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SH-5 - ≥98%, high purity , CAS No.9938589
an Inhibitor of Akt activation
Basic Description Specifications & Purity ≥98% Storage Temp Store at 2-8°C Shipped In Wet ice Product Description SH-5 is an inhibitor of Akt (PKB) activation without affecting activation of the upstream kinase PDK-1, or other kinases downstream of Ras such as MAPK. SH-5 induces apoptosis and kills a variety of cancer cell lines containing high levels of active Akt and depending upon Akt for survival. SH-5 is an activator of p38 alpha.
Associated Targets(Human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers Canonical SMILES CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)O[C@@H]1[C@@H](C[C@H]([C@@H]([C@H]1O)O)O)OC)OC Isomeric SMILES CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)O[C@@H]1[C@@H](C[C@H]([C@@H]([C@H]1O)O)O)OC)OC PubChem CID 9938589 Molecular Weight 598.75
Chemical and Physical Properties Solubility Soluble in DMSO (10 mg/ml), methanol, and water (slightly). Refractive Index n20D1.50 (Predicted) Boil Point(°C) ~670.3° C at 760 mmHg (Predicted)
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