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SL-176 , CAS No.S613616, Inhibitor of protein phosphatase; Mg2+/Mn2+ dependent 1D

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SL-176 , CAS No.S613616, Inhibitor of protein phosphatase; Mg2+/Mn2+ dependent 1D

Moligand™

PubChem CID: 122189279

Item Number

S613616

Grouped product items
SKU	Size	Availability	Price	Qty
S613616-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$570.90
S613616-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

protein phosphatase，Mg2+/Mn2+ dependent 1D Inhibitor

Basic Description

Synonyms	SL176
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of protein phosphatase; Mg2+/Mn2+ dependent 1D

Associated Targets(Human)

PPM1D Tchem Protein phosphatase 1D (2 Activities)

Discover Target: PPM1D

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PPM1A Tchem Protein phosphatase 2C alpha (38 Activities)

Discover Target: PPM1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MCF7 (126967 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NCI-H1299 (3248 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(1R,3S,4aS,5R,8aR)-3-[tert-butyl(dimethyl)silyl]oxy-1-methyl-5-triethylsilyloxy-3,4,4a,5,6,7,8,8a-octahydro-2H-naphthalene-1-carboxylic acid
INCHI	InChI=1S/C24H48O4Si2/c1-10-30(11-2,12-3)28-21-15-13-14-20-19(21)16-18(17-24(20,7)22(25)26)27-29(8,9)23(4,5)6/h18-21H,10-17H2,1-9H3,(H,25,26)/t18-,19-,20+,21+,24+/m0/s1
InChi Key	WYYKYBVYKSTHEV-RSBOXOOMSA-N
Canonical SMILES	CC[Si](O[C@@H]1CCC[C@@H]2[C@@H]1C[C@@H](C[C@@]2(C)C(=O)O)O[Si](C(C)(C)C)(C)C)(CC)CC
Isomeric SMILES	CC[Si](CC)(CC)O[C@@H]1CCC[C@@H]2[C@@H]1C[C@@H](C[C@@]2(C)C(=O)O)O[Si](C)(C)C(C)(C)C
PubChem CID	122189279

Database links

PubChem CID	122189279

Certificates

Certificate of Analysis(COA)

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References

1. Ogasawara S, Kiyota Y, Chuman Y, Kowata A, Yoshimura F, Tanino K, Kamada R, Sakaguchi K. (2015) Novel inhibitors targeting PPM1D phosphatase potently suppress cancer cell proliferation.. Bioorg Med Chem, 23 (19): (6246-9). [PMID:26358280] [10.1021/op500134e]

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