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Sodium deoxycholate - High purity, high purity , CAS No.302-95-4

10 Citations

high-purity

CAS#: 302-95-4
Formula: C₂₄H₃₉O₄Na
Molecular Weight: 414.56
Beilstein Registry Number: 3581950
EC Number: 206-132-7
MDL number: MFCD00064139
PubChem CID: 23668196

Item Number

S274361

Grouped product items
SKU	Size	Availability	Price
S274361-50g	50g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$240.90
S274361-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$343.90
S274361-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,613.90
S274361-12×50g	12×50g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,601.90
S274361-12×100g	12×100g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,714.90
S274361-4×500g	4×500g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$5,810.90

Basic Description

Synonyms	Kybella \| sodium (3alpha,5beta,12alpha)-3,12-dihydroxycholan-24-oate \| Deoxycholic acid sodium salt \| HY-N0593A \| Na-Desoxycholat \| ISOQUINOLINIUM, 2,2'-(1,5-PENTANEDIYLBIS(OXY(3-OXO-3,1-PROPANEDIYL)))BIS(1-((3,4-DIMETHOXYPHENYL)METHYL)-1,2,3,4-TETRAHYDRO
Specifications & Purity	high-purity
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice
Grade	high-purity
Product Description	Anionic - negatively-charged (carboxylates, sulfates or sulfonates in alkali metal form). Utilized for applications ranging from solubilizing membrane proteins in non-denaturing conditions to creating denaturing conditions during gel electrophoresis. Used for complete disruption of membranes.

Associated Targets(Human)

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

Discover Target: NR3C1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)

Discover Target: PPARG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RXRA Tclin Retinoid X receptor alpha (3637 Activities)

Discover Target: RXRA

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GSTO1 Tchem Glutathione transferase omega 1 (164 Activities)

Discover Target: GSTO1

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Lymphoblastoid cell (5959 Activities)

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

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CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)

Discover Target: CBX1

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Associated Targets(non-human)

Cruzipain (33337 Activities)

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Ppard Peroxisome proliferator-activated receptor delta (358 Activities)

Discover Target: Ppard

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Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

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Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

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Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

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Names and Identifiers

IUPAC Name	sodium;(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
INCHI	InChI=1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1
InChi Key	FHHPUSMSKHSNKW-SMOYURAASA-M
Canonical SMILES	CC(CCC(=O)[O-])C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C.[Na+]
Isomeric SMILES	C[C@H](CCC(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C.[Na+]
WGK Germany	3
RTECS	FZ2250000
PubChem CID	23668196
Molecular Weight	414.56
Beilstein	3581950

Certificates

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3 results found

Lot Number	Certificate Type	Date	Item
H2304138	Certificate of Analysis	Jul 12, 2023	S274361
H2304139	Certificate of Analysis	Jul 12, 2023	S274361
H2304143	Certificate of Analysis	Jul 12, 2023	S274361

Chemical and Physical Properties

Sensitivity	Hygroscopic
Specific Rotation[α]	42° (C=2,H2O)

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	FZ2250000

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FAQs and Articles

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Cross-linking ChIP-Seq (X-ChIP-Seq) protocol

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Electrophoresis Cross-linking ChIP

Chromatin preparation from tissues for chromatin immunoprecipitation (ChIP)

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Electrophoresis ChIP Lysis buffer Aprotinin

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Jing Zhang, Kairu Liu, Xiaojuan Duan, Xuhao Wang, Wupeng Ge, Wenping Jin. (2023) Restoration of Choujiu Koji and evaluation of its brewing performance. LWT-FOOD SCIENCE AND TECHNOLOGY, 183 (114933). [PMID:]
2. Peng Weichao, Yan Shuaihu, Zhou Ke, Wu Hai-Chen, Liu Lei, Zhao Yuliang. (2023) High-resolution discrimination of homologous and isomeric proteinogenic amino acids in nanopore sensors with ultrashort single-walled carbon nanotubes. Nature Communications, 14 (1): (1-8). [PMID:37160961]
3. Sheng Liu, Bo Yang, Yingxiang Hou, Kaige Cui, Xiaozhu Yang, Xiaoxiong Li, Lianwan Chen, Shichao Liu, Zhichao Zhang, Yuanyuan Jia, Yufeng Xie, Ying Xue, Xiaomei Li, Bingxue Yan, Changxin Wu, Wen Deng, Jianxun Qi, Defen Lu, George F. Gao, Peiyi Wang, Guijun Shang. (2023) The mechanism of STING autoinhibition and activation. MOLECULAR CELL, 83 (1502-1518.e10). [PMID:37086726]
4. Qin Guo, Jie Cai, Pengyu Li, Dongling Xu, Xiaomin Ni, Hui Wen, Dan Liu, Suizhen Lin, Haiyan Hu. (2023) Comparison of bile salt/phosphatidylcholine mixed micelles in solubilization to sterols and stability. Drug Design Development and Therapy, [PMID:27895469]
5. Chuntian Shao, Jingwei Zhong, Junwen Liu, Yiyan Yang, Meilin Li, Yang Yu, Yaqin Xu, Libo Wang. (2023) Preparation, characterization and bioactivities of selenized polysaccharides from Lonicera caerulea L. fruits. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 225 (484). [PMID:36403769]
6. Shuo Qi, Xiaoze Dong, Yuhan Sun, Yin Zhang, Nuo Duan, Zhouping Wang. (2022) Split aptamer remodeling-initiated target-self-service 3D-DNA walker for ultrasensitive detection of 17β-estradiol. JOURNAL OF HAZARDOUS MATERIALS, 439 (129590). [PMID:35872451]
7. Ping Li, Yiting Yang, Zijin Lin, Shijin Hong, Ling Jiang, Han Zhou, Lu Yang, Liang Zhu, Xiaodong Liu, Li Liu. (2022) Bile Duct Ligation Impairs Function and Expression of Mrp1 at Rat Blood–Retinal Barrier via Bilirubin-Induced P38 MAPK Pathway Activations. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (14): (7666). [PMID:35887010]
8. Wang Cong-Yu, Sun Min, Fan Zhen, Du Jian-Zhong. (2022) Intestine Enzyme-responsive Polysaccharide-based Hydrogel to Open Epithelial Tight Junctions for Oral Delivery of Imatinib against Colon Cancer. CHINESE JOURNAL OF POLYMER SCIENCE, 40 (10): (1154-1164). [PMID:]
9. Chu-tong Tian, Jing-jing Guo, Yi-fan Miao, He-lin Wang, Qing Ye, Chun-lin Guo, Ming-yang Zhang, Zhong-gui He, Jin Sun. (2022) Long chain triglyceride-lipid formulation promotes the oral absorption of the lipidic prodrugs through coincident intestinal behaviors. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 176 (122). [PMID:35643367]
10. Zhang Pengpeng, Zhang Miaomiao, Dong Kaiyu, Zhang Yicong, Yang Shuang, Wang Yuanhong, Jiang Tingfu, Yu Mingming, Lv Zhihua. (2022) Evaluation of Chito-Oligosaccharide (COS) in Vitro and in Vivo: Permeability Characterization in Caco-2 Cells Monolayer and Pharmacokinetics Properties in Rats. Journal of Ocean University of China, 21 (3): (782-788). [PMID:]
11. Yu Luo, Shenyu Huang, Lie Ma. (2021) A novel detergent-based decellularization combined with carbodiimide crosslinking for improving anti-calcification of bioprosthetic heart valve. Biomedical Materials, 16 (4): (45022). [PMID:33979785]
12. Yang Min, Lu Xiaoluan, Tang Luyang, Fu Yangyang, Yang Peixin. (2020) Thermosensitive nanocomposite gel loaded zinc phthalocyanine for photodynamic therapy. JOURNAL OF POLYMER RESEARCH, 27 (9): (1-10). [PMID:]
13. Xinrui Li, Jing Su, Zul Kamal, Pengcheng Guo, Xinyi Wu, Lina Lu, Hongbing Wu, Mingfeng Qiu. (2020) Odorranalectin modified PEG–PLGA/PEG–PBLG curcumin-loaded nanoparticle for intranasal administration. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 46 (6): (899-909). [PMID:32375569]
14. Zhou Xueqing, Xie Yanli, Zhao Zhendong, Fu Wenyan. (2020) A simple strategy based on fibers coated with surfactant-functionalized multiwalled carbon nanotubes to improve the properties of solid-phase microextraction of phenols in aqueous solution. BMC Chemistry, 14 (1): (1-11). [PMID:32099973]
15. Xuejuan Zhang, Xiao Yue, Yingtong Cui, Ziyu Zhao, Ying Huang, Shihao Cai, Guanlin Wang, Wenhao Wang, Smyth Hugh, Xin Pan, Chuanbin Wu, Wen Tan. (2020) A Systematic Safety Evaluation of Nanoporous Mannitol Material as a Dry-Powder Inhalation Carrier System. JOURNAL OF PHARMACEUTICAL SCIENCES, 109 (1692). [PMID:31987851]
16. Xiaoluan Lu, Wentao Zhu, Tingyu Chen, Qianrong Peng, Changmu Yu, Min Yang. (2019) Exploration of photophysical and photochemical properties of Zinc phthalocyanine-loaded SDC/TPGS mixed micelles. CHEMICAL PHYSICS LETTERS, 735 (136737). [PMID:]
17. Xu Yingxin, Fang Tianxu, Yang Yifan, Sun Li’ang, Shen Qi. (2019) Preparation of Deoxycholate-Modified Docetaxel-Cimetidine Complex Chitosan Nanoparticles to Improve Oral Bioavailability. AAPS PHARMSCITECH, 20 (7): (1-10). [PMID:31489504]
18. Hailing Yang, Zhenjie Liu, Yonglong Song, Changjiang Hu. (2019) Hyaluronic acid-functionalized bilosomes for targeted delivery of tripterine to inflamed area with enhancive therapy on arthritis. DRUG DELIVERY, 26 (1): (820-830). [PMID:31389248]

References

1. Jing Zhang, Kairu Liu, Xiaojuan Duan, Xuhao Wang, Wupeng Ge, Wenping Jin. (2023) Restoration of Choujiu Koji and evaluation of its brewing performance. LWT-FOOD SCIENCE AND TECHNOLOGY, 183 (114933). [PMID:]
2. Peng Weichao, Yan Shuaihu, Zhou Ke, Wu Hai-Chen, Liu Lei, Zhao Yuliang. (2023) High-resolution discrimination of homologous and isomeric proteinogenic amino acids in nanopore sensors with ultrashort single-walled carbon nanotubes. Nature Communications, 14 (1): (1-8). [PMID:37160961]
3. Sheng Liu, Bo Yang, Yingxiang Hou, Kaige Cui, Xiaozhu Yang, Xiaoxiong Li, Lianwan Chen, Shichao Liu, Zhichao Zhang, Yuanyuan Jia, Yufeng Xie, Ying Xue, Xiaomei Li, Bingxue Yan, Changxin Wu, Wen Deng, Jianxun Qi, Defen Lu, George F. Gao, Peiyi Wang, Guijun Shang. (2023) The mechanism of STING autoinhibition and activation. MOLECULAR CELL, 83 (1502-1518.e10). [PMID:37086726]
4. Qin Guo, Jie Cai, Pengyu Li, Dongling Xu, Xiaomin Ni, Hui Wen, Dan Liu, Suizhen Lin, Haiyan Hu. (2023) Comparison of bile salt/phosphatidylcholine mixed micelles in solubilization to sterols and stability. Drug Design Development and Therapy, [PMID:27895469]
5. Chuntian Shao, Jingwei Zhong, Junwen Liu, Yiyan Yang, Meilin Li, Yang Yu, Yaqin Xu, Libo Wang. (2023) Preparation, characterization and bioactivities of selenized polysaccharides from Lonicera caerulea L. fruits. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 225 (484). [PMID:36403769]
6. Shuo Qi, Xiaoze Dong, Yuhan Sun, Yin Zhang, Nuo Duan, Zhouping Wang. (2022) Split aptamer remodeling-initiated target-self-service 3D-DNA walker for ultrasensitive detection of 17β-estradiol. JOURNAL OF HAZARDOUS MATERIALS, 439 (129590). [PMID:35872451]
7. Ping Li, Yiting Yang, Zijin Lin, Shijin Hong, Ling Jiang, Han Zhou, Lu Yang, Liang Zhu, Xiaodong Liu, Li Liu. (2022) Bile Duct Ligation Impairs Function and Expression of Mrp1 at Rat Blood–Retinal Barrier via Bilirubin-Induced P38 MAPK Pathway Activations. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (14): (7666). [PMID:35887010]
8. Wang Cong-Yu, Sun Min, Fan Zhen, Du Jian-Zhong. (2022) Intestine Enzyme-responsive Polysaccharide-based Hydrogel to Open Epithelial Tight Junctions for Oral Delivery of Imatinib against Colon Cancer. CHINESE JOURNAL OF POLYMER SCIENCE, 40 (10): (1154-1164). [PMID:]
9. Chu-tong Tian, Jing-jing Guo, Yi-fan Miao, He-lin Wang, Qing Ye, Chun-lin Guo, Ming-yang Zhang, Zhong-gui He, Jin Sun. (2022) Long chain triglyceride-lipid formulation promotes the oral absorption of the lipidic prodrugs through coincident intestinal behaviors. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 176 (122). [PMID:35643367]
10. Zhang Pengpeng, Zhang Miaomiao, Dong Kaiyu, Zhang Yicong, Yang Shuang, Wang Yuanhong, Jiang Tingfu, Yu Mingming, Lv Zhihua. (2022) Evaluation of Chito-Oligosaccharide (COS) in Vitro and in Vivo: Permeability Characterization in Caco-2 Cells Monolayer and Pharmacokinetics Properties in Rats. Journal of Ocean University of China, 21 (3): (782-788). [PMID:]
11. Yu Luo, Shenyu Huang, Lie Ma. (2021) A novel detergent-based decellularization combined with carbodiimide crosslinking for improving anti-calcification of bioprosthetic heart valve. Biomedical Materials, 16 (4): (45022). [PMID:33979785]
12. Yang Min, Lu Xiaoluan, Tang Luyang, Fu Yangyang, Yang Peixin. (2020) Thermosensitive nanocomposite gel loaded zinc phthalocyanine for photodynamic therapy. JOURNAL OF POLYMER RESEARCH, 27 (9): (1-10). [PMID:]
13. Xinrui Li, Jing Su, Zul Kamal, Pengcheng Guo, Xinyi Wu, Lina Lu, Hongbing Wu, Mingfeng Qiu. (2020) Odorranalectin modified PEG–PLGA/PEG–PBLG curcumin-loaded nanoparticle for intranasal administration. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 46 (6): (899-909). [PMID:32375569]
14. Zhou Xueqing, Xie Yanli, Zhao Zhendong, Fu Wenyan. (2020) A simple strategy based on fibers coated with surfactant-functionalized multiwalled carbon nanotubes to improve the properties of solid-phase microextraction of phenols in aqueous solution. BMC Chemistry, 14 (1): (1-11). [PMID:32099973]
15. Xuejuan Zhang, Xiao Yue, Yingtong Cui, Ziyu Zhao, Ying Huang, Shihao Cai, Guanlin Wang, Wenhao Wang, Smyth Hugh, Xin Pan, Chuanbin Wu, Wen Tan. (2020) A Systematic Safety Evaluation of Nanoporous Mannitol Material as a Dry-Powder Inhalation Carrier System. JOURNAL OF PHARMACEUTICAL SCIENCES, 109 (1692). [PMID:31987851]
16. Xiaoluan Lu, Wentao Zhu, Tingyu Chen, Qianrong Peng, Changmu Yu, Min Yang. (2019) Exploration of photophysical and photochemical properties of Zinc phthalocyanine-loaded SDC/TPGS mixed micelles. CHEMICAL PHYSICS LETTERS, 735 (136737). [PMID:]
17. Xu Yingxin, Fang Tianxu, Yang Yifan, Sun Li’ang, Shen Qi. (2019) Preparation of Deoxycholate-Modified Docetaxel-Cimetidine Complex Chitosan Nanoparticles to Improve Oral Bioavailability. AAPS PHARMSCITECH, 20 (7): (1-10). [PMID:31489504]
18. Hailing Yang, Zhenjie Liu, Yonglong Song, Changjiang Hu. (2019) Hyaluronic acid-functionalized bilosomes for targeted delivery of tripterine to inflamed area with enhancive therapy on arthritis. DRUG DELIVERY, 26 (1): (820-830). [PMID:31389248]

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