Click Here for 5% Off Your First Aladdin Purchase!

Sodium 4-Phenylbutyrate - ≥98%, high purity , Glutamine sequestering agent, CAS No.1716-12-7, Glutamine sequestering agent

  • ≥98%
Item Number
S305161
Grouped product items
SKUSizeAvailabilityPrice Qty
S305161-200mg
200mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$22.90
S305161-1g
1g
In stock
$89.90
S305161-5g
5g
In stock
$307.90
S305161-25g
25g
In stock
$1,385.90
S305161-100g
100g
In stock
$4,986.90

Histone deacetylase inhibitor

View related series
Epigenetics

Basic Description

SynonymsSodium 4-phenylbutyrate|SODIUM PHENYLBUTYRATE|1716-12-7|sodium 4-phenylbutanoate|Buphenyl|Ammonaps|TriButyrate|Benzenebutanoic acid, sodium salt|Pheburane|4PBA|4-phenylbutyric acid, sodium salt|4-phenylbutyric acid sodium|NSC 657802|UNII-NT6K61736T|OLPRUV
Specifications & Purity≥98%
Biochemical and Physiological MechanismsHistone deacetylase (HDAC) inhibitor. Able to induce apoptosis, differentiation and promote the maturation of a variety of malignant cells. Inhibits glioma cell proliferation.
Storage TempRoom temperature,Desiccated
Shipped InNormal
Action TypeSEQUESTERING AGENT
Mechanism of actionGlutamine sequestering agent
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HDAC1 Tclin Histone deacetylase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488179889
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488179889
IUPAC Name sodium;4-phenylbutanoate
INCHI InChI=1S/C10H12O2.Na/c11-10(12)8-4-7-9-5-2-1-3-6-9;/h1-3,5-6H,4,7-8H2,(H,11,12);/q;+1/p-1
InChi Key VPZRWNZGLKXFOE-UHFFFAOYSA-M
Canonical SMILES C1=CC=C(C=C1)CCCC(=O)[O-].[Na+]
Isomeric SMILES C1=CC=C(C=C1)CCCC(=O)[O-].[Na+]
PubChem CID 5258
Molecular Weight 186.18

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

8 results found

Lot NumberCertificate TypeDateItem
G2108350Certificate of AnalysisMay 17, 2024 S305161
G2108352Certificate of AnalysisMay 17, 2024 S305161
E2304376Certificate of AnalysisOct 21, 2022 S305161
K2205291Certificate of AnalysisOct 21, 2022 S305161
K2205292Certificate of AnalysisOct 21, 2022 S305161
K2205293Certificate of AnalysisOct 21, 2022 S305161
K2205294Certificate of AnalysisOct 21, 2022 S305161
E2304368Certificate of AnalysisMay 20, 2021 S305161

Chemical and Physical Properties

SolubilitySoluble in water

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H319:Causes serious eye irritation

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

Related Documents

References

1. Qie X et al..  (2017)  Endoplasmic Reticulum Stress Mediates Methamphetamine-Induced Blood-Brain Barrier Damage..  Front Pharmacol,  (639).  [PMID:28959203]
2. Okhovat MA et al..  (2018)  The effect of histone deacetylase inhibitors on AHSP expression..  PLoS One,  13  (2): (e0189267).  [PMID:29389946]

Solution Calculators