHIBITOR | ALA1827 | Phosphodiesterase 5A | SINGLE PROTEIN | Homo sapiens | ||
Phosphodiesterase 5A inhibitor | INHIBITOR | ALA1827 | Phosphodiesterase 5A | SINGLE PROTEIN | Homo sapiens | PubMed: [1] | |
Phosphodiesterase 5A inhibitor | INHIBITOR | ALA1827 | Phosphodiesterase 5A | SINGLE PROTEIN | Homo sapiens | ||
Phosphodiesterase 5A inhibitor | INHIBITOR | ALA1827 | Phosphodiesterase 5A | SINGLE PROTEIN | Homo sapiens | PubMed: [1] | |
Epidermal growth factor receptor erbB1 inhibitor | INHIBITOR | ALA203 | Epidermal growth factor receptor erbB1 | SINGLE PROTEIN | Homo sapiens | DailyMed: [1] |
IUPAC Name | (2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]-2-(quinoline-2-carbonylamino)butanediamide |
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INCHI | InChI=1S/C38H50N6O5/c1-38(2,3)43-37(49)32-20-26-14-7-8-15-27(26)22-44(32)23-33(45)30(19-24-11-5-4-6-12-24)41-36(48)31(21-34(39)46)42-35(47)29-18-17-25-13-9-10-16-28(25)40-29/h4-6,9-13,16-18,26-27,30-33,45H,7-8,14-15,19-23H2,1-3H3,(H2,39,46)(H,41,48)(H,42,47)(H,43,49)/t26-,27+,30-,31-,32-,33+/m0/s1 |
InChi Key | QWAXKHKRTORLEM-UGJKXSETSA-N |
Canonical SMILES | CC(C)(C)NC(=O)C1CC2CCCCC2CN1CC(C(CC3=CC=CC=C3)NC(=O)C(CC(=O)N)NC(=O)C4=NC5=CC=CC=C5C=C4)O |
Isomeric SMILES | CC(C)(C)NC(=O)[C@@H]1C[C@@H]2CCCC[C@@H]2CN1C[C@H]([C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC(=O)N)NC(=O)C4=NC5=CC=CC=C5C=C4)O |
PubChem CID | 441243 |
Molecular Weight | 670.84 |
Wikipedia | Saquinavir |
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CAS Registry No. | 127779-20-8 |
DrugBank Ligand | DB01232 |
PubChem CID | 441243 |
ChEMBL Ligand | CHEMBL114 |
RCSB PDB Ligand | ROC |
DrugCentral Ligand | 2422 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
4 results found
Lot Number | Certificate Type | Date | Item |
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I2413546 | Certificate of Analysis | Apr 25, 2024 | S126514 |
I2423062 | Certificate of Analysis | Apr 25, 2024 | S126514 |
I2423066 | Certificate of Analysis | Apr 25, 2024 | S126514 |
D1912146 | Certificate of Analysis | Dec 06, 2022 | S126514 |
Solubility | DMSO |
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1. Fenglun Zhao, Zheng Xiang, Junping Han, Jie Pan, Yuchen Qu, Kai Fan, Zhiqiang Wu, Delai Xu, Yunli Yu, Zhu Shen, Cunjin Su. (2024) Simultaneous quantification of nirmatrelvir/ritonavir in human serum by LC–HRMS. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 237 (13): (115796). [PMID:37839266] [10.1016/j.jpba.2023.115796] |
2. Qing Shen, Huijuan Yang, Yunyan Li, Shiyan Li, Kang Chen, Honghai Wang, Haixing Wang, Jianfeng Ma. (2022) Rapid determination of antiviral drugs in yellow catfish (Pelteobagrus fulvidraco) using graphene/silica nanospheres (G/KCC-1) based pipette tip solid-phase extraction with ultra-performance liquid chromatography-tandem mass spectrometry. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1189 (123097). [PMID:35007897] [10.1016/j.jchromb.2022.123097] |
3. Xin Meng, Ye Wang. (2021) Drug Repurposing for Influenza Virus Polymerase Acidic (PA) Endonuclease Inhibitor. MOLECULES, 26 (23): (7326). [PMID:34885905] [10.3390/molecules26237326] |
4. Lili Wu, Wanping Zhong, Junjin Liu, Weichao Han, Shilong Zhong, Qiang Wei, Shuwen Liu, Lan Tang. (2015) Human microsomal cyttrochrome P450-mediated reduction of oxysophocarpine, an active and highly toxic constituent derived from Sophora flavescens species, and its intestinal absorption and metabolism in rat. FITOTERAPIA, 105 (26). [PMID:26045316] [10.1016/j.fitote.2015.05.021] |
1. Fenglun Zhao, Zheng Xiang, Junping Han, Jie Pan, Yuchen Qu, Kai Fan, Zhiqiang Wu, Delai Xu, Yunli Yu, Zhu Shen, Cunjin Su. (2024) Simultaneous quantification of nirmatrelvir/ritonavir in human serum by LC–HRMS. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 237 (13): (115796). [PMID:37839266] [10.1016/j.jpba.2023.115796] |
2. Qing Shen, Huijuan Yang, Yunyan Li, Shiyan Li, Kang Chen, Honghai Wang, Haixing Wang, Jianfeng Ma. (2022) Rapid determination of antiviral drugs in yellow catfish (Pelteobagrus fulvidraco) using graphene/silica nanospheres (G/KCC-1) based pipette tip solid-phase extraction with ultra-performance liquid chromatography-tandem mass spectrometry. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1189 (123097). [PMID:35007897] [10.1016/j.jchromb.2022.123097] |
3. Xin Meng, Ye Wang. (2021) Drug Repurposing for Influenza Virus Polymerase Acidic (PA) Endonuclease Inhibitor. MOLECULES, 26 (23): (7326). [PMID:34885905] [10.3390/molecules26237326] |
4. Lili Wu, Wanping Zhong, Junjin Liu, Weichao Han, Shilong Zhong, Qiang Wei, Shuwen Liu, Lan Tang. (2015) Human microsomal cyttrochrome P450-mediated reduction of oxysophocarpine, an active and highly toxic constituent derived from Sophora flavescens species, and its intestinal absorption and metabolism in rat. FITOTERAPIA, 105 (26). [PMID:26045316] [10.1016/j.fitote.2015.05.021] |