Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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S275802-5mg | 5mg | In stock | $71.90 | |
S275802-10mg | 10mg | In stock | $109.90 |
Potent, selective D 1 receptor antagonist
Synonyms | MLS000758232 | DTXSID6042606 | AMY38997 | CCG-100754 | CPD000449276 | MLS001423981 | 8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol hydrobromide | Q418109 | AS-73704 | SKF83566 hydrobromide | 8-bromo-3-methyl-5-phenyl-2,3,4,5-tetrahyd |
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Specifications & Purity | ≥95% |
Biochemical and Physiological Mechanisms | Potent, selective D 1 receptor antagonist (K i = 0.4 nM). Centrally active following systemic administration. Various neurological effects in vitro and in vivo . |
Storage Temp | Room temperature,Desiccated |
Shipped In | Normal |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 488200353 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488200353 |
IUPAC Name | 8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol;hydrobromide |
INCHI | InChI=1S/C17H18BrNO.BrH/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12;/h2-6,9-10,15,20H,7-8,11H2,1H3;1H |
InChi Key | SDQJYYGODYRPBR-UHFFFAOYSA-N |
Canonical SMILES | CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)Br.Br |
Isomeric SMILES | CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)Br.Br |
PubChem CID | 23581817 |
Molecular Weight | 413.15 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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D2308488 | Certificate of Analysis | Jan 16, 2024 | S275802 |
D2307893 | Certificate of Analysis | Jan 16, 2024 | S275802 |
D2307877 | Certificate of Analysis | Jan 11, 2024 | S275802 |
D2308484 | Certificate of Analysis | Jan 11, 2024 | S275802 |
L2212242 | Certificate of Analysis | Sep 21, 2023 | S275802 |
L2212241 | Certificate of Analysis | Sep 21, 2023 | S275802 |
Solubility | Soluble in water to 5 mM, in ethanol to 25 mM and in DMSO to 100 mM |
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Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |