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selegiline , Monoamine oxidase B inhibitor, CAS No.14611-51-9, Monoamine oxidase B inhibitor
Basic Description Synonyms selegiline|L-Deprenalin|Emsam|(-)-selegiline|14611-51-9|L-Deprenyl|Eldepryl|selgene|Selegilina|Selegilinum|Zelapar|(-)-Deprenil|Jumex|Zalapar|L-Selegiline|Selegilinum [INN-Latin]|Selegilina [INN-Spanish]|Anipryl|Otrasel|Selegene|(R)-(-)-Selegiline|l-E 250 Specifications & Purity Moligand™, ≥98% Biochemical and Physiological Mechanisms Selegiline (Deprenyl) is a potent, selective and irreversible inhibitor of MAO-B, with an IC50 of 51 nM. Selegiline exhibits 450-flod selectivity for MAO-B over MAO-A (IC50=23 μM). Selegiline can be used for the research of Parkinson's disease, Alzheimer' Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type INHIBITOR Mechanism of action Monoamine oxidase B inhibitor
Names and Identifiers IUPAC Name (2R)-N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine INCHI InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1 InChi Key MEZLKOACVSPNER-GFCCVEGCSA-N Canonical SMILES CC(CC1=CC=CC=C1)N(C)CC#C Isomeric SMILES C[C@H](CC1=CC=CC=C1)N(C)CC#C Alternate CAS 14611-51-9,2079-54-1 (deprenyl.hydrochloride) PubChem CID 26757 MeSH Entry Terms Deprenalin;Deprenil;Deprenyl;E 250;E-250;E250;Eldepryl;Emsam;Humex;Jumex;L-Deprenyl;Selegiline;Selegiline Hydrochloride;Selegiline Hydrochloride, (R)-Isomer;Selegiline Hydrochloride, (R,S)-Isomer;Selegiline Hydrochloride, (S)-Isomer;Selegiline, (R)-Isomer Molecular Weight 187.28
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