Grouped product items

SKU

Size

Availability

Price

Qty

X131756-5g

Available within 4-8 weeks(?)

$20.90

X131756-25g

25g

Available within 4-8 weeks(?)

$77.90

X131756-100g

100g

Available within 4-8 weeks(?)

$280.90

X131756-500g

500g

Available within 4-8 weeks(?)

$1,261.90

Basic Description

Synonyms	150-83-4 \| Sodium 3-hydroxybutyrate \| sodium 3-hydroxybutanoate \| DL-3-Hydroxybutyric Acid Sodium Salt \| 306-31-0 \| sodium;3-hydroxybutanoate \| sodium beta-Hydroxybutyrate \| DL-3-Hydroxybutyric acid, sodium salt \| Sodium R-3-Hydroxybutyrate-d4 \| 3-Hydroxybutyric acid (sodi
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	β-Hydroxybutyric acid is a ketone body present in the rumen epithelium of liver cells. Its interconversion to acetoacetate influences the acid-base balance and is coupled NADH generation from (nicotinamide adenine dinucleotide) NAD+, measured fluorimetric
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice
Note	1g/5g卖完停产，不再备货

Associated Targets(Human)

HEK293 (82097 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FFAR3 Tchem Free fatty acid receptor 3 (304 Activities)

Discover Target: FFAR3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC26A4 Tbio Pendrin (86 Activities)

Discover Target: SLC26A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	sodium;3-hydroxybutanoate
INCHI	InChI=1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1
InChi Key	NBPUSGBJDWCHKC-UHFFFAOYSA-M
Canonical SMILES	CC(CC(=O)[O-])O.[Na+]
Isomeric SMILES	CC(CC(=O)[O-])O.[Na+]
WGK Germany	3
Alternate CAS	306-31-0
PubChem CID	23676771
Molecular Weight	126.09
Beilstein	4824866

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

9 results found

Lot Number	Certificate Type	Date	Item
H2401277	Certificate of Analysis	Jun 28, 2024	X131756
H2401278	Certificate of Analysis	Jun 28, 2024	X131756
H2401279	Certificate of Analysis	Jun 28, 2024	X131756
E2317786	Certificate of Analysis	Jan 31, 2023	X131756
E2317807	Certificate of Analysis	Jan 31, 2023	X131756
C2226471	Certificate of Analysis	Mar 08, 2022	X131756
C2226472	Certificate of Analysis	Mar 08, 2022	X131756
C2226503	Certificate of Analysis	Mar 08, 2022	X131756
C2226504	Certificate of Analysis	Mar 08, 2022	X131756

Chemical and Physical Properties

Sensitivity	Moisture sensitive
Melt Point(°C)	167-170°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3

References

1. Tyzio R et al.. (2011) Depolarizing actions of GABA in immature neurons depend neither on ketone bodies nor on pyruvate.. J Neurosci, 31 (34-45). [PMID:21209187]
2. Gebert N et al.. (2020) Region-Specific Proteome Changes of the Intestinal Epithelium during Aging and Dietary Restriction.. Cell Rep, 31 (4): (107565). [PMID:32348758]
3. Huating Li,Zhanguo Gao,Jin Zhang,Xin Ye,Aimin Xu,Jianping Ye,Weiping Jia. (2012-02-18) Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3.. Diabetes, 61 ((4)): (797-806). [PMID:22338096]
4. Nikolaj Rittig,Henrik H Thomsen,Ermina Bach,Jens Otto L Jørgensen,Niels Møller. (2015-04-22) Hormone and Cytokine Responses to Repeated Endotoxin Exposures-No Evidence of Endotoxin Tolerance After 5 Weeks in Humans.. Shock (Augusta, Ga.), 44 ((1)): (32-35). [PMID:25895146]
5. Sabrina Chriett,Arkadiusz Dąbek,Martyna Wojtala,Hubert Vidal,Aneta Balcerczyk,Luciano Pirola. (2019-01-27) Prominent action of butyrate over β-hydroxybutyrate as histone deacetylase inhibitor, transcriptional modulator and anti-inflammatory molecule.. Scientific reports, 9 ((1)): (742-742). [PMID:30679586]
6. Catalina Pineda Molina,George S Hussey,Jonas Eriksson,Michael A Shulock,Laura L Cárdenas Bonilla,Ross M Giglio,Riddhi M Gandhi,Brian M Sicari,Derek Wang,Ricardo Londono,Denver M Faulk,Neill J Turner,Stephen F Badylak. (2019-04-16) 4-Hydroxybutyrate Promotes Endogenous Antimicrobial Peptide Expression in Macrophages.. Tissue engineering. Part A, 25 ((9-10)): (693-706). [PMID:30982430]
7. Chia-Wei Cheng,Moshe Biton,Adam L Haber,Nuray Gunduz,George Eng,Liam T Gaynor,Surya Tripathi,Gizem Calibasi-Kocal,Steffen Rickelt,Vincent L Butty,Marta Moreno-Serrano,Ameena M Iqbal,Khristian E Bauer-Rowe,Shinya Imada,Mehmet Sefa Ulutas,Constantine Mylonas,Mark T Whary,Stuart S Levine,Yasemin Basbinar,Richard O Hynes,Mari Mino-Kenudson,Vikram Deshpande,Laurie A Boyer,James G Fox,Christopher Terranova,Kunal Rai,Helen Piwnica-Worms,Maria M Mihaylova,Aviv Regev,Ömer H Yilmaz. (2019-08-24) Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet.. Cell, 178 ((5)): (1115-1131). [PMID:31442404]
8. Stephanie Lilja,Julia Oldenburg,Angelika Pointner,Laura Dewald,Mariam Lerch,Berit Hippe,Olivier Switzeny,Alexander Haslberger. (2020-11-06) Epigallocatechin Gallate Effectively Affects Senescence and Anti-SASP via SIRT3 in 3T3-L1 Preadipocytes in Comparison with Other Bioactive Substances.. Oxidative medicine and cellular longevity, 2020 (4793125-4793125). [PMID:33149809]
9. Anna Go, Sung Ryul Park, Yejin Ku, Mingge Sun, Sangho Yeon, Jin-Kyun Lee, Sang Wook Lee, Min-Ho Lee,. (2021-07-25) Highly Sensitive Electrochemical Sensor for Diagnosis of Diabetic Ketoacidosis (DKA) by Measuring Ketone Bodies in Urine.. Sensors (Basel, Switzerland), 21 ((14) ): [PMID:34300644]
10. Brian A Parker,Chase M Walton,Sheryl T Carr,Jacob L Andrus,Eric C K Cheung,Michael J Duplisea,Esther K Wilson,Carrie Draney,Daniel R Lathen,Kyle B Kenner,David M Thomson,Jeffery S Tessem,Benjamin T Bikman. (2018-08-04) β-Hydroxybutyrate Elicits Favorable Mitochondrial Changes in Skeletal Muscle.. International journal of molecular sciences, 19 ((8)): [PMID:30071599]
11. Esben Thyssen Vestergaard,Astrid Johanneson Hjelholt,Rune E Kuhre,Niels Møller,Pierre Larraufie,Fiona M Gribble,Frank Reimann,Niels Jessen,Jens Juul Holst,Jens Otto Lunde Jørgensen. (2019-02-07) Acipimox Acutely Increases GLP-1 Concentrations in Overweight Subjects and Hypopituitary Patients.. The Journal of clinical endocrinology and metabolism, 104 ((7)): (2581-2592). [PMID:30726969]
12. Shengying Pan,Peili Hu,Qingsheng You,Jinliang Chen,Jingjing Wu,Yaru Zhang,Zixuan Cai,Ting Ye,Xing Xu,Zhuo Chen,Lijuan Tong,Chao Huang,Haiyan He. (2020-01-03) Evaluation of the antidepressive property of β-hydroxybutyrate in mice.. Behavioural pharmacology, 31 ((4)): (322-332). [PMID:31895061]
13. Carolina Akiko Sato Cabral Araújo,Antonio Humberto Hamad Minervino,Rejane Santos Sousa,Francisco Leonardo Costa Oliveira,Frederico Augusto Mazzocca Lopes Rodrigues,Clara Satsuki Mori,Enrico Lippi Ortolani. (2020-04-21) Validation of a handheld β-hydroxybutyrate acid meter to identify hyperketonaemia in ewes.. PeerJ, 8 (e8933-e8933). [PMID:32309049]
14. Miller, et al.. (2020) A ketogenic diet combined with exercise alters mitochondrial function in human skeletal muscle while improving metabolic health.. American Journal of Physiology. Endocrinology and Metabolism, 319 (E995-E1007). [PMID:32985255]
15. Hossein Ghahremani,Majid Sirati-Sabet,Siamak Salami. (2021-09-02) Evaluation of Impacts of Cellular Metabolism on the Migration of Ovarian Cancer Cells by Two in Vitro Assays: A Method Comparison Study.. Galen medical journal, 9 (e1831-e1831). [PMID:34466600]

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(±)-Sodium 3-hydroxybutyrate - 98%, high purity , CAS No.150-83-4

Basic Description

Associated Targets(Human)

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

SKU	Size	Availability	Price
X131756-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$20.90
X131756-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$77.90
X131756-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$280.90
X131756-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,261.90