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semapimod , MAP kinase p38 alpha inhibitor, CAS No.352513-83-8, MAP kinase p38 alpha inhibitor

semapimod , MAP kinase p38 alpha inhibitor, CAS No.352513-83-8, MAP kinase p38 alpha inhibitor

Item Number

S613530

Grouped product items
SKU	Size	Availability	Price	Qty
S613530-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$570.90
S613530-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Basic Description

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

INCHI	InChI=1S/C34H52N18O2/c1-19(45-49-31(35)36)23-13-24(20(2)46-50-32(37)38)16-27(15-23)43-29(53)11-9-7-5-6-8-10-12-30(54)44-28-17-25(21(3)47-51-33(39)40)14-26(18-28)22(4)48-52-34(41)42/h13-18H,5-12H2,1-4H3,(H,43,53)(H,44,54)(H4,35,36,49)(H4,37,38,50)(H4,39,40,51)(H4,41,42,52)/b45-19-,46-20+,47-21-,48-22+
InChi Key	PWDYHMBTPGXCSN-BFKCERSTSA-N
Canonical SMILES	O=C(Nc1cc(cc(c1)/C(=N\N=C(N)N)/C)/C(=N/N=C(N)N)/C)CCCCCCCCC(=O)Nc1cc(cc(c1)/C(=N\N=C(N)N)/C)/C(=N/N=C(N)N)/C
Isomeric SMILES	C/C(=N/N=C(N)N)/C1=CC(=CC(=C1)NC(=O)CCCCCCCCC(=O)NC2=CC(=CC(=C2)/C(=N/N=C(N)N)/C)/C(=N\N=C(N)N)/C)/C(=N/N=C(N)N)/C
PubChem CID	9854289

PubChem CID	9854289
CAS Registry No.	352513-83-8

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1. Wang J, Grishin AV, Ford HR. (2016) Experimental Anti-Inflammatory Drug Semapimod Inhibits TLR Signaling by Targeting the TLR Chaperone gp96.. J Immunol, 196 (12): (5130-7). [PMID:27194788]

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