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| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Basic Description
| Synonyms | Sesamol | 533-31-3 | 1,3-Benzodioxol-5-ol | 3,4-Methylenedioxyphenol | 3,4-(Methylenedioxy)phenol | 5-Hydroxy-1,3-benzodioxole | 3,4-Methylendioxyphenol | Methylene ether of oxyhydroquinone | Phenol, 3,4-(methylenedioxy)- | benzo[d][1,3]dioxol-5-ol | 2H-1,3-Benzodioxol-5-Ol | |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Storage Temp | Protected from light,Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | application： Sesamol has good antioxidant activity. Sesamol has potential protective effects against free radicals as well as some antifungal activity. Sesamol can also be used as an intermediate in the preparation of antidepressants such as Paroxetine (P205750). Sesamol has been found to be an antioxidant that may prevent the spoilage of oils. It also may prevent the spoilage of oils by acting as an antifungal. It is also used in ayurvedic Medicine. |
Associated Targets(Human)
CYP3A4 Tclin Cytochrome P450 3A4 (0 Activities)
MAPK12 Tchem Mitogen-activated protein kinase 12 (0 Activities)
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AR Tclin Androgen receptor (0 Activities)
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PPARG Tclin Peroxisome proliferator-activated receptor gamma (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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OLR1 Tbio Oxidized low-density lipoprotein receptor 1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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NOS3 Tchem Nitric oxide synthase, endothelial (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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AR Tclin Androgen Receptor (11781 Activities)
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TYR Tclin Tyrosinase (717 Activities)
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PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
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NOS3 Tchem Nitric-oxide synthase, endothelial (1452 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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HEK293 (82097 Activities)
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MAPK13 Tchem MAP kinase p38 (1586 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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OLR1 Tbio Oxidized low-density lipoprotein receptor 1 (2 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Associated Targets(non-human)
pol Human immunodeficiency virus type 1 integrase (9041 Activities)
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Syrian golden hamster (1610 Activities)
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Names and Identifiers
| IUPAC Name | 1,3-benzodioxol-5-ol |
|---|---|
| INCHI | InChI=1S/C7H6O3/c8-5-1-2-6-7(3-5)10-4-9-6/h1-3,8H,4H2 |
| InChi Key | LUSZGTFNYDARNI-UHFFFAOYSA-N |
| Canonical SMILES | C1OC2=C(O1)C=C(C=C2)O |
| Isomeric SMILES | C1OC2=C(O1)C=C(C=C2)O |
| WGK Germany | 3 |
| RTECS | SM0890000 |
| PubChem CID | 68289 |
| Molecular Weight | 138.12 |
| Beilstein | 127405 |
| Reaxy-Rn | 127405 |
Certificates
Certificate of Analysis(COA)
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Chemical and Physical Properties
| Sensitivity | Sensitive to light; sensitive to air |
|---|---|
| Boil Point(°C) | 113°C/2mmHg |
| Melt Point(°C) | 63-65°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS08, GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H373:Causes damage to organs through prolonged or repeated exposure |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 3 |
| RTECS | SM0890000 |
| Reaxy-Rn | 127405 |
Related Documents
Citations of This Product
| 1. Saisai Feng, Liping Liu, Huanyang Li, Yan Guo, Yanxiong Huo, Xiaojiang Wu, Liangliang Zhang, Jianguo Xu. (2024) Characterization, antioxidant and antibacterial activities of chitosan/flaxseed soluble dietary fiber/sesamol blend films and their application in pork preservation. FOOD HYDROCOLLOIDS, 147 (31): (109370). [PMID:24687277] |
| 2. Wenqian Zhao, Beibei Chen, Kan Zhang. (2022) Biobased Bisbenzoxazine Resins Derived from Natural Renewable Monophenols and Diamine: Synthesis and Property Investigations. ACS Sustainable Chemistry & Engineering, 10 (45): (14783–14793). [PMID:] |
References
| 1. Saisai Feng, Liping Liu, Huanyang Li, Yan Guo, Yanxiong Huo, Xiaojiang Wu, Liangliang Zhang, Jianguo Xu. (2024) Characterization, antioxidant and antibacterial activities of chitosan/flaxseed soluble dietary fiber/sesamol blend films and their application in pork preservation. FOOD HYDROCOLLOIDS, 147 (31): (109370). [PMID:24687277] |
| 2. Wenqian Zhao, Beibei Chen, Kan Zhang. (2022) Biobased Bisbenzoxazine Resins Derived from Natural Renewable Monophenols and Diamine: Synthesis and Property Investigations. ACS Sustainable Chemistry & Engineering, 10 (45): (14783–14793). [PMID:] |