The store will not work correctly when cookies are disabled.
SID 7969543 - 98%, high purity , CAS No.868224-64-0
Selective steroidogenic factor-1 (SF-1, NR5A1) inhibitor
Basic Description
| Synonyms | HY-107404 | MS-28223 | SID 7969543 | ETHYL 2-[[2-[2-[(2,3-DIHYDRO-BENZO[B][1,4]DIOXINE-6-YL)AMINO]-2-OXOETHYL]-1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL]OXY]PROPANOATE | ethyl 2-[(2-{[(2,3-dihydro-1,4-benzodioxin-6-yl)carbamoyl]methyl}-1-oxo-1,2-dihydroisoquinoli |
|---|
| Specifications & Purity | Moligand™, ≥98% |
|---|
| Biochemical and Physiological Mechanisms | Selective steroidogenic factor-1 (SF-1, NR5A1) inhibitor (IC50values are 0.76, >33 and >33μM at SF-1, RORαand VP16 respectively). Inhibits SF-1-dependent luciferase expression in HEK 293T cellsin vitro(IC50= 30 nM). |
|---|
| Storage Temp | Store at -20°C |
|---|
| Shipped In | Ice chest + Ice pads |
|---|
| Grade | Moligand™ |
|---|
Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| IUPAC Name | ethyl 2-[2-[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxypropanoate |
|---|
| INCHI | InChI=1S/C24H24N2O7/c1-3-30-24(29)15(2)33-19-6-4-5-18-17(19)9-10-26(23(18)28)14-22(27)25-16-7-8-20-21(13-16)32-12-11-31-20/h4-10,13,15H,3,11-12,14H2,1-2H3,(H,25,27) |
|---|
| InChi Key | KWMBIIQCLUIHDI-UHFFFAOYSA-N |
|---|
| Canonical SMILES | CCOC(=O)C(C)OC1=CC=CC2=C1C=CN(C2=O)CC(=O)NC3=CC4=C(C=C3)OCCO4 |
|---|
| Isomeric SMILES | CCOC(=O)C(C)OC1=CC=CC2=C1C=CN(C2=O)CC(=O)NC3=CC4=C(C=C3)OCCO4 |
|---|
| WGK Germany | 3 |
|---|
| PubChem CID | 4076092 |
|---|
| Molecular Weight | 452.46 |
|---|
Chemical and Physical Properties
| Solubility | Solvent:DMSO, Max Conc. mg/mL: 45.25, Max Conc. mM: 100 |
|---|
Safety and Hazards(GHS)
| WGK Germany | 3 |
|---|
| RIDADR | NONHforallmodesoftransport |
|---|
Solution Calculators
Molarity Calculator
Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator
Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
H2303799