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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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S104128-500g | 500g | In stock | $28.90 |
Synonyms | sodium benzoate|532-32-1|Sobenate|Antimol|Benzoic acid, sodium salt|Benzoic acid sodium salt|Benzoate sodium|Benzoate of soda|Benzoate, sodium|Sodiumbenzoate|sodium;benzoate|Natrium benzoicum|FEMA No. 3025|Fuminaru|Benzoan sodny|Caswell No. 746|Microcare |
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Specifications & Purity | pharmaceutical grade, PharmPure™ |
Shipped In | Normal |
Grade | pharmaceutical grade, PharmPure™ |
Product Description | Sodium benzoate is a reagent used in the synthesis of benzene-based derivatives, specifically 5-pyrazolinone derivatives, and aminoflavones and trihydroxybenzoyl flavanoid analogs. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | sodium;benzoate |
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INCHI | InChI=1S/C7H6O2.Na/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H,8,9);/q;+1/p-1 |
InChi Key | WXMKPNITSTVMEF-UHFFFAOYSA-M |
Canonical SMILES | C1=CC=C(C=C1)C(=O)[O-].[Na+] |
Isomeric SMILES | C1=CC=C(C=C1)C(=O)[O-].[Na+] |
WGK Germany | 1 |
RTECS | DH6650000 |
PubChem CID | 517055 |
Molecular Weight | 144.1 |
Beilstein | 3572467 |
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Solubility | Soluble in water and alcohol. |
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Sensitivity | Moisture sensitive. |
Flash Point(°C) | >100°C |
Melt Point(°C) | 300°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H319:Causes serious eye irritation |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P264:Wash hands [and …] thoroughly after handling. P337+P313:IF eye irritation persists: Get medical advice/attention. |
WGK Germany | 1 |
RTECS | DH6650000 |
Merck Index | 8582 |
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2. B Nair. (2002-01-05) Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate.. International journal of toxicology, 20 Suppl 3 (23-50). [PMID:11766131] |
3. Alessio Innocenti,Daniela Vullo,Andrea Scozzafava,Joseph R Casey,Claudiut Supuran. (2005-01-25) Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with carboxylates.. Bioorganic & medicinal chemistry letters, 15 ((3)): (573-578). [PMID:15664815] |
4. Saurav Brahmachari,Kalipada Pahan. (2007-06-21) Sodium benzoate, a food additive and a metabolite of cinnamon, modifies T cells at multiple steps and inhibits adoptive transfer of experimental allergic encephalomyelitis.. Journal of immunology (Baltimore, Md. : 1950), 179 ((1)): (275-283). [PMID:17579047] |
5. Huey-Jen Tsay,Yun-Hsin Wang,Wei-Li Chen,Mei-Yun Huang,Yau-Hung Chen. (2007-07-24) Treatment with sodium benzoate leads to malformation of zebrafish larvae.. Neurotoxicology and teratology, 29 ((5)): (562-569). [PMID:17644306] |
6. J L Poo,E Cervera,A de Hoyos,S Gil,M Cadena,M Uribe. (1990-07-01) [Rationale for the use of sodium benzoate in clinical hepatology].. Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion, 42 Suppl (101-105). [PMID:19256146] |
7. Alessio Innocenti,Rebecca A Hall,Christine Schlicker,Fritz A Mühlschlegel,Claudiu T Supuran. (2009-03-20) Carbonic anhydrase inhibitors. Inhibition of the beta-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with aliphatic and aromatic carboxylates.. Bioorganic & medicinal chemistry, 17 ((7)): (2654-2657). [PMID:19297172] |
8. Denis Fourches,Julie C Barnes,Nicola C Day,Paul Bradley,Jane Z Reed,Alexander Tropsha. (2009-12-18) Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.. Chemical research in toxicology, 23 ((1)): (171-183). [PMID:20014752] |
9. Fabrizio Carta,Alessio Innocenti,Rebecca A Hall,Fritz A Mühlschlegel,Andrea Scozzafava,Claudiu T Supuran. (2011-03-16) Carbonic anhydrase inhibitors. Inhibition of the β-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with branched aliphatic/aromatic carboxylates and their derivatives.. Bioorganic & medicinal chemistry letters, 21 ((8)): (2521-2526). [PMID:21402476] |
10. Yumei Dai,Lynne A McLandsborough,Jochen Weiss,Micha Peleg. (2011-05-04) Concentration and application order effects of sodium benzoate and eugenol mixtures on the growth inhibition of Saccharomyces cerevisiae and Zygosaccharomyces bailii.. Journal of food science, 75 ((7)): (M482-M488). [PMID:21535560] |
11. Jia Li,Xiang Liu,Yan Liu,Juliana Ramsay,Chenchao Yao,Ruihua Dai. (2011-05-18) The effect of continuous exposure of copper on the properties and extracellular polymeric substances (EPS) of bulking activated sludge.. Environmental science and pollution research international, 18 ((9)): (1567-1573). [PMID:21584640] |
12. Matthew J Palframan,Gabriele Kociok-Köhn,Simon E Lewis. (2011-05-20) Total synthesis of (+)-grandifloracin by iron complexation of a microbial arene oxidation product.. Organic letters, 13 ((12)): (3150-3153). [PMID:21591657] |
13. Saurabh Khasnavis,Kalipada Pahan. (2011-06-28) Sodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective Parkinson disease protein DJ-1 in astrocytes and neurons.. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 7 ((2)): (424-435). [PMID:21701815] |
14. Christian Ciardi,Marcel Jenny,Alexander Tschoner,Florian Ueberall,Josef Patsch,Michael Pedrini,Christoph Ebenbichler,Dietmar Fuchs. (2011-08-02) Food additives such as sodium sulphite, sodium benzoate and curcumin inhibit leptin release in lipopolysaccharide-treated murine adipocytes in vitro.. The British journal of nutrition, 107 ((6)): (826-833). [PMID:21801469] |
15. Marouani Imen,Benrhouma Hanene,Kraoua Ichraf,Rouissi Aida,Turki Ilhem,Kaabachi Naziha,Gouider-Khouja Neziha. (2011-08-02) Methylmalonic acidemia and hyperglycemia: an unusual association.. Brain & development, 34 ((2)): (113-114). [PMID:21802231] |
16. Yue Mu,Jing Lin,Rutao Liu. (2011-09-06) Interaction of sodium benzoate with trypsin by spectroscopic techniques.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 83 ((1)): (130-135). [PMID:21890401] |
17. Ismail Hewala,Hamed El-Fatatry,Ehab Emam,Mokhtar Mabrouk. (2011-12-15) Development and application of a validated stability-indicating high-performance liquid chromatographic method using photodiode array detection for simultaneous determination of granisetron, methylparaben, propylparaben, sodium benzoate, and their main degradation products in oral pharmaceutical preparations.. Journal of AOAC International, 94 ((5)): (1447-1460). [PMID:22165009] |
18. Sandesh C S Nagamani,Ayelet Erez,Brendan Lee. (2012-01-14) Argininosuccinate lyase deficiency.. Genetics in medicine : official journal of the American College of Medical Genetics, 14 ((5)): (501-507). [PMID:22241104] |
19. Xu Huang,Hui Kong,Mi Tang,Ming Lu,Jian-Hua Ding,Gang Hu. (2012-01-28) D-Serine regulates proliferation and neuronal differentiation of neural stem cells from postnatal mouse forebrain.. CNS neuroscience & therapeutics, 18 ((1)): (4-13). [PMID:22280157] |
20. Bibhuti B Mishra,Satyendra Gautam,Arun Sharma. (2012-03-16) Shelf life extension of sugarcane juice using preservatives and gamma radiation processing.. Journal of food science, 76 ((8)): (M573-M578). [PMID:22417599] |
21. Bonnie L Beezhold,Carol S Johnston,Kathleen A Nochta. (2012-04-28) Sodium benzoate-rich beverage consumption is associated with increased reporting of ADHD symptoms in college students: a pilot investigation.. Journal of attention disorders, 18 ((3)): (236-241). [PMID:22538314] |
22. Teja Gaonkar,Pramoda Kumar Nayak,Sandeep Garg,Saroj Bhosle. (2012-05-26) Siderophore-producing bacteria from a sand dune ecosystem and the effect of sodium benzoate on siderophore production by a potential isolate.. TheScientificWorldJournal, 2012 (857249-857249). [PMID:22629215] |
23. Jung Min Ko,Choong Ho Shin,Sei Won Yang,Moon Woo Seong,Sung Sup Park,Junghan Song. (2012-08-10) The first Korean case of lysinuric protein intolerance: presented with short stature and increased somnolence.. Journal of Korean medical science, 27 ((8)): (961-964). [PMID:22876067] |
24. Trelita de Sousa,Saroj Bhosle. (2012-09-04) Isolation and characterization of a lipopeptide bioemulsifier produced by Pseudomonas nitroreducens TSB.MJ10 isolated from a mangrove ecosystem.. Bioresource technology, 123 (256-262). [PMID:22940327] |
25. Charline Corre,Catherine Couriol,Abdeltif Amrane,Eric Dumont,Yves Andrès,Pierre Le Cloirec. (2012-09-20) Efficiency of biological activator formulated material (BAFM) for volatile organic compounds removal--preliminary batch culture tests with activated sludge.. Environmental technology, 33 ((13-15)): (1671-1676). [PMID:22988627] |
26. Ariadni C Loutsidou,Vasiliki I Hatzi,C T Chasapis,Georgia I Terzoudi,Chara A Spiliopoulou,Maria E Stefanidou. (2012-11-09) DNA content alterations in Tetrahymena pyriformis macronucleus after exposure to food preservatives sodium nitrate and sodium benzoate.. Acta biologica Hungarica, 63 ((4)): (483-489). [PMID:23134605] |
27. Nilesh Jain,Ruchi Jain,Deepak Kumar Jain,Rajesh Kumar Maheshwari,Surendra Jain. (2012-12-25) Novel UV-spectrophotometric method for quantitative estimation of furazolidone using mixed hydrotropic agent.. Pakistan journal of pharmaceutical sciences, 26 ((1)): (159-162). [PMID:23261742] |
28. Chien-Han Lai. (2013-03-15) Sodium benzoate, a D-amino acid oxidase inhibitor, increased volumes of thalamus, amygdala, and brainstem in a drug-naïve patient with major depression.. The Journal of neuropsychiatry and clinical neurosciences, 25 ((1)): (E50-E51). [PMID:23487233] |
29. Guowen Zhang,Yadi Ma. (2013-06-19) Spectroscopic studies on the interaction of sodium benzoate, a food preservative, with calf thymus DNA.. Food chemistry, 141 ((1)): (41-47). [PMID:23768324] |
30. Hsien-Yuan Lane,Ching-Hua Lin,Michael F Green,Gerhard Hellemann,Chih-Chia Huang,Po-Wei Chen,Rene Tun,Yue-Cung Chang,Guochuan E Tsai. (2013-10-04) Add-on treatment of benzoate for schizophrenia: a randomized, double-blind, placebo-controlled trial of D-amino acid oxidase inhibitor.. JAMA psychiatry, 70 ((12)): (1267-1275). [PMID:24089054] |
31. Mingqi Xie,Haifeng Ye,Ghislaine Charpin-El Hamri,Martin Fussenegger. (2014-07-18) Antagonistic control of a dual-input mammalian gene switch by food additives.. Nucleic acids research, 42 ((14)): (e116-e116). [PMID:25030908] |
32. Aditya M Kunjapur,Yekaterina Tarasova,Kristala L J Prather. (2014-07-31) Synthesis and accumulation of aromatic aldehydes in an engineered strain of Escherichia coli.. Journal of the American Chemical Society, 136 ((33)): (11644-11654). [PMID:25076127] |
33. Sonal Dalvi,Carla Nicholson,Fares Najar,Bruce A Roe,Patricia Canaan,Steven D Hartson,Babu Z Fathepure. (2014-08-26) Arhodomonas sp. strain Seminole and its genetic potential to degrade aromatic compounds under high-salinity conditions.. Applied and environmental microbiology, 80 ((21)): (6664-6676). [PMID:25149520] |
34. Stephen T Vito,Adam T Austin,Christopher N Banks,Bora Inceoglu,Donald A Bruun,Dorota Zolkowska,Daniel J Tancredi,Michael A Rogawski,Bruce D Hammock,Pamela J Lein. (2014-12-03) Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops seizures and modulates neuroinflammation in a murine model of acute TETS intoxication.. Toxicology and applied pharmacology, 281 ((2)): (185-194). [PMID:25448683] |
35. Belinda S Lennerz,Scott B Vafai,Nigel F Delaney,Clary B Clish,Amy A Deik,Kerry A Pierce,David S Ludwig,Vamsi K Mootha. (2014-12-17) Effects of sodium benzoate, a widely used food preservative, on glucose homeostasis and metabolic profiles in humans.. Molecular genetics and metabolism, 114 ((1)): (73-79). [PMID:25497115] |
36. Susanta Mondal,Kalipada Pahan. (2015-01-09) Cinnamon ameliorates experimental allergic encephalomyelitis in mice via regulatory T cells: implications for multiple sclerosis therapy.. PloS one, 10 ((1)): (e0116566-e0116566). [PMID:25569428] |
37. Saroj Kumar Amar,Shruti Goyal,Syed Faiz Mujtaba,Ashish Dwivedi,Hari Narayan Kushwaha,Ankit Verma,Deepti Chopra,Rajnish K Chaturvedi,Ratan Singh Ray. (2015-03-25) Role of type I & type II reactions in DNA damage and activation of caspase 3 via mitochondrial pathway induced by photosensitized benzophenone.. Toxicology letters, 235 ((2)): (84-95). [PMID:25800561] |
38. Ertan Ermis,Christian Hertel,Christin Schneider,Reinhold Carle,Florian Stintzing,Herbert Schmidt. (2015-04-14) Characterization of in vitro antifungal activities of small and American cranberry (Vaccinium oxycoccos L. and V. macrocarpon Aiton) and lingonberry (Vaccinium vitis-idaea L.) concentrates in sugar reduced fruit spreads.. International journal of food microbiology, 204 (111-117). [PMID:25868124] |
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41. Junjie Wang,Guiyun Xu,Wei Wang,Shenghao Xu,Xiliang Luo. (2015-07-18) Nitrite Oxidation with Copper-Cobalt Nanoparticles on Carbon Nanotubes Doped Conducting Polymer PEDOT Composite.. Chemistry, an Asian journal, 10 ((9)): (1892-1897). [PMID:26183223] |
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44. Rui Cai,Yahong Yuan,Zhouli Wang,Chunfeng Guo,Bin Liu,Chunqing Pan,Laping Liu,Tianli Yue. (2015-08-25) Effects of preservatives on Alicyclobacillus acidoterrestris growth and guaiacol production.. International journal of food microbiology, 214 (145-150). [PMID:26301383] |
45. Khushbu K Modi,Malabendu Jana,Susanta Mondal,Kalipada Pahan. (2015-09-25) Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Upregulates Ciliary Neurotrophic Factor in Astrocytes and Oligodendrocytes.. Neurochemical research, 40 ((11)): (2333-2347). [PMID:26399250] |
46. Nicole K Richards-Henderson,Crisand Anderson,Cort Anastasio,Barbara J Finlayson-Pitts. (2015-11-19) The effect of cations on NO2 production from the photolysis of aqueous thin water films of nitrate salts.. Physical chemistry chemical physics : PCCP, 17 ((48)): (32211-32218). [PMID:26577172] |
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49. Chien-Han Lai,Hsien-Yuan Lane,Guochuan Emil Tsai. (2011-12-20) Clinical and cerebral volumetric effects of sodium benzoate, a D-amino acid oxidase inhibitor, in a drug-naïve patient with major depression.. Biological psychiatry, 71 ((4)): (e9-e10). [PMID:22177737] |
50. Dae Eun Choi,Kang Wook Lee,Young Tai Shin,Ki Ryang Na. (2012-05-09) Hyperammonemia in a patient with late-onset ornithine carbamoyltransferase deficiency.. Journal of Korean medical science, 27 ((5)): (556-559). [PMID:22563224] |
51. Tomás Subils,Virginia Aquili,Guillermo Ebner,Claudia Balagué. (2012-05-09) Effect of preservatives on Shiga toxigenic phages and Shiga toxin of Escherichia coli O157:H7.. Journal of food protection, 75 ((5)): (959-965). [PMID:22564948] |
52. Tobias Gräber,Holger Kluge,Frank Hirche,Jirí Broz,Gabriele I Stangl. (2012-06-26) Effects of dietary benzoic acid and sodium-benzoate on performance, nitrogen and mineral balance and hippuric acid excretion of piglets.. Archives of animal nutrition, 66 ((3)): (227-236). [PMID:22724168] |
53. Francesca Mori,Simona Barni,Neri Pucci,Maria Elisabetta Rossi,Maurizio de Martino,Elio Novembre. (2012-08-10) Cutaneous adverse reactions to amoxicillin-clavulanic acid suspension in children: the role of sodium benzoate.. Current drug safety, 7 ((2)): (87-91). [PMID:22873492] |
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58. S Villarruel,L Giannuzzi,S Rivero,A Pinotti. (2015-08-08) Changes induced by UV radiation in the presence of sodium benzoate in films formulated with polyvinyl alcohol and carboxymethyl cellulose.. Materials science & engineering. C, Materials for biological applications, 56 (545-554). [PMID:26249626] |