| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab191796-10μg (Trial Size) Apply for free trial size（?） Every year, as a valued customer, you have the exclusive opportunity to explore and enjoy three different trial products of your choice, absolutely free! | 10μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 | |
| Ab191796-25μg | 25μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $129.90 | |
| Ab191796-100μg | 100μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $329.90 |
mAb (P84); Rat anti Mouse SIRP alpha/CD172a Antibody (AF700); Flow
| Product Name | SIRP alpha/CD172a Rat mAb (AF700) |
|---|---|
| Synonyms | Bit | SIRP | SHP-1 | Ptpns1 | Idd13.2 | BITbrain-immunoglobulin-like molecule with tyrosine-based activation motifs | Brain Ig-like molecule with tyrosine-based activation motifs | CD172 antigen-like family member A | CD172a antigen | CD172a | Inhibitory |
| Specifications & Purity | ExactAb™, Validated, Ex:696nm, Em:719nm, 0.5 mg/mL |
| Biochemical and Physiological Mechanisms | Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial |
| Host species | Rat |
| Specificity | SIRP alpha/CD172a |
| Immunogen | Mouse brain membrane protein |
| Positive Control | Flow: C57BL/6 mouse bone marrow cells. |
| Conjugation | Alexa Fluor® 700 |
| Grade | Em:719nm, Ex:696nm, ExactAb™, Validated |
| Product Description | Rat anti Mouse SIRP alpha/CD172a Antibody, Monoclonal (P84), could be used for in vivo SIRPα blocking, in vitro SIRPα blocking, WB, IP, Flow and so on. |
| Isotype | Rat IgG1 |
|---|---|
| Light Chain Type | kappa |
| Purification Method | Protein A purified |
| Concentration | 0.5 mg/mL |
| Storage Temp | Store at 2-8°C,Protected from light,Freeze prohibited |
| Shipped In | Wet ice |
| Stability And Storage | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
SIRP alpha/CD172a Rat mAb (AF700) (Ab191796) - Flow Cytometry
Flow cytometry analysis of SIRP alpha/CD172a expression by C57BL/6 mouse bone marrow cells (right panel) compared to an isotype control (left panel). Cells were stained with SIRP alpha/CD172a Rat mAb (AF700) (Ab191796) at 0.2μg/test for 1 hour at 4°C. Left panel - Rat IgG (AF700) (Ab190242).
SIRP alpha/SIRP alpha/CD172a Rat mAb (AF700) (Ab191796) - Flow Cytometry
Flow cytometry analysis of SIRP alpha/CD172a expression by C57BL/6 mouse bone marrow cells (red) compared to an isotype control (blue). Cells were stained with SIRP alpha/CD172a Rat mAb (AF700) (Ab191796) at 0.2μg/test for 1 hour at 4°C. Blue - Rat IgG (AF700) (Ab190242). Black - Unlabelled control, cells without incubation with primary antibody.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| Flow Cytometry | ≤0.1 μg/test For flow cytometric staining, the suggested use of this reagent is ≤0.1 μg per million cells in 100 µL staining volume. |
Enter Lot Number to search for COA:
