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Sodium deoxycholate - 98%, high purity , CAS No.302-95-4

10 Citations
  • ≥98%
Item Number
S104198
Grouped product items
SKUSizeAvailabilityPrice Qty
S104198-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$25.90
S104198-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$56.90
S104198-100g
100g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$154.90
S104198-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$599.90
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Water-soluble ionic detergent for the solubilization of membrane-bound proteins.

View related series
Bile alkanes ( bile acids ) [ steroids ] Steroids

Basic Description

SynonymsKybella | sodium (3alpha,5beta,12alpha)-3,12-dihydroxycholan-24-oate | Deoxycholic acid sodium salt | HY-N0593A | Na-Desoxycholat | ISOQUINOLINIUM, 2,2'-(1,5-PENTANEDIYLBIS(OXY(3-OXO-3,1-PROPANEDIYL)))BIS(1-((3,4-DIMETHOXYPHENYL)METHYL)-1,2,3,4-TETRAHYDRO
Specifications & Purity≥98%
Biochemical and Physiological MechanismsSolubilizes fats for absorption in the intestines.Water-soluble ionic detergent useful for extraction of membrane receptors and other plasma membrane proteins. Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to th
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Sodium deoxycholate is an ionic detergent for the solubilization of membrane-bound proteins. Deoxycholic Acid, Sodium Salt is reported to induce tyrosine phosphorylation of b-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 μM). Sodium deoxycholate is a bile salt and an ionic detergent. Bile salts work along with lipids/fats/cholesterol and form mixed micelles in the intestine. These micelles help in fat digestion and absorption through the intestinal wall
An ionic detergent for the solubilization of membrane-bound proteins.

Associated Targets(Human)

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXRA Tclin Retinoid X receptor alpha (3637 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GSTO1 Tchem Glutathione transferase omega 1 (164 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lymphoblastoid cell (5959 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Cruzipain (33337 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name sodium;(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
INCHI InChI=1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1
InChi Key FHHPUSMSKHSNKW-SMOYURAASA-M
Canonical SMILES CC(CCC(=O)[O-])C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C.[Na+]
Isomeric SMILES C[C@H](CCC(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C.[Na+]
WGK Germany 3
RTECS FZ2250000
PubChem CID 23668196
Molecular Weight 414.56
Beilstein 3581950

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

38 results found

Lot NumberCertificate TypeDateItem
H2426391Certificate of AnalysisAug 09, 2024 S104198
H2426392Certificate of AnalysisAug 09, 2024 S104198
H2426396Certificate of AnalysisAug 09, 2024 S104198
H2426395Certificate of AnalysisAug 09, 2024 S104198
H2423076Certificate of AnalysisApr 25, 2024 S104198
E2416287Certificate of AnalysisApr 25, 2024 S104198
E2416286Certificate of AnalysisApr 25, 2024 S104198
E2416285Certificate of AnalysisApr 25, 2024 S104198
E2416272Certificate of AnalysisApr 25, 2024 S104198
E2416266Certificate of AnalysisApr 25, 2024 S104198
C2416165Certificate of AnalysisMar 06, 2024 S104198
C2416083Certificate of AnalysisMar 06, 2024 S104198
C2416081Certificate of AnalysisMar 06, 2024 S104198
C2416080Certificate of AnalysisMar 06, 2024 S104198
A2425037Certificate of AnalysisNov 15, 2023 S104198
L2301271Certificate of AnalysisNov 15, 2023 S104198
L2301272Certificate of AnalysisNov 15, 2023 S104198
L2301289Certificate of AnalysisNov 15, 2023 S104198
L2301290Certificate of AnalysisNov 15, 2023 S104198
L2301291Certificate of AnalysisNov 15, 2023 S104198
J2320533Certificate of AnalysisOct 09, 2023 S104198
J2320532Certificate of AnalysisOct 09, 2023 S104198
J2320531Certificate of AnalysisOct 09, 2023 S104198
J2320530Certificate of AnalysisOct 09, 2023 S104198
H2325435Certificate of AnalysisAug 12, 2023 S104198
H2325437Certificate of AnalysisAug 12, 2023 S104198
H2325436Certificate of AnalysisAug 12, 2023 S104198
H2325434Certificate of AnalysisAug 12, 2023 S104198
A2309418Certificate of AnalysisJan 14, 2023 S104198
G2325080Certificate of AnalysisFeb 19, 2022 S104198
F2327384Certificate of AnalysisFeb 19, 2022 S104198
D2310235Certificate of AnalysisFeb 19, 2022 S104198
C2324540Certificate of AnalysisFeb 19, 2022 S104198
G2329011Certificate of AnalysisFeb 19, 2022 S104198
C2218570Certificate of AnalysisFeb 19, 2022 S104198
C2218569Certificate of AnalysisFeb 19, 2022 S104198
C2218557Certificate of AnalysisFeb 19, 2022 S104198
C2218555Certificate of AnalysisFeb 19, 2022 S104198

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Chemical and Physical Properties

SolubilitySoluble in water (330 g/l) at 15 °C, DMSO, methanol, and ethanol (very slightly).
SensitivityHygroscopic
Specific Rotation[α]42° (C=2,H2O)

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS FZ2250000

Related Documents

 SDS

 Specification Sheet

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FAQs and Articles

FAQ
Cross-linking ChIP-Seq (X-ChIP-Seq) protocol
Categories: Protocols
Tags:
Electrophoresis Cross-linking ChIP
Chromatin preparation from tissues for chromatin immunoprecipitation (ChIP)
Categories: Protocols
Tags:
Electrophoresis ChIP Lysis buffer Aprotinin

Citations of This Product

1. Jing Zhang, Kairu Liu, Xiaojuan Duan, Xuhao Wang, Wupeng Ge, Wenping Jin.  (2023)  Restoration of Choujiu Koji and evaluation of its brewing performance.  LWT-FOOD SCIENCE AND TECHNOLOGY,  183  (114933).  [PMID:]
2. Peng Weichao, Yan Shuaihu, Zhou Ke, Wu Hai-Chen, Liu Lei, Zhao Yuliang.  (2023)  High-resolution discrimination of homologous and isomeric proteinogenic amino acids in nanopore sensors with ultrashort single-walled carbon nanotubes.  Nature Communications,  14  (1): (1-8).  [PMID:37160961]
3. Sheng Liu, Bo Yang, Yingxiang Hou, Kaige Cui, Xiaozhu Yang, Xiaoxiong Li, Lianwan Chen, Shichao Liu, Zhichao Zhang, Yuanyuan Jia, Yufeng Xie, Ying Xue, Xiaomei Li, Bingxue Yan, Changxin Wu, Wen Deng, Jianxun Qi, Defen Lu, George F. Gao, Peiyi Wang, Guijun Shang.  (2023)  The mechanism of STING autoinhibition and activation.  MOLECULAR CELL,  83  (1502-1518.e10).  [PMID:37086726]
4. Qin Guo, Jie Cai, Pengyu Li, Dongling Xu, Xiaomin Ni, Hui Wen, Dan Liu, Suizhen Lin, Haiyan Hu.  (2023)  Comparison of bile salt/phosphatidylcholine mixed micelles in solubilization to sterols and stability.  Drug Design Development and Therapy,      [PMID:27895469]
5. Chuntian Shao, Jingwei Zhong, Junwen Liu, Yiyan Yang, Meilin Li, Yang Yu, Yaqin Xu, Libo Wang.  (2023)  Preparation, characterization and bioactivities of selenized polysaccharides from Lonicera caerulea L. fruits.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  225  (484).  [PMID:36403769]
6. Shuo Qi, Xiaoze Dong, Yuhan Sun, Yin Zhang, Nuo Duan, Zhouping Wang.  (2022)  Split aptamer remodeling-initiated target-self-service 3D-DNA walker for ultrasensitive detection of 17β-estradiol.  JOURNAL OF HAZARDOUS MATERIALS,  439  (129590).  [PMID:35872451]
7. Ping Li, Yiting Yang, Zijin Lin, Shijin Hong, Ling Jiang, Han Zhou, Lu Yang, Liang Zhu, Xiaodong Liu, Li Liu.  (2022)  Bile Duct Ligation Impairs Function and Expression of Mrp1 at Rat Blood–Retinal Barrier via Bilirubin-Induced P38 MAPK Pathway Activations.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  23  (14): (7666).  [PMID:35887010]
8. Wang Cong-Yu, Sun Min, Fan Zhen, Du Jian-Zhong.  (2022)  Intestine Enzyme-responsive Polysaccharide-based Hydrogel to Open Epithelial Tight Junctions for Oral Delivery of Imatinib against Colon Cancer.  CHINESE JOURNAL OF POLYMER SCIENCE,  40  (10): (1154-1164).  [PMID:]
9. Chu-tong Tian, Jing-jing Guo, Yi-fan Miao, He-lin Wang, Qing Ye, Chun-lin Guo, Ming-yang Zhang, Zhong-gui He, Jin Sun.  (2022)  Long chain triglyceride-lipid formulation promotes the oral absorption of the lipidic prodrugs through coincident intestinal behaviors.  EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS,  176  (122).  [PMID:35643367]
10. Zhang Pengpeng, Zhang Miaomiao, Dong Kaiyu, Zhang Yicong, Yang Shuang, Wang Yuanhong, Jiang Tingfu, Yu Mingming, Lv Zhihua.  (2022)  Evaluation of Chito-Oligosaccharide (COS) in Vitro and in Vivo: Permeability Characterization in Caco-2 Cells Monolayer and Pharmacokinetics Properties in Rats.  Journal of Ocean University of China,  21  (3): (782-788).  [PMID:]

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