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SH-5 - ≥98%, high purity , CAS No.9938589
an Inhibitor of Akt activation
Basic Description Specifications & Purity ≥98% Storage Temp Store at 2-8°C Shipped In Wet ice Product Description SH-5 is an inhibitor of Akt (PKB) activation without affecting activation of the upstream kinase PDK-1, or other kinases downstream of Ras such as MAPK. SH-5 induces apoptosis and kills a variety of cancer cell lines containing high levels of active Akt and depending upon Akt for survival. SH-5 is an activator of p38 alpha.
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers Canonical SMILES CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)O[C@@H]1[C@@H](C[C@H]([C@@H]([C@H]1O)O)O)OC)OC Isomeric SMILES CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)O[C@@H]1[C@@H](C[C@H]([C@@H]([C@H]1O)O)O)OC)OC PubChem CID 9938589 Molecular Weight 598.75
Chemical and Physical Properties Solubility Soluble in DMSO (10 mg/ml), methanol, and water (slightly). Refractive Index n20D1.50 (Predicted) Boil Point(°C) ~670.3° C at 760 mmHg (Predicted)
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