The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
SH-5 - ≥98%, high purity , CAS No.9938589
an Inhibitor of Akt activation
Basic Description Synonyms Akt Inhibitor II; D-3-Deoxy-2-O-methyl-myo-inositol 1-[(R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate] Specifications & Purity ≥98% Storage Temp Store at 2-8°C Shipped In Wet ice Product Description SH-5 is an inhibitor of Akt (PKB) activation without affecting activation of the upstream kinase PDK-1, or other kinases downstream of Ras such as MAPK. SH-5 induces apoptosis and kills a variety of cancer cell lines containing high levels of active Akt and depending upon Akt for survival. SH-5 is an activator of p38 alpha.
Names and Identifiers Canonical SMILES CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)O[C@@H]1[C@@H](C[C@H]([C@@H]([C@H]1O)O)O)OC)OC Isomeric SMILES CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)O[C@@H]1[C@@H](C[C@H]([C@@H]([C@H]1O)O)O)OC)OC PubChem CID 9938589 Molecular Weight 598.75
Chemical and Physical Properties Solubility Soluble in DMSO (10 mg/ml), methanol, and water (slightly). Refractive Index n20D1.50 (Predicted) Boil Point(°C) ~670.3° C at 760 mmHg (Predicted)
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
