pAb; Rabbit anti Human SOCS1 Antibody; WB, IHC; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab128582-10μl | 10μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $66.90 | |
| Ab128582-50μl | 50μl | In stock | $189.90 | |
| Ab128582-100μl | 100μl | In stock | $299.90 | |
| Ab128582-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,799.90 |
pAb; Rabbit anti Human SOCS1 Antibody; WB, IHC; Unconjugated
| Product Name | SOCS1 Antibody - Primary antibody, specific to SOCS1, Rabbit IgG |
|---|---|
| Synonyms | CIS1 antibody; CISH 1 antibody; CISH1 antibody; Cytokine inducible SH2 protein 1 antibody; JAB antibody; JAK binding protein antibody; JAK-binding protein antibody; Janus kinase binding protein antibody; SOCS 1 antibody; SOCS-1 antibody; Socs1 antibody; S |
| Specifications & Purity | ExactAb™, Validated, Carrier Free, 0.7 mg/mL |
| Host species | Rabbit |
| Specificity | SOCS1 |
| Immunogen | A synthetic peptide derived from human SOCS1 (AA 149-211). |
| Positive Control | WB: K562, Hep G2, NIH/3T3 and C6 cell lysates. IHC: Human gastric cancer tissues. |
| Conjugation | Unconjugated |
| Grade | Carrier Free, ExactAb™, Validated |
| Product Description | Rabbit anti Human SOCS1 Antibody, Polyclonal antibody, could be used for WB, IHC and so on. |
| Isotype | Rabbit IgG |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
SOCS1 Antibody (Ab128582) - Western Blot
All lanes: SOCS1 Antibody (Ab128582) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 24 kDa
Observed band size: 23 kDa
Exposure time: 10.2 s
SOCS1 Antibody (Ab128582) - IHC
Immunohistochemistry analysis of paraffin-embedded Human gastric cancer using SOCS1 Antibody (Ab128582). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50 - 1/100 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0505986 | Certificate of Analysis | May 23, 2024 | Ab128582 |
| ZJ24F0505985 | Certificate of Analysis | May 23, 2024 | Ab128582 |
| ZJ24F0505984 | Certificate of Analysis | May 23, 2024 | Ab128582 |
| ZJ23F1202197 | Certificate of Analysis | Dec 26, 2023 | Ab128582 |
| ZJ23F1202206 | Certificate of Analysis | Dec 26, 2023 | Ab128582 |
| ZJ23F1202043 | Certificate of Analysis | Dec 14, 2023 | Ab128582 |
| ZJ23F1202044 | Certificate of Analysis | Dec 14, 2023 | Ab128582 |
| 1. Starr, R R and 10 more authors.. (1997) A family of cytokine-inducible inhibitors of signalling.. Nature, (26): [PMID:9202125] |
| 2. Endo, T A TA and 16 more authors.. (1997) A new protein containing an SH2 domain that inhibits JAK kinases.. Nature, (26): [PMID:9202126] |
| 3. Minamoto, S S and 9 more authors.. (1997) Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3.. Biochemical and biophysical research communications, (8): [PMID:9266833] |
| 4. Ohya, K i Ki and 9 more authors.. (1997) SOCS-1/JAB/SSI-1 can bind to and suppress Tec protein-tyrosine kinase.. The Journal of biological chemistry, (24): [PMID:9341160] |
| 5. Dey, B R BR, Spence, S L SL, Nissley, P P and Furlanetto, R W RW.. (1998) Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor.. The Journal of biological chemistry, (11): [PMID:9727029] |
| 6. Yandava, C N CN, Pillari, A A and Drazen, J M JM.. (1999) Radiation hybrid and cytogenetic mapping of SOCS1 and SOCS2 to chromosomes 16p13 and 12q, respectively.. Genomics, (1): [PMID:10512686] |
| 7. Kamizono, S S and 13 more authors.. (2001) The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2.. The Journal of biological chemistry, (20): [PMID:11278610] |
| 8. Frantsve, J J, Schwaller, J J, Sternberg, D W DW, Kutok, J J and Gilliland, D G DG.. (2001) Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation.. Molecular and cellular biology, [PMID:11313480] |
| 9. Krebs, D L DL and Hilton, D J DJ.. (2001) SOCS proteins: negative regulators of cytokine signaling.. Stem cells (Dayton, Ohio), [PMID:11553846] |
| 10. Wang, Jianping J and Campbell, Iain L IL.. (2002) Cytokine signaling in the brain: putting a SOCS in it?. Journal of neuroscience research, (15): [PMID:11835308] |
| 11. Toniato, Elena E and 5 more authors.. (2002) TRIM8/GERP RING finger protein interacts with SOCS-1.. The Journal of biological chemistry, (4): [PMID:12163497] |
| 12. Hafizi, Sassan S, Alindri, Filiz F, Karlsson, Roger R and Dahlbäck, Björn B.. (2002) Interaction of Axl receptor tyrosine kinase with C1-TEN, a novel C1 domain-containing protein with homology to tensin.. Biochemical and biophysical research communications, (20): [PMID:12470648] |
| 13. Ben-Zvi, Tal T, Yayon, Avner A, Gertler, Arieh A and Monsonego-Ornan, Efrat E.. (2006) Suppressors of cytokine signaling (SOCS) 1 and SOCS3 interact with and modulate fibroblast growth factor receptor signaling.. Journal of cell science, (15): [PMID:16410555] |
| 14. Heir, Pardeep P and 5 more authors.. (2013) DCNL1 functions as a substrate sensor and activator of cullin 2-RING ligase.. Molecular and cellular biology, [PMID:23401859] |
| 15. Thaventhiran, James E D and 59 more authors.. (2020) Whole-genome sequencing of a sporadic primary immunodeficiency cohort.. Nature, [PMID:32499645] |
| 16. Lee, Pui Y and 11 more authors.. (2020) Immune dysregulation and multisystem inflammatory syndrome in children (MIS-C) in individuals with haploinsufficiency of SOCS1.. The Journal of allergy and clinical immunology, [PMID:32853638] |
| 17. Hadjadj, Jérôme and 42 more authors.. (2020) Early-onset autoimmunity associated with SOCS1 haploinsufficiency.. Nature communications, (21): [PMID:33087723] |
