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Home Microbiology Sertaconazole nitrate - ≥98%, high purity , Cytochrome P450 51 inhibitor, CAS No.99592-39-9, Cytochrome P450 51 inhibitor
Sertaconazole nitrate - ≥98%, high purity , Cytochrome P450 51 inhibitor, CAS No.99592-39-9, Cytochrome P450 51 inhibitor
Basic Description Synonyms HMS1571A12 | CAS-99592-39-9 | A851341 | 1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole; nitric acid | Onabet | rac-1-(2-((7-chloro-1-benzothiophen-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate | S Specifications & Purity ≥98% Biochemical and Physiological Mechanisms Sertaconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fungal cell membrane, inhibition of its synthesis results in increased cellular perm Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Action Type INHIBITOR Mechanism of action Cytochrome P450 51 inhibitor Note 卖完停产，不再备货
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers Pubchem Sid 488188600 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488188600 IUPAC Name 1-[2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole;nitric acid INCHI InChI=1S/C20H15Cl3N2OS.HNO3/c21-14-4-5-16(18(23)8-14)19(9-25-7-6-24-12-25)26-10-13-11-27-20-15(13)2-1-3-17(20)22;2-1(3)4/h1-8,11-12,19H,9-10H2;(H,2,3,4) InChi Key HAAITRDZHUANGT-UHFFFAOYSA-N Canonical SMILES C1=CC2=C(C(=C1)Cl)SC=C2COC(CN3C=CN=C3)C4=C(C=C(C=C4)Cl)Cl.[N+](=O)(O)[O-] Isomeric SMILES C1=CC2=C(C(=C1)Cl)SC=C2COC(CN3C=CN=C3)C4=C(C=C(C=C4)Cl)Cl.[N+](=O)(O)[O-] WGK Germany 3 PubChem CID 200103 Molecular Weight 500.78
Chemical and Physical Properties Solubility Soluble in DMSO (20 mg/ml), and methanol. Melt Point(°C) 163-165°C
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D2321186