Sisomicin sulfate - 98%, high purity , CAS No.53179-09-2

  • ≥98%
Item Number
S303909
Grouped product items
SKUSizeAvailabilityPrice Qty
S303909-250mg
250mg
In stock
$48.90
S303909-1g
1g
In stock
$127.90

Basic Description

SynonymsSISOMICIN SULFATE [MART.] | O-3-Deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-4)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-6))-2-deoxy-L-streptamine sulfate (2:5) (salt) | UNII-K14444371C | Sisomicin sulfate sal
Specifications & Purity≥98%
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
Product Description

Product Describtion:

Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against gram-positive bacteria

Associated Targets(Human)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol;sulfuric acid
INCHI InChI=1S/2C19H37N5O7.5H2O4S/c2*1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;5*1-5(2,3)4/h2*3,9-18,24-27H,4-7,20-23H2,1-2H3;5*(H2,1,2,3,4)/t2*9-,10+,11-,12+,13-,14-,15+,16-,17-,18-,19+;;;;;/m11...../s1
InChi Key CIKNYWFPGZCHDL-ZHFUJENKSA-N
Canonical SMILES CC1(COC(C(C1NC)O)OC2C(CC(C(C2O)OC3C(CC=C(O3)CN)N)N)N)O.CC1(COC(C(C1NC)O)OC2C(CC(C(C2O)OC3C(CC=C(O3)CN)N)N)N)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O
Isomeric SMILES C[C@@]1(CO[C@@H]([C@@H]([C@H]1NC)O)O[C@H]2[C@@H](C[C@@H]([C@H]([C@@H]2O)O[C@@H]3[C@@H](CC=C(O3)CN)N)N)N)O.C[C@@]1(CO[C@@H]([C@@H]([C@H]1NC)O)O[C@H]2[C@@H](C[C@@H]([C@H]([C@@H]2O)O[C@@H]3[C@@H](CC=C(O3)CN)N)N)N)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O
PubChem CID 439243
Molecular Weight 692.72

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
I2301611Certificate of AnalysisAug 21, 2023 S303909
I2301612Certificate of AnalysisAug 21, 2023 S303909
I2301648Certificate of AnalysisAug 21, 2023 S303909
I2301656Certificate of AnalysisAug 21, 2023 S303909

Chemical and Physical Properties

SolubilitySoluble in water
SensitivityAir Sensitive;Heat Sensitive;Moisture Sensitive
Specific Rotation[α]100° (C=1,H2O)
Boil Point(°C)155 °C
Melt Point(°C)73 °C

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Danger
Hazard Statements

H312:Harmful in contact with skin

H332:Harmful if inhaled

H360:May damage fertility or the unborn child

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P362+P364:Take off contaminated clothing and wash it before reuse.

P203:Obtain, read and follow all safety instructions before use.

P318:if exposed or concerned, get medical advice.

P317:Get emergency medical help.

Merck Index 8550

Related Documents

Citations of This Product

1. Wang Chengke, Tan Rong, Li Jiangyu, Zhang Zexiang.  (2019)  Double Magnetic Separation-assisted Fluorescence Method for Sensitive Detection of Ochratoxin A.  CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,  35  (3): (382-389).  [PMID:] [10.1007/s40242-019-8322-3]
2. Chengke Wang, Dan Chen, Qingqing Wang, Rong Tan.  (2017)  Kanamycin detection based on the catalytic ability enhancement of gold nanoparticles.  BIOSENSORS & BIOELECTRONICS,  91  (262).  [PMID:28013021] [10.1016/j.bios.2016.12.042]

References

1. Wang Chengke, Tan Rong, Li Jiangyu, Zhang Zexiang.  (2019)  Double Magnetic Separation-assisted Fluorescence Method for Sensitive Detection of Ochratoxin A.  CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,  35  (3): (382-389).  [PMID:] [10.1007/s40242-019-8322-3]
2. Chengke Wang, Dan Chen, Qingqing Wang, Rong Tan.  (2017)  Kanamycin detection based on the catalytic ability enhancement of gold nanoparticles.  BIOSENSORS & BIOELECTRONICS,  91  (262).  [PMID:28013021] [10.1016/j.bios.2016.12.042]

Solution Calculators