Basic Description

Synonyms	SECLIDEMSTAT [WHO-DD] \| BDBM50590443 \| SECLIDEMSTAT [USAN] \| 1423715-37-0 \| NSC833973 \| NSC-833973 \| TYH386V3WJ \| SCHEMBL14697017 \| Benzoic acid, 3-[(4-methyl-1-piperazinyl)sulfonyl]-, (2E)-2-[1-(5-chloro-2-hydroxyphenyl)ethylidene]hydrazide \| YGC71537 \|
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Seclidemstat (SP-2577) is a potent and orally bioavailable inhibitor of lysine-specific demethylase 1 (LSD1/KDM1A) with IC50 of 127 nM. Seclidemstat (SP-2577) has potential antineoplastic activity.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Product Properties

KDM1A Tchem Lysine-specific histone demethylase 1 (3916 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Pubchem Sid	488202969
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488202969
IUPAC Name	N-[(E)-1-(5-chloro-2-hydroxyphenyl)ethylideneamino]-3-(4-methylpiperazin-1-yl)sulfonylbenzamide
INCHI	InChI=1S/C20H23ClN4O4S/c1-14(18-13-16(21)6-7-19(18)26)22-23-20(27)15-4-3-5-17(12-15)30(28,29)25-10-8-24(2)9-11-25/h3-7,12-13,26H,8-11H2,1-2H3,(H,23,27)/b22-14+
InChi Key	MVSQDUZRRVBYLA-HYARGMPZSA-N
Canonical SMILES	CC(=NNC(=O)C1=CC(=CC=C1)S(=O)(=O)N2CCN(CC2)C)C3=C(C=CC(=C3)Cl)O
Isomeric SMILES	C/C(=N\NC(=O)C1=CC(=CC=C1)S(=O)(=O)N2CCN(CC2)C)/C3=C(C=CC(=C3)Cl)O
PubChem CID	135565033
Molecular Weight	450.94

Enter Lot Number to search for COA:

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12 results found

Lot Number	Certificate Type	Date	Item
C2320174	Certificate of Analysis	Dec 19, 2022	S413599
C2320175	Certificate of Analysis	Dec 19, 2022	S413599
C2320183	Certificate of Analysis	Dec 19, 2022	S413599
C2320184	Certificate of Analysis	Dec 19, 2022	S413599
C2320211	Certificate of Analysis	Dec 19, 2022	S413599
C2320222	Certificate of Analysis	Dec 19, 2022	S413599
C2320223	Certificate of Analysis	Dec 19, 2022	S413599
C2320225	Certificate of Analysis	Dec 19, 2022	S413599
C2320232	Certificate of Analysis	Dec 19, 2022	S413599
C2320233	Certificate of Analysis	Dec 19, 2022	S413599
C2320235	Certificate of Analysis	Dec 19, 2022	S413599
C2320250	Certificate of Analysis	Dec 19, 2022	S413599

Solubility	Solubility (25°C) In vitro DMSO: 90 mg/mL (199.58 mM); Water: ˂1 mg/mL Ethanol: ˂1 mg/mL
DMSO(mg / mL) Max Solubility	90
DMSO(mM) Max Solubility	199.583093094425
Water(mg / mL) Max Solubility	˂1

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SKU	Size	Availability	Price
S413599-5mg	5mg	In stock	$48.90
S413599-10mg	10mg	In stock	$78.90
S413599-25mg	25mg	In stock	$147.90
S413599-50mg	50mg	In stock	$246.90
S413599-100mg	100mg	In stock	$444.90
S413599-200mg	200mg	In stock	$801.90