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Seclidemstat (SP-2577) - 10mM in DMSO, high purity , CAS No.1423715-37-0

Item Number

S421570

Grouped product items
SKU	Size	Availability	Price	Qty
S421570-1ml	1ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$241.90

LSD1 Inhibitors

Basic Description

Synonyms	SECLIDEMSTAT [WHO-DD] \| BDBM50590443 \| SECLIDEMSTAT [USAN] \| 1423715-37-0 \| NSC833973 \| NSC-833973 \| TYH386V3WJ \| SCHEMBL14697017 \| Benzoic acid, 3-[(4-methyl-1-piperazinyl)sulfonyl]-, (2E)-2-[1-(5-chloro-2-hydroxyphenyl)ethylidene]hydrazide \| YGC71537 \|
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	Seclidemstat (SP-2577) is a potent and orally bioavailable inhibitor of lysine-specific demethylase 1 (LSD1/KDM1A) with IC50 of 127 nM. Seclidemstat (SP-2577) has potential antineoplastic activity.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	Information Seclidemstat (SP-2577) Seclidemstat (SP-2577) is a potent and orally bioavailable inhibitor of lysine-specific demethylase 1 (LSD1/KDM1A) with IC50 of 127 nM. Seclidemstat (SP-2577) has potential antineoplastic activity. Targets LSD1/KDM1A (Cell-free assay) 127 nM

KDM1A Tchem Lysine-specific histone demethylase 1 (3916 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

IUPAC Name	N-[(E)-1-(5-chloro-2-hydroxyphenyl)ethylideneamino]-3-(4-methylpiperazin-1-yl)sulfonylbenzamide
INCHI	InChI=1S/C20H23ClN4O4S/c1-14(18-13-16(21)6-7-19(18)26)22-23-20(27)15-4-3-5-17(12-15)30(28,29)25-10-8-24(2)9-11-25/h3-7,12-13,26H,8-11H2,1-2H3,(H,23,27)/b22-14+
InChi Key	MVSQDUZRRVBYLA-HYARGMPZSA-N
Canonical SMILES	CC(=NNC(=O)C1=CC(=CC=C1)S(=O)(=O)N2CCN(CC2)C)C3=C(C=CC(=C3)Cl)O
Isomeric SMILES	C/C(=N\NC(=O)C1=CC(=CC=C1)S(=O)(=O)N2CCN(CC2)C)/C3=C(C=CC(=C3)Cl)O
PubChem CID	135565033
Molecular Weight	450.94

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