Sivelestat sodium tetrahydrate - ≥98%, high purity , CAS No.201677-61-4

Item Number

S275861

Grouped product items
SKU	Size	Availability	Price
S275861-5mg	5mg	In stock	$49.90
S275861-10mg	10mg	In stock	$82.90
S275861-25mg	25mg	In stock	$186.90
S275861-50mg	50mg	In stock	$284.90
S275861-100mg	100mg	In stock	$414.90
S275861-250mg	250mg	In stock	$933.90
S275861-1g	1g	In stock	$3,361.90
S275861-5g	5g	In stock	$15,126.90

Neutrophil elastase inhibitor

Basic Description

Synonyms	Sivelestat sodium\|201677-61-4\|Sivelestat sodium tetrahydrate\|sivelestat sodium hydrate\|Elaspol\|ONO-5046.Na\|LY544349 Sodium Hydrate\|Sivelestat (sodium tetrahydrate)\|Sivelestat sodium [USAN]\|EI-546\|Ono 5046\|Sivelestat sodium (USAN)\|DTXSID0046727\|Sivelestat
Specifications & Purity	≥98%
Source	Synthetic
Storage Temp	Store at -20°C
Shipped In	Dry ice
Product Description	Store at Room Temperature. The product can be stored for up to 12 months.

Names and Identifiers

IUPAC Name	sodium;2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetate;tetrahydrate
INCHI	InChI=1S/C20H22N2O7S.Na.4H2O/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24;;;;;/h4-11,22H,12H2,1-3H3,(H,21,25)(H,23,24);;4*1H2/q;+1;;;;/p-1
InChi Key	PLHREJBSQUSUCW-UHFFFAOYSA-M
Canonical SMILES	CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].O.O.O.O.[Na+]
Isomeric SMILES	CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].O.O.O.O.[Na+]
PubChem CID	23663985
Molecular Weight	528.51

Certificates

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8 results found

Lot Number	Certificate Type	Date	Item
B2225300	Certificate of Analysis	Sep 20, 2023	S275861
B2225306	Certificate of Analysis	Sep 20, 2023	S275861
B2225815	Certificate of Analysis	Sep 20, 2023	S275861
B2225825	Certificate of Analysis	Sep 20, 2023	S275861
B2225826	Certificate of Analysis	Sep 20, 2023	S275861
B2225829	Certificate of Analysis	Sep 20, 2023	S275861
B2225831	Certificate of Analysis	Sep 20, 2023	S275861
B2225843	Certificate of Analysis	Sep 20, 2023	S275861

References

1. Liu H et al.. (2019) Neutrophil elastase contributes to the pathological vascular permeability characteristic of diabetic retinopathy.. Diabetologia, 62 (12): (2365-2374). [PMID:31612267]
2. Xia X et al.. (2022) Neutrophil extracellular traps promote metastasis in gastric cancer patients with postoperative abdominal infectious complications.. Nat Commun, 13 (1017). [PMID:35197446]
3. Zhang H et al.. (2021) Tissue Factor-Enriched Neutrophil Extracellular Traps Promote Immunothrombosis and Disease Progression in Sepsis-Induced Lung Injury.. Front Cell Infect Microbiol, 11 (677902). [PMID:34336711]

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Basic Description