SMI-16a - 10mM in DMSO, high purity , CAS No.587852-28-6

  • 10mM in DMSO
Item Number
S424917
Grouped product items
SKUSizeAvailabilityPrice Qty
S424917-1ml
1ml
Available within 8-12 weeks(?)
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$69.90

Pim1 Selective Inhibitors

Basic Description

Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsSMI-16a is a selective Pim kinase inhibitor with IC50 values of 150 nM and 20 nM for Pim1 and Pim2 respectively.
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

Information

SMI-16a is a selectivePimkinase inhibitor with IC50 values of 150 nM and 20 nM for Pim1 and Pim2 respectively.

Targets

Pim2 ; Pim1 20 nM; 150 nM

Product Properties

ALogP2.798
HBD Count1
Rotatable Bond4

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (5E)-5-[(4-propoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione
INCHI InChI=1S/C13H13NO3S/c1-2-7-17-10-5-3-9(4-6-10)8-11-12(15)14-13(16)18-11/h3-6,8H,2,7H2,1H3,(H,14,15,16)/b11-8+
InChi Key GBWOSXZUTXXXQF-DHZHZOJOSA-N
Canonical SMILES CCCOC1=CC=C(C=C1)C=C2C(=O)NC(=O)S2
Isomeric SMILES CCCOC1=CC=C(C=C1)/C=C/2\C(=O)NC(=O)S2
PubChem CID 25102785
Molecular Weight 263.31

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

DMSO(mg / mL) Max Solubility53
DMSO(mM) Max Solubility201.28365804565
Water(mg / mL) Max Solubility<1

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