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SD-208 - ≥98%, high purity , CAS No.627536-09-8, Inhibitor of transforming growth factor beta receptor 1

Specifications & Purity: ≥98%

CAS#: 627536-09-8
Formula: C₁₇H₁₀ClFN₆
Molecular Weight: 352.75
MDL number: MFCD11519969
PubChem CID: 10316032

Item Number

S125587

Grouped product items
SKU	Size	Availability	Price
S125587-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$9.90
S125587-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$37.90
S125587-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$123.90

Potent ATP-competitive TGF-βRI inhibitor

View related series

transforming growth factor beta receptor 1 Inhibitor

Basic Description

Synonyms	SD-208\|627536-09-8\|SD208\|SD 208\|2-(5-chloro-2-fluorophenyl)-N-(pyridin-4-yl)pteridin-4-amine\|2-(5-chloro-2-fluorophenyl)-N-pyridin-4-ylpteridin-4-amine\|CHEMBL238125\|ALK5 Inhibitor V\|2-(5-Chloro-2-fluorophenyl)-4-[(4-pyridyl)amino]pteridine\|2-(5-chloro-2-f
Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Dry ice
Action Type	INHIBITOR
Mechanism of action	Inhibitor of transforming growth factor beta receptor 1

Names and Identifiers

IUPAC Name	2-(5-chloro-2-fluorophenyl)-N-pyridin-4-ylpteridin-4-amine
INCHI	InChI=1S/C17H10ClFN6/c18-10-1-2-13(19)12(9-10)15-24-16-14(21-7-8-22-16)17(25-15)23-11-3-5-20-6-4-11/h1-9H,(H,20,22,23,24,25)
InChi Key	BERLXWPRSBJFHO-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=C(C=C1Cl)C2=NC3=NC=CN=C3C(=N2)NC4=CC=NC=C4)F
Isomeric SMILES	C1=CC(=C(C=C1Cl)C2=NC3=NC=CN=C3C(=N2)NC4=CC=NC=C4)F
WGK Germany	3
PubChem CID	10316032
Molecular Weight	352.75

CAS Registry No.

627536-09-8

PubChem CID

10316032

ChEMBL Ligand

CHEMBL238125

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Certificate of Analysis(COA)

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Lot Number	Certificate Type	Date	Item
E1718066	Certificate of Analysis	Jan 11, 2023	S125587

Solubility

Solvent:DMSO, Max Conc. mg/mL: 7.05, Max Conc. mM: 20 with gentle warming

Refractive Index

1.72

Boil Point(°C)

460.41° C at 760 mmHg

Melt Point(°C)

214.79°C

Pictogram(s)

GHS07

Signal

Warning

Hazard Statements

H302

Precautionary Statements

P501,P264,P270,P330,P301+P317

WGK Germany

References

1. Raboisson P, Lenz O, Lin TI, Surleraux D, Chakravarty S, Scholliers A, Vermeiren K, Delouvroy F, Verbinnen T, Simmen K. (2007) Evaluation of the anti-hepatitis C virus effect of novel potent, selective, and orally bioavailable JNK and VEGFR kinase inhibitors.. Bioorg Med Chem Lett, 17 (7): (1843-9). [PMID:17289388]

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SD-208 - ≥98%, high purity , CAS No.627536-09-8, Inhibitor of transforming growth factor beta receptor 1

Basic Description

Associated Targets

TGFBR1 Tchem TGF-beta receptor type-1 1 Activities

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

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References

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