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SAR131675 - 98%, high purity , CAS No.1433953-83-3

≥98%

CAS#: 1433953-83-3
Formula: C₁₈H₂₂N₄O₄
Molecular Weight: 358.39
PubChem CID: 71295845
PubChem SID: 488202179

Item Number

S126571

Grouped product items
SKU	Size	Availability	Price
S126571-1mg	1mg	In stock	$20.90
S126571-5mg	5mg	In stock	$83.90
S126571-10mg	10mg	In stock	$137.90
S126571-25mg	25mg	In stock	$286.90
S126571-50mg	50mg	In stock	$459.90
S126571-100mg	100mg	In stock	$741.90
S126571-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,669.90

Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	VEGFR-3 is a tyrosine kinase receptor recognized by VEGF-C and VEGF-D and plays a major role in lymphangiogenesis. A number of clinical and experimental studies have demonstrated that tumor lymphangiogenesis induced by VEGFR-3 promotes me
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Associated Targets(Human)

FLT4 Tclin Vascular endothelial growth factor receptor 3 (1 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FLT4 Tclin Vascular endothelial growth factor receptor 3 (3216 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FLT3 Tclin Tyrosine-protein kinase receptor FLT3 (13481 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HUVEC (11049 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MDA-MB-231 (73002 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MDA-MB-436 (532 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BaF3 (4657 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

Pubchem Sid	488202179
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488202179
IUPAC Name	2-amino-1-ethyl-7-[(3R)-3-hydroxy-4-methoxy-3-methylbut-1-ynyl]-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide
INCHI	InChI=1S/C18H22N4O4/c1-5-22-15(19)13(17(24)20-3)14(23)12-7-6-11(21-16(12)22)8-9-18(2,25)10-26-4/h6-7,25H,5,10,19H2,1-4H3,(H,20,24)/t18-/m1/s1
InChi Key	PFMPOBVAYMTUOX-GOSISDBHSA-N
Canonical SMILES	CCN1C(=C(C(=O)C2=C1N=C(C=C2)C#CC(C)(COC)O)C(=O)NC)N
Isomeric SMILES	CCN1C(=C(C(=O)C2=C1N=C(C=C2)C#C[C@](C)(COC)O)C(=O)NC)N
PubChem CID	71295845
Molecular Weight	358.39

Certificates

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15 results found

Lot Number	Certificate Type	Date	Item
A2205435	Certificate of Analysis	Oct 10, 2023	S126571
A2205439	Certificate of Analysis	Oct 10, 2023	S126571
A2205440	Certificate of Analysis	Oct 10, 2023	S126571
A2205441	Certificate of Analysis	Oct 10, 2023	S126571
A2205522	Certificate of Analysis	Oct 10, 2023	S126571
A2205523	Certificate of Analysis	Oct 10, 2023	S126571
C23241400	Certificate of Analysis	Jan 16, 2023	S126571
C23241403	Certificate of Analysis	Jan 16, 2023	S126571
C23241404	Certificate of Analysis	Jan 16, 2023	S126571
C23241406	Certificate of Analysis	Jan 16, 2023	S126571
C23241477	Certificate of Analysis	Jan 16, 2023	S126571
C23241481	Certificate of Analysis	Jan 16, 2023	S126571
C23241482	Certificate of Analysis	Jan 16, 2023	S126571
C23241483	Certificate of Analysis	Jan 16, 2023	S126571
C23241484	Certificate of Analysis	Jan 16, 2023	S126571

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SAR131675 - 98%, high purity , CAS No.1433953-83-3

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

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