The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
Sipatrigine - ≥99%(HPLC), high purity , CAS No.130800-90-7
NaVblocker; neuroprotective
Basic Description Synonyms Sipatrigine | SIPATRIGINE [INN] | SIPATRIGINE [WHO-DD] | BDBM50066430 | BW619C89 | SCHEMBL135888 | OON9AVW1T3 | 2-(4-Methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-4-pyrimidinamine | 2-(4-methylpiperazin-1-yl)-5-(2,3,5-trichlorophenyl)pyrimidin-4-amine | Specifications & Purity ≥99%(HPLC) Biochemical and Physiological Mechanisms Blocker of voltage-dependent sodium channels (NaV). Inhibits glutamate release; displays neuroprotective activity in rat models of cerebral ischemia. Also thought to block Ca2+channels. Analog of lamotrigine. Storage Temp Room temperature Shipped In Normal
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name 2-(4-methylpiperazin-1-yl)-5-(2,3,5-trichlorophenyl)pyrimidin-4-amine INCHI InChI=1S/C15H16Cl3N5/c1-22-2-4-23(5-3-22)15-20-8-11(14(19)21-15)10-6-9(16)7-12(17)13(10)18/h6-8H,2-5H2,1H3,(H2,19,20,21) InChi Key PDOCBJADCWMDGL-UHFFFAOYSA-N Canonical SMILES CN1CCN(CC1)C2=NC=C(C(=N2)N)C3=C(C(=CC(=C3)Cl)Cl)Cl Isomeric SMILES CN1CCN(CC1)C2=NC=C(C(=N2)N)C3=C(C(=CC(=C3)Cl)Cl)Cl PubChem CID 60803 Molecular Weight 372.68
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 37.27, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 9.32, Max Conc. mM: 25
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
