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SHBG Mouse mAb - Primary antibody, specific to SHBG, Mouse IgG1

  • Azide Free
  • Carrier Free
  • ExactAb™
  • Validated
  • Lot by Lot
Features and benefits
  • Short Overview:

    mAb(3E10-1); Mouse anti Human SHBG Antibody; Capture Antibody, ELISA, CLIA, LF, GICA, FIA; Unconjugated

  • Species reactivity(Reacts with): Human
  • Isotype: Mouse IgG1
    Application:
  • Capture Antibody
  • CLIA
  • ELISA
  • FIA
  • GICA
  • LF
Item Number
Ab005505
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab005505-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$66.90
Ab005505-50μg
50μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$199.90
Ab005505-100μg
100μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$319.90
Ab005505-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$999.90

mAb(3E10-1); Mouse anti Human SHBG Antibody; Capture Antibody, ELISA, CLIA, LF, GICA, FIA; Unconjugated

View related series
Accession#:P04278 Gene ID:6462 SHBG

Basic Description

Product NameSHBG Mouse mAb - Primary antibody, specific to SHBG, Mouse IgG1
SynonymsABP antibody; Androgen binding protein antibody; SBP antibody; Sex hormone-binding globulin antibody; Sex steroid binding protein antibody; Sex steroid-binding protein antibody; SHBG antibody; SHBG_HUMAN antibody; TeBG antibody; Testis specific androgen b
Specifications & PurityExactAb™, Validated, Carrier Free, Azide Free, Lot by Lot
Host speciesMouse
SpecificitySHBG
ImmunogenRecombinant Human SHBG protein
ConjugationUnconjugated
GradeAzide Free, Carrier Free, ExactAb™, Validated
Product Description

Mouse anti Human SHBG Antibody, Monoclonal (3E10-1), Capture antibody, could be used for ELISA, CLIA, LF, GICA, FIA.
CLIA:20ug/2mg
FIA:1mg/mL

Product Properties

IsotypeMouse IgG1
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodAffinity chromatography
Matched Pairs[Ab005506] Monoclonal Human SHBG Antibody as Detection antibody in ELISA, CLIA, LF, GICA, FIA
FormLiquid
ConcentrationLot by Lot
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 2-8°C short term (30 days). Store at -20°C long term (36 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Sandwich ELISA - SHBG protein standard curve
SHBG protein was serially diluted 4-fold and captured by SHBG Mouse mAb (Ab005505) coated on a Clear Polystyrene Microplate (W291037). SHBG Mouse mAb (Ab005514) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (np156148).

Relevance of detection results between aladdin Antibody Pair (Ab005505 & Ab005514) and Beckman Coulter in CLIA
·Capture antibody: SHBG Mouse mAb (Ab005505)
·Detection antibody: SHBG Mouse mAb (Ab005514)

Binding ELISA - SHBG Mouse mAb (Ab005505)
Immobilized Recombinant Human SHBG Protein at 1.0 μg/mL can bind SHBG Mouse mAb (Ab005505) with the EC₅₀ of 11.47 ng/mL.




Associated Targets

SHBG Tchem Sex hormone-binding globulin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
FIA

1 mg/mL

CLIA

20ug/2mg

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot NumberCertificate TypeDateItem
ZJ23F1001364Certificate of AnalysisOct 19, 2023 Ab005505
ZJ23F1001363Certificate of AnalysisOct 19, 2023 Ab005505

Related Documents

References

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2. Liu A, Carlson KE, Katzenellenbogen JA..  (1992)  Synthesis of high affinity fluorine-substituted ligands for the androgen receptor. Potential agents for imaging prostatic cancer by positron emission tomography..  J Med Chem,  35  (11): (2113-2129).  [PMID:1597861]
3. Choe YS, Lidström PJ, Chi DY, Bonasera TA, Welch MJ, Katzenellenbogen JA..  (1995)  Synthesis of 11 beta-[18F]fluoro-5 alpha-dihydrotestosterone and 11 beta-[18F]fluoro-19-nor-5 alpha-dihydrotestosterone: preparation via halofluorination-reduction, receptor binding, and tissue distribution..  J Med Chem,  38  (5): (816-825).  [PMID:7877147]
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6. Gershagen, S S, Lundwall, A A and Fernlund, P P..  (1989)  Characterization of the human sex hormone binding globulin (SHBG) gene and demonstration of two transcripts in both liver and testis..  Nucleic acids research,    (25):   [PMID:2587256]
7. Hammond, G L GL, Underhill, D A DA, Rykse, H M HM and Smith, C L CL..  (1989)  The human sex hormone-binding globulin gene contains exons for androgen-binding protein and two other testicular messenger RNAs..  Molecular endocrinology (Baltimore, Md.),      [PMID:2608061]
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10. Walsh, K A KA and 5 more authors..  (1986)  Amino acid sequence of the sex steroid binding protein of human blood plasma..  Biochemistry,    (18):   [PMID:3542030]
11. Hammond, G L GL and 7 more authors..  (1987)  The cDNA-deduced primary structure of human sex hormone-binding globulin and location of its steroid-binding domain..  FEBS letters,    (4):   [PMID:3569533]
12. Hammond, G L GL, Robinson, P A PA, Sugino, H H, Ward, D N DN and Finne, J J..  (1986)  Physicochemical characteristics of human sex hormone binding globulin: evidence for two identical subunits..  Journal of steroid biochemistry,      [PMID:3702459]
13. Hardy, D O DO, Cariño, C C, Catterall, J F JF and Larrea, F F..  (1995)  Molecular characterization of a genetic variant of the steroid hormone-binding globulin gene in heterozygous subjects..  The Journal of clinical endocrinology and metabolism,      [PMID:7714097]
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15. Grishkovskaya, I I and 5 more authors..  (2000)  Crystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain..  The EMBO journal,    (15):   [PMID:10675319]
16. Hammond, G L GL, Rabe, T T and Wagner, J D JD..  (2001)  Preclinical profiles of progestins used in formulations of oral contraceptives and hormone replacement therapy..  American journal of obstetrics and gynecology,      [PMID:11521119]
17. Grishkovskaya, Irina I, Avvakumov, George V GV, Hammond, Geoffrey L GL, Catalano, Maria G MG and Muller, Yves A YA..  (2002)  Steroid ligands bind human sex hormone-binding globulin in specific orientations and produce distinct changes in protein conformation..  The Journal of biological chemistry,    (30):   [PMID:12065592]
18. Jin, Pei P and 7 more authors..  (2004)  PCR isolation and cloning of novel splice variant mRNAs from known drug target genes..  Genomics,      [PMID:15028279]
19. Liu, Tao T and 6 more authors..  ()  Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry..  Journal of proteome research,      [PMID:16335952]
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