Sirtinol can inhibit the transcriptional silencing activity of yeast Sir2p in vivo and the activity of yeast Sir2p and human sirt2 deacetylase in vitro. It can inhibit the physiological regulators of platelet aggregation (such as thrombin and collagen), r
Storage Temp
Protected from light,Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
Application：
Sirtinol is a cell permeable specific inhibitor of sirtuin NAD-dependant deacetylases
1.Nevoral J et al.. (2019) Epigenetic and non-epigenetic mode of SIRT1 action during oocyte meiosis progression.. J Anim Sci Biotechnol, 10 (67). [PMID:31413827]
2.Adamkova K et al.. (2017) SIRT1-dependent modulation of methylation and acetylation of histone H3 on lysine 9 (H3K9) in the zygotic pronuclei improves porcine embryo development.. J Anim Sci Biotechnol, 8 (83). [PMID:29118980]
Solution Calculators
Molarity Calculator
Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator
Determine the dilution needed to prepare a stock solution.
G2219924