setogepram , G-protein coupled receptor 84 antagonist, CAS No.1002101-19-0, G-protein coupled receptor 84 antagonist

Item Number

S613548

Grouped product items
SKU	Size	Availability	Price	Qty
S613548-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
S613548-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,001.90

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Basic Description

Synonyms	2-(3-Pentylphenyl)acetic acid \| 1002101-19-0 (free acid) \| BDBM50548388 \| setogepram \| DB15447 \| HY-100775A \| CS-0062694 \| 1002101-19-0 \| AKOS028113459 \| Benzeneacetic acid, 3-pentyl- \| Z1508932704 \| EN300-1168886 \| CQB10119 \| 2-(3-Pentylphenyl)aceticacid
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	AGONIST, ANTAGONIST
Mechanism of action	G-protein coupled receptor 84 antagonist

Associated Targets(Human)

GPR84 Tchem G-protein coupled receptor 84 (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FFAR1 Tchem Free fatty acid receptor 1 (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	2-(3-pentylphenyl)acetic acid
INCHI	InChI=1S/C13H18O2/c1-2-3-4-6-11-7-5-8-12(9-11)10-13(14)15/h5,7-9H,2-4,6,10H2,1H3,(H,14,15)
InChi Key	PEGQOIGYZLJMIB-UHFFFAOYSA-N
Canonical SMILES	CCCCCc1cccc(c1)CC(=O)O
Isomeric SMILES	CCCCCC1=CC(=CC=C1)CC(=O)O
PubChem CID	24749700
Molecular Weight	206.28

PubChem CID

CAS Registry No.

GPCRdb Ligand

References

1. Gagnon L, Leduc M, Thibodeau JF, Zhang MZ, Grouix B, Sarra-Bournet F, Gagnon W, Hince K, Tremblay M, Geerts L et al.. (2018) A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84.. Am J Pathol, 188 (5): (1132-1148). [PMID:29454750] [10.1021/op500134e]
2. Li Y, Chung S, Li Z, Overstreet JM, Gagnon L, Grouix B, Leduc M, Laurin P, Zhang MZ, Harris RC. (2018) Fatty acid receptor modulator PBI-4050 inhibits kidney fibrosis and improves glycemic control.. JCI Insight, 3 (10): (1755-70). [PMID:29769449] [10.1021/op500134e]

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Basic Description