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SL-176 , CAS No.S613616, Inhibitor of protein phosphatase; Mg2+/Mn2+ dependent 1D
Basic Description
Synonyms | SL176 |
Specifications & Purity | Moligand™ |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of protein phosphatase; Mg2+/Mn2+ dependent 1D |
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Associated Targets(Human)
Names and Identifiers
IUPAC Name | (1R,3S,4aS,5R,8aR)-3-[tert-butyl(dimethyl)silyl]oxy-1-methyl-5-triethylsilyloxy-3,4,4a,5,6,7,8,8a-octahydro-2H-naphthalene-1-carboxylic acid |
INCHI | InChI=1S/C24H48O4Si2/c1-10-30(11-2,12-3)28-21-15-13-14-20-19(21)16-18(17-24(20,7)22(25)26)27-29(8,9)23(4,5)6/h18-21H,10-17H2,1-9H3,(H,25,26)/t18-,19-,20+,21+,24+/m0/s1 |
InChi Key | WYYKYBVYKSTHEV-RSBOXOOMSA-N |
Canonical SMILES | CC[Si](O[C@@H]1CCC[C@@H]2[C@@H]1C[C@@H](C[C@@]2(C)C(=O)O)O[Si](C(C)(C)C)(C)C)(CC)CC |
Isomeric SMILES | CC[Si](CC)(CC)O[C@@H]1CCC[C@@H]2[C@@H]1C[C@@H](C[C@@]2(C)C(=O)O)O[Si](C)(C)C(C)(C)C |
PubChem CID | 122189279 |
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References
1. Ogasawara S, Kiyota Y, Chuman Y, Kowata A, Yoshimura F, Tanino K, Kamada R, Sakaguchi K. (2015) Novel inhibitors targeting PPM1D phosphatase potently suppress cancer cell proliferation.. Bioorg Med Chem, 23 (19): (6246-9). [PMID:26358280] |
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