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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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S424917-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 |
Pim1 Selective Inhibitors
Specifications & Purity | 10mM in DMSO |
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Biochemical and Physiological Mechanisms | SMI-16a is a selective Pim kinase inhibitor with IC50 values of 150 nM and 20 nM for Pim1 and Pim2 respectively. |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Product Description | Information SMI-16a is a selectivePimkinase inhibitor with IC50 values of 150 nM and 20 nM for Pim1 and Pim2 respectively. Targets Pim2 ; Pim1 20 nM; 150 nM |
ALogP | 2.798 |
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HBD Count | 1 |
Rotatable Bond | 4 |
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (5E)-5-[(4-propoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione |
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INCHI | InChI=1S/C13H13NO3S/c1-2-7-17-10-5-3-9(4-6-10)8-11-12(15)14-13(16)18-11/h3-6,8H,2,7H2,1H3,(H,14,15,16)/b11-8+ |
InChi Key | GBWOSXZUTXXXQF-DHZHZOJOSA-N |
Canonical SMILES | CCCOC1=CC=C(C=C1)C=C2C(=O)NC(=O)S2 |
Isomeric SMILES | CCCOC1=CC=C(C=C1)/C=C/2\C(=O)NC(=O)S2 |
PubChem CID | 25102785 |
Molecular Weight | 263.31 |
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DMSO(mg / mL) Max Solubility | 53 |
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DMSO(mM) Max Solubility | 201.28365804565 |
Water(mg / mL) Max Solubility | <1 |